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| Title: | | HEPATITIS C VIRUS NS3 HELICASE DOMAIN COMPLEXED WITH SINGLE STRANDED SDNA | |
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| Molecular Description: | NS3 PROTEIN/DNA COMPLEX |
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| Structural Features: | SINGLE STRAND |
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| Nucleic Acid Sequence: |
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| Chain | B: | |
(DU) (DU) (DU) (DU) (DU) (DU) (DU) (DU)
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| Protein Sequence: |
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| Primary Citation: | Kim, J.L., Morgenstern, K.A., Griffith, J.P., Dwyer, M.D., Thomson, J.A., Murcko, M.A., Lin, C., Caron, P.R.
Hepatitis C virus NS3 RNA helicase domain with a bound oligonucleotide: the crystal structure provides insights into the mode of unwinding.
Structure
, 6,
pp. 89 - 100, 1998.
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| Experimental Information: | X-RAY DIFFRACTION |
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| Space Group: |
P
21
21
2
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| Cell Constants: |
| a = 73.100 | b = 117.500 | c = 63.400 | (Ångstroms) |
 = 90.00 |  = 90.00 |  = 90.00 | (degrees) |
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| Crystallization Conditions: |
| Drop: | | PEG
6000 LI2SO4, 2-MERCAPTOETHANOL, TRIS |
| Reservoir: | | PEG
6000 |
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| Refinement: | The structure was refined using the X-PLOR 3.843 program.
The R value is
22.8
for 25780 reflections
in the resolution range 6.0 to
2.2 Ångstroms
with Fobs > 2.0 sigma(Fobs).
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