 |  |  |  |
| Title: |  | X-RAY STRUCTURE OF A KAPOSI'S SARCOMA HERPESVIRUS LANA PEPTIDE BOUND TO THE NUCLEOSOMAL CORE |  |
 |
| Molecular Description: | Histone H3 H4 H2A H2B/LANA Peptide/DNA |
 |
| Structural Features: | B DOUBLE HELIX, INTERNAL LOOP |
 |
| Nucleic Acid Sequence: |
|
 |
| Protein Sequence: |
|
 |
| Primary Citation: | Barbera, A.J., Chodaparambil, J.V., Kelley-Clarke, B., Joukov, V., Walter, J.C., Luger, K., Kaye, K.M.
The nucleosomal surface as a docking station for Kaposi's sarcoma herpesvirus LANA.
Science
, 311,
pp. 856 - 861, 2006.
|
 |
 |  |  |  |
| Experimental Information: | X-RAY DIFFRACTION |
 |
| Space Group: |
P
21
21
21
|
 |
| Cell Constants: |
| a = 106.162 | b = 109.599 | c = 182.237 | (Ångstroms) |
= 90.00 | = 90.00 | = 90.00 | (degrees) |
|
 |
| Crystallization Conditions: |
| Method: | | VAPOR DIFFUSION, SITTING DROP |
| Drop: | | Manganese chloride, Potassium chloride, Potassium cacodylate |
| Reservoir: | | Potassium chloride, Potassium cacodylate |
|
 |
| Refinement: | The structure was refined using the CNS program.
The R value is
22.2
for 43460 reflections
in the resolution range 50 to
2.9 Ångstroms
with I > 0 sigma(I).
|
|
|