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| Title: | | X-RAY STRUCTURE OF A KAPOSI'S SARCOMA HERPESVIRUS LANA PEPTIDE BOUND TO THE NUCLEOSOMAL CORE | |
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| Molecular Description: | Histone H3
H4
H2A
H2B/LANA Peptide/DNA |
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| Structural Features: | B DOUBLE HELIX, INTERNAL LOOP |
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| Nucleic Acid Sequence: |
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| Protein Sequence: |
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| Primary Citation: | Barbera, A.J., Chodaparambil, J.V., Kelley-Clarke, B., Joukov, V., Walter, J.C., Luger, K., Kaye, K.M.
The nucleosomal surface as a docking station for Kaposi's sarcoma herpesvirus LANA.
Science
, 311,
pp. 856 - 861, 2006.
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| Experimental Information: | X-RAY DIFFRACTION |
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| Space Group: |
P
21
21
21
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| Cell Constants: |
| a = 106.162 | b = 109.599 | c = 182.237 | (Ångstroms) |
 = 90.00 |  = 90.00 |  = 90.00 | (degrees) |
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| Crystallization Conditions: |
| Method: | | VAPOR DIFFUSION, SITTING DROP |
| Drop: | | Manganese chloride, Potassium chloride, Potassium cacodylate |
| Reservoir: | | Potassium chloride, Potassium cacodylate |
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| Refinement: | The structure was refined using the CNS program.
The R value is
22.2
for 43460 reflections
in the resolution range 50 to
2.9 Ångstroms
with I > 0 sigma(I).
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