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| Title: | | NETROPSIN BOUND TO D(CTTAATTCGAATTAAG) IN COMPLEX WITH MMLV RT CATALYTIC FRAGMENT | |
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| Molecular Description: |
Reverse transcriptase (E.C.2.7.7.49)/DNA Complex
NETROPSIN |
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| Structural Features: | B DOUBLE HELIX |
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| Nucleic Acid Sequence: |
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| Chain | B: | | (DC) (DT) (DT) (DA) (DA) (DT) (DT) (DC) |
| Chain | G: | | (DG) (DA) (DA) (DT) (DT) (DA) (DA) (DG) |
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| Protein Sequence: |
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| Primary Citation: | Goodwin, K.D., Long, E.C., Georgiadis, M.M.
A host-guest approach for determining drug-DNA interactions: an example using netropsin.
Nucleic Acids Res.
, 33,
pp. 4106 - 4116, 2005.
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| Experimental Information: | X-RAY DIFFRACTION |
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| Space Group: |
P
21
21
2
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| Cell Constants: |
| a = 54.569 | b = 145.611 | c = 46.811 | (Ångstroms) |
 = 90.00 |  = 90.00 |  = 90.00 | (degrees) |
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| Refinement: | The structure was refined using the CNS 1.0 program.
The R value is
22.0
for 31059 reflections
in the resolution range 35.5 to
1.85 Ångstroms
with Fobs > 0. sigma(Fobs).
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