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| Title: |  | TUMOR SUPPRESSOR P53 COMPLEXED WITH DNA |  |
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| Molecular Description: | P53 TUMOR SUPPRESSOR/DNA COMPLEX |
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| Structural Features: | B DOUBLE HELIX, OVERHANGING BASE |
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| Nucleic Acid Sequence: |
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| Protein Sequence: |
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| Primary Citation: | Cho, Y., Gorina, S., Jeffrey, P.D., Pavletich, N.P.
Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations.
Science
, 265,
pp. 346 - 355, 1994.
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| Experimental Information: | X-RAY DIFFRACTION |
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| Space Group: |
C
1
2
1
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| Cell Constants: |
| a = 117.500 | b = 67.900 | c = 108.800 | (Ångstroms) |
= 90.00 | = 105.50 | = 90.00 | (degrees) |
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| Refinement: | The structure was refined using the X-PLOR, TNT program.
The R value is
20.2
for 34275 reflections
in the resolution range 6.000 to
2.200 Ångstroms
with Fobs > 2.000 sigma(Fobs).
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