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| Title: | | CRYSTAL STRUCTURE OF HETERODIMERIC L. DONOVANI TOPOISOMERASE I-VANADATE-DNA COMPLEX | |
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| Molecular Description: | PROTEIN/DNA Complex |
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| Structural Features: | B DOUBLE HELIX |
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| Nucleic Acid Sequence: |
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| Protein Sequence: |
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| Primary Citation: | Davies, D.R., Mushtaq, A., Interthal, H., Champoux, J.J., Hol, W.G.
The Structure of the Transition State of the Heterodimeric Topoisomerase I of Leishmania donovani as a Vanadate Complex with Nicked DNA.
J.Mol.Biol.
, 357,
pp. 1202 - 1210, 2006.
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| Experimental Information: | X-RAY DIFFRACTION |
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| Space Group: |
P
21
21
21
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| Cell Constants: |
| a = 72.433 | b = 106.102 | c = 126.691 | (Ångstroms) |
 = 90.00 |  = 90.00 |  = 90.00 | (degrees) |
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| Refinement: | The structure was refined using the REFMAC 5.2.0005 program.
The R value is
23.1
for 43746 reflections
in the resolution range 43.480 to
2.270 Ångstroms
with Fobs > 0.00 sigma(Fobs).
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