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| Title: | | DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SEVEN BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF AZT-TP (1 MILLIMOLAR) AND MNCL2 (5 MILLIMOLAR) | |
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| Molecular Description: |
DNA POLYMERASE BETA (E.C.2.7.7.7)/DNA COMPLEX + 3'-AZIDO-3'-DEOXYTHYMIDINE-5'- TRIPHOSPHATE
SOAKED IN THE PRESENCE OF AZT-TP AND MNCL2 |
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| Structural Features: | B DOUBLE HELIX |
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| Nucleic Acid Sequence: |
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| Chain | P: | | (DT) (DC) (DT) (DA) (DA) (DT) (DG) |
| Chain | T: | | (DC) (DA) (DT) (DT) (DA) (DG) (DA) (DA) |
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| Protein Sequence: |
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| Primary Citation: | Pelletier, H., Sawaya, M.R., Wolfle, W., Wilson, S.H., Kraut, J.
A structural basis for metal ion mutagenicity and nucleotide selectivity in human DNA polymerase beta.
Biochemistry
, 35,
pp. 12762 - 12777, 1996.
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| Experimental Information: | X-RAY DIFFRACTION |
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| Space Group: |
P
21
21
2
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| Cell Constants: |
| a = 179.687 | b = 57.631 | c = 48.285 | (Ångstroms) |
 = 90.00 |  = 90.00 |  = 90.00 | (degrees) |
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| Refinement: | The structure was refined using the TNT V. 5-D program.
The R value is
18.1
for 13094 reflections
in the resolution range 20.000 to
2.700 Ångstroms
with Fobs > 0.000 sigma(Fobs).
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