NDB ID: PR0022


Title:CRYSTAL STRUCTURE OF NOVA-2 KH3 K-HOMOLOGY RNA-BINDING DOMAIN BOUND TO 20-MER RNA HAIRPIN
Molecular Description:RNA-BINDING PROTEIN NOVA-2/RNA
Structural Features:SINGLE STRAND, LOOP, FLIPPED-OUT BASES
Nucleic Acid Sequence:
ChainsC,D:G A G G A C C U A G A U C A C C C C U C
Protein Sequence:
ChainsA,B: Click here for sequence.
Primary Citation:Lewis, H.A., Musunuru, K., Jensen, K.B., Edo, C., Chen, H., Darnell, R.B., Burley, S.K.
Sequence-specific RNA binding by a Nova KH domain: implications for paraneoplastic disease and the fragile X syndrome.
Cell(Cambridge,Mass.) , 100, pp. 323 - 332, 2000.
Experimental Information:X-RAY DIFFRACTION
Space Group: 21   21   21
Cell Constants:
a = 47.850b = 51.210c = 128.600(Ångstroms)
= 90.00 = 90.00 = 90.00(degrees)
Refinement:The structure was refined using the CNS program. The R value is 20.8 for 12459 reflections in the resolution range 20.0 to 2.40 Ångstroms with I > 3.0 sigma(I).

Biological Assembly 1
Other Views
Asymmetric Unit
RNA View
RNAML File

Biological Assemblies
Enlarge Biological Assembly 1
Enlarge Biological Assembly 2



Coordinate + Structure Data

Asymmetric Unit coordinates (pdb format, Unix compressed(.gz))

Asymmetric Unit coordinates (cif format, Unix compressed(.gz))

Biological Assembly coordinates (pdb format)12

XML | Complete with coordinates (xml format, GNU compressed(.gz))
XML | Coordinates only (xml format, GNU compressed(.gz))
XML | Header only (xml format, GNU compressed(.gz))

Derivative Data

Nucleic Acid Backbone Torsions

Base Pair Parameters

Base Pair Step Parameters

Hydrogen Bonding Classification

Links

The RCSB Protein Data Bank: 1EC6

PubMed: 10676814




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