 | | | |
| Title: | | DNA POLYMERASE LAMBDA IN COMPLEX WITH A DNA DUPLEX CONTAINING AN UNPAIRED DTMP | |
|
| Molecular Description: | DNA polymerase lambda (E.C.2.7.7.7
E.C.4.2.99.-)/DNA Complex |
 |
| Structural Features: | B DOUBLE HELIX, bulges, nicked |
|
| Nucleic Acid Sequence: |
| | | |
| Chain | D: | | (DG) (DC) (DC) (DG) |
| Chain | P: | | (DC) (DA) (DG) (DT) (DA) (DC) (DG) |
| Chain | T: | | (DC) (DG) (DG) (DC) (DC) (DG) (DT) (DT) (DA) (DC) (DT) (DG) |
|
|
| Protein Sequence: |
|
|
| Primary Citation: | Garcia-Diaz, M., Bebenek, K., Krahn, J.M., Pedersen, L.C., Kunkel, T.A.
Structural analysis of strand misalignment during DNA synthesis by a human DNA polymerase
Cell(Cambridge,Mass.)
, 124,
pp. 331 - 342, 2006.
|
|
| | | |
| Experimental Information: | X-RAY DIFFRACTION |
|
| Space Group: |
P
21
21
21
|
|
| Cell Constants: |
| a = 56.044 | b = 62.539 | c = 139.644 | (Ångstroms) |
 = 90.00 |  = 90.00 |  = 90.00 | (degrees) |
|
|
| Refinement: | The structure was refined using the CNS 1.1 program.
The R value is
20.1
for 55284 reflections
in the resolution range 41.74 to
1.65 Ångstroms
with Fobs > 0.0 sigma(Fobs).
|
|
|
