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| Title: |  | RT29 BOUND TO D(CTTAATTCGAATTAAG) IN COMPLEX WITH MMLV RT CATALYTIC FRAGMENT |  |
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| Molecular Description: |
Reverse Transcriptase (E.C.2.7.7.49/DNA Complex |
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| Structural Features: | B DOUBLE HELIX |
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| Nucleic Acid Sequence: |
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| Chain | B: | | (DC) (DT) (DT) (DA) (DA) (DT) (DT) (DC) |
| Chain | G: | | (DG) (DA) (DA) (DT) (DT) (DA) (DA) (DG) |
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| Protein Sequence: |
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| Primary Citation: | Goodwin, K.D., Lewis, M.A., Tanious, F.A., Tidwell, R.R., Wilson, W.D., Georgiadis, M.M., Long, E.C.
A High-Throughput, High-Resolution Strategy for the Study of Site-Selective DNA Binding Agents: Analysis of a "Highly Twisted" Benzimidazole-Diamidine.
J.Am.Chem.Soc.
, 128,
pp. 7846 - 7854, 2006.
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| Experimental Information: | X-RAY DIFFRACTION |
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| Space Group: |
P
21
21
2
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| Cell Constants: |
| a = 54.552 | b = 145.65 | c = 46.838 | (Ångstroms) |
= 90. | = 90. | = 90. | (degrees) |
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| Refinement: | The structure was refined using the CNS 1.0 program.
The R value is
22.8
for 22534 reflections
in the resolution range 50. to
2.05 Ångstroms
with Fobs > 0. sigma(Fobs).
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