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| Title: | | CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH A POLYPURINE TRACT RNA:DNA | |
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| Molecular Description: |
HIV-1 REVERSE TRANSCRIPTASE/FRAGMENT OF FAB 28//DNA/RNA Complex |
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| Structural Features: | B DOUBLE HELIX, OVERHANGING BASE |
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| Nucleic Acid Sequence: |
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| Protein Sequence: |
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| Primary Citation: | Sarafianos, S.G., Das, K., Tantillo, C., Clark Jr., A.D., Ding, J., Whitcomb, J.M., Boyer, P.L., Hughes, S.H., Arnold, E.
Crystal structure of HIV-1 reverse transcriptase in complex with a polypurine tract RNA:DNA.
EMBO J.
, 20,
pp. 1449 - 1461, 2001.
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| Experimental Information: | X-RAY DIFFRACTION |
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| Space Group: |
P
32
1
2
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| Cell Constants: |
| a = 166.160 | b = 166.160 | c = 218.810 | (Ångstroms) |
 = 90.00 |  = 90.00 |  = 120.00 | (degrees) |
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| Refinement: | The structure was refined using the X-PLOR 3.843 program.
The R value is
27.4
for 49518 reflections
in the resolution range 8.0 to
3.0 Ångstroms
with Fobs > 2.0 sigma(Fobs).
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