 |  |  |  |
| Title: |  | CRYSTAL STRUCTURE OF THE NFKB P50/P65 HETERODIMER COMPLEXED TO THE IMMUNOGLOBULIN KB DNA |  |
 |
| Molecular Description: |
NF-KAPPA B P65 AND P50 SUBUNITS/DNA COMPLEX |
 |
| Structural Features: | B DOUBLE HELIX, OVERHANGING BASES |
 |
| Nucleic Acid Sequence: |
 |  |  |  |
| Chain | C: | | (DT) (DG) (DG) (DG) (DG) (DA) (DC) (DT) (DT) (DT) (DC) (DC) |
| Chain | D: | | (DA) (DG) (DG) (DA) (DA) (DA) (DG) (DT) (DC) (DC) (DC) (DC) |
|
 |
| Protein Sequence: |
|
 |
| Primary Citation: | Chen, F.E., Huang, D.B., Chen, Y.Q., Ghosh, G.
Crystal structure of p50/p65 heterodimer of transcription factor NF-kappaB bound to DNA.
Nature
, 391,
pp. 410 - 413, 1998.
|
 |
 |  |  |  |
| Experimental Information: | X-RAY DIFFRACTION |
 |
| Space Group: |
P
43
21
2
|
 |
| Cell Constants: |
| a = 106.610 | b = 106.610 | c = 206.560 | (Ångstroms) |
= 90.00 | = 90.00 | = 90.00 | (degrees) |
|
 |
| Refinement: | The structure was refined using the X-PLOR program.
The R value is
20.8
for 19562 reflections
in the resolution range 8.0 to
2.9 Ångstroms
with Fobs > 2. sigma(Fobs).
|
|
|