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| Title: | | TERNARY STRUCTURE OF HHAI METHYLTRANSFERASE WITH ADOHCY AND DNA CONTAINING 4'-THIO-2'DEOXYCYTIDINE AT THE TARGET | |
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| Molecular Description: |
CYTOSINE-SPECIFIC METHYLTRANSFERASE HHAI (E.C.2.1.1.73)/DNA COMPLEX |
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| Structural Features: | B DOUBLE HELIX, FLIPPED-OUT BASES |
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| Nucleic Acid Sequence: |
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| Chain | C: | | (DC) (DC) (DA) (DT) (DG) (5CM) (DG) (DC) (DT) (DG) (DA) (DC) |
| Chain | D: | | (DG) (DT) (DC) (DA) (DG) (4SC) (DG) (DC) (DA) (DT) (DG) (DG) |
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| Protein Sequence: |
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| Primary Citation: | Kumar, S., Horton, J.R., Jones, G.D., Walker, R.T., Roberts, R.J., Cheng, X.
DNA containing 4'-thio-2'-deoxycytidine inhibits methylation by HhaI methyltransferase.
Nucleic Acids Res.
, 25,
pp. 2773 - 2783, 1997.
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| Experimental Information: | X-RAY DIFFRACTION |
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| Space Group: |
H
3
2
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| Cell Constants: |
| a = 99.860 | b = 99.860 | c = 325.200 | (Ångstroms) |
 = 90.00 |  = 90.00 |  = 120.00 | (degrees) |
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| Refinement: | The structure was refined using the X-PLOR 3.1 program.
The R value is
18.6
for 30012 reflections
in the resolution range 5.0 to
2.05 Ångstroms
with Fobs > 0.0 sigma(Fobs).
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