 | | | |
| Title: | | CRYSTAL STRUCTURE OF THE PAZ DOMAIN OF HUMAN EIF2C1 IN COMPLEX WITH A 9-MER SIRNA-LIKE DUPLEX OF DEOXYNUCLEOTIDE OVERHANG | |
|
| Molecular Description: |
Eukaryotic translation initiation factor 2C 1/5'-R(
CpGpUpGpApCpU)-D(pCpT)-3' |
 |
| Structural Features: | DOUBLE HELIX, OVERHANGING BASES |
|
| Nucleic Acid Sequence: |
|
|
| Protein Sequence: |
|
|
| Primary Citation: | Ma, J.B., Ye, K., Patel, D.J.
Structural basis for overhang-specific small interfering RNA recognition by the PAZ domain.
Nature
, 429,
pp. 318 - 322, 2004.
|
|
| | | |
| Experimental Information: | X-RAY DIFFRACTION |
|
| Space Group: |
P
64
|
|
| Cell Constants: |
| a = 100.051 | b = 100.051 | c = 34.438 | (Ångstroms) |
 = 90.00 |  = 90.00 |  = 120.00 | (degrees) |
|
|
| Refinement: | The structure was refined using the CNS 1.1 program.
The R value is
22.1
for 5873 reflections
in the resolution range 19.71 to
2.60 Ångstroms
with Fobs > 0.0 sigma(Fobs).
|
|
|
