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| Title: |  | HUMAN DNA POLYMERASE BETA COMPLEXED WITH GAPPED DNA AND DDCTP |  |
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| Molecular Description: |
DNA POLYMERASE BETA/DNA COMPLEX + 2',3'-DIDEOXYCYTIDINE-5'-TRIPHOSPHATE |
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| Structural Features: | B DOUBLE HELIX, GAPPED |
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| Nucleic Acid Sequence: |
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| Protein Sequence: |
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| Primary Citation: | Sawaya, M.R., Prasad, R., Wilson, S.H., Kraut, J., Pelletier, H.
Crystal structures of human DNA polymerase beta complexed with gapped and nicked DNA: evidence for an induced fit mechanism.
Biochemistry
, 36,
pp. 11205 - 11215, 1997.
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| Experimental Information: | X-RAY DIFFRACTION |
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| Space Group: |
P
1
21
1
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| Cell Constants: |
| a = 50.543 | b = 79.817 | c = 54.942 | (Ångstroms) |
= 90.00 | = 107.11 | = 90.00 | (degrees) |
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| Crystallization Conditions: |
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| Refinement: | The structure was refined using the TNT V. 5-D program.
The R value is
23.2
for 21036 reflections
in the resolution range 20.000 to
2.200 Ångstroms
with Fobs > 0.000 sigma(Fobs).
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