1 72 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 GGCCGGCAUG GUCCCAGCCU CCUCGCUGGC GCCGGCUGGG CAACACCAUU GCACUCCGGU GGCGAAUGGG AC LOOP1 48 57 Crystallography ? ? Angstroms 1 G O3' 59.768 48.800 -59.534 2 G P 60.855 49.974 -59.522 O3' 61.452 53.521 -63.144 3 C P 62.747 54.430 -62.836 O3' 63.320 59.383 -63.898 4 C P 64.751 59.897 -63.357 O3' 65.228 64.845 -61.855 5 G P 66.806 64.959 -61.590 O3' 68.531 68.404 -58.101 6 G P 70.078 68.165 -57.751 O3' 72.206 69.387 -53.218 7 C P 73.740 68.959 -53.471 O3' 76.581 67.089 -49.310 8 A P 77.964 66.461 -49.825 O3' 79.888 62.047 -48.089 9 U P 81.318 62.008 -48.812 O3' 82.889 57.183 -50.507 10 G P 84.379 57.482 -50.993 O3' 83.435 54.734 -55.656 11 G P 82.743 53.273 -55.708 O3' 83.200 50.311 -59.979 12 U P 82.075 49.174 -59.781 O3' 82.634 44.299 -61.577 13 C P 81.374 43.430 -61.093 O3' 81.771 38.437 -59.248 14 C P 80.564 37.742 -58.418 O3' 80.834 34.115 -55.011 15 C P 79.282 33.831 -54.719 O3' 78.107 32.149 -49.826 16 A P 76.507 31.991 -49.795 O3' 74.114 33.311 -45.179 17 G P 72.506 33.475 -45.237 O3' 70.119 36.877 -42.121 18 C P 68.565 36.596 -42.419 O3' 65.259 40.804 -42.279 19 C P 63.743 40.403 -42.658 O3' 60.475 43.648 -44.954 20 U P 59.130 42.880 -44.567 O3' 55.802 44.125 -49.066 21 C P 54.461 44.292 -48.170 O3' 53.278 41.610 -52.005 22 C P 54.758 41.619 -52.632 O3' 57.272 41.761 -57.978 23 U P 56.837 40.823 -59.218 O3' 56.728 36.032 -58.570 24 C P 58.340 36.195 -58.675 O3' 60.408 32.731 -55.108 25 G P 60.290 31.917 -56.496 O3' 65.952 33.499 -57.116 26 C P 67.378 34.026 -56.538 O3' 68.889 33.542 -62.165 27 U P 68.482 34.033 -63.648 O3' 68.333 38.178 -61.897 28 G P 67.560 37.767 -60.541 O3' 66.462 43.399 -59.366 29 G P 67.739 44.265 -58.908 O3' 66.972 48.056 -55.270 30 C P 68.373 48.709 -54.802 O3' 69.450 50.373 -50.205 31 G P 70.406 51.270 -51.138 O3' 70.653 53.479 -46.368 32 C P 69.154 54.046 -46.178 O3' 67.772 58.206 -43.586 33 C P 66.185 58.348 -43.831 O3' 63.789 62.789 -44.529 34 G P 62.241 62.426 -44.781 O3' 59.079 65.404 -47.814 35 G P 57.666 64.744 -48.260 O3' 55.341 66.218 -52.727 36 C P 54.033 65.347 -53.051 O3' 52.210 64.429 -57.808 37 U P 50.892 63.556 -57.551 O3' 49.987 59.566 -60.991 38 G P 48.806 58.491 -60.759 O3' 48.147 54.324 -63.205 39 G P 46.762 53.672 -62.712 O3' 45.855 48.711 -63.324 40 G P 44.340 48.597 -62.817 O3' 42.796 44.472 -60.285 41 C P 41.293 45.012 -60.436 O3' 41.056 41.060 -57.478 42 A P 40.293 39.762 -56.949 O3' 42.923 35.931 -55.276 43 A P 42.406 36.065 -53.767 O3' 45.480 34.583 -49.831 44 C P 44.389 34.843 -48.679 O3' 45.902 36.850 -44.240 45 A P 44.568 37.173 -43.407 O3' 43.911 40.809 -39.974 46 C P 42.385 40.793 -39.450 O3' 39.810 45.290 -38.192 47 C P 38.267 45.014 -37.832 O3' 34.615 48.389 -39.119 48 A P 33.341 47.646 -38.495 O3' 28.928 47.421 -41.138 49 U P 28.049 46.319 -40.340 O3' 24.928 42.834 -42.950 50 U P 24.245 42.153 -41.660 O3' 21.094 37.869 -41.930 51 G P 19.966 38.483 -42.889 O3' 20.075 37.772 -48.344 52 C P 18.794 36.817 -48.491 O3' 18.518 35.693 -52.734 53 A P 17.910 35.142 -54.106 O3' 21.905 34.755 -57.527 54 C P 21.402 34.703 -59.051 O3' 23.104 31.361 -62.772 55 U P 22.825 32.672 -63.658 O3' 27.526 34.640 -61.123 56 C P 28.863 33.830 -61.499 O3' 32.514 36.264 -58.701 57 C P 31.698 36.859 -57.448 O3' 32.235 41.639 -55.791 58 G P 31.092 42.166 -54.800 O3' 33.799 47.314 -54.387 59 G P 35.367 47.631 -54.581 O3' 37.417 51.645 -51.981 60 U P 38.963 51.730 -52.396 O3' 42.569 53.454 -49.026 61 G P 43.973 53.301 -49.789 O3' 48.067 52.172 -46.742 62 G P 49.356 52.320 -47.684 O3' 53.635 49.144 -45.255 63 C P 55.192 49.247 -45.651 O3' 54.737 51.757 -49.210 64 G P 55.017 53.176 -49.903 O3' 58.942 53.063 -46.838 65 A P 59.903 53.360 -45.582 O3' 62.234 49.208 -43.693 66 A P 63.698 49.839 -43.518 O3' 67.609 46.515 -43.300 67 U P 68.740 47.593 -42.903 O3' 74.090 47.380 -41.542 68 G P 75.545 47.996 -41.251 O3' 80.483 44.991 -41.237 69 G P 81.883 45.335 -41.919 O3' 85.566 41.575 -42.383 70 G P 86.821 42.127 -43.236 O3' 89.663 38.872 -46.192 71 A P 90.913 39.600 -46.895 O3' 93.023 38.443 -51.346 72 C P 94.257 39.479 -51.403 O3' 95.470 41.418 -56.206 25 syn 1 37 W W c 2 36 + + c 3 35 + + c 4 34 + + c 5 33 + + c 6 32 + + c 7 31 + + c 11 72 + + c 12 71 - - c 13 70 + + c 14 69 + + c 15 68 + + c 16 67 - - c 17 30 + + c 18 29 + + c 19 28 + + c 21 39 + + c 21 42 S W c 22 38 + + c 29 66 S S t 40 42 S H c 41 61 W H t 43 62 W W c 44 61 + + c 45 60 - - c 46 59 + + c 47 58 + + c 55 56 S H c 40 43 ! ! ! 40 62 ! ! ! 19 65 ! ! ! 22 24 ! ! ! 51 52 ! ! ! 52 53 ! ! ! 1 37 7 21 39 2 43 62 5 11 72 6 17 30 3 SG1 8 10 SG2 20 20 SG3 23 27 SG4 40 42 SG5 48 57 SG6 63 66 1 175.578 267.295 2 175.578 245.389 3 175.578 223.483 4 175.578 201.577 5 175.578 179.671 6 175.578 157.765 7 175.578 135.859 8 175.578 122.715 9 175.578 109.571 10 175.578 96.428 11 69.999 0.000 12 62.221 20.479 13 54.444 40.958 14 46.666 61.437 15 38.888 81.916 16 31.111 102.394 17 15.555 143.352 18 7.778 163.831 19 0.000 184.310 20 188.722 333.014 21 175.578 333.014 22 175.578 311.107 23 188.722 311.107 24 201.865 311.107 25 215.009 311.107 26 228.153 311.107 27 241.296 311.107 28 49.149 202.976 29 56.927 182.498 30 64.705 162.019 31 123.003 135.859 32 123.003 157.765 33 123.003 179.671 34 123.003 201.577 35 123.003 223.483 36 123.003 245.389 37 123.003 267.295 38 123.003 311.107 39 123.003 333.014 40 109.860 333.014 41 96.716 333.014 42 83.572 333.014 43 123.003 376.826 44 123.003 398.732 45 123.003 420.638 46 123.003 442.544 47 123.003 464.450 48 108.129 480.395 49 101.970 501.313 50 105.830 522.774 51 118.891 540.236 52 138.388 550.000 53 160.193 550.000 54 179.691 540.236 55 192.752 522.774 56 196.611 501.313 57 190.452 480.395 58 175.578 464.450 59 175.578 442.544 60 175.578 420.638 61 175.578 398.732 62 175.578 376.826 63 188.722 376.826 64 201.865 376.826 65 215.009 376.826 66 228.153 376.826 67 80.260 121.061 68 88.038 100.582 69 95.815 80.103 70 103.593 59.624 71 111.371 39.145 72 119.148 18.666