1 97 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 186 187 188 189 190 191 192 193 194 195 196 197 198 199 200 201 202 203 204 205 206 207 208 209 210 211 212 213 214 215 216 217 218 219 220 221 222 223 224 225 226 227 228 229 230 231 232 233 234 235 236 UCGGCGGUGG GGGAGCAUCU CCUGUAGGGG AGAUGUAACC CCCUUUACCU GCCGAACCCC GCCAGGCCCG GAAGGGAGCA ACGGUAGGCA GGACGUC LOOP1 24 27 LOOP2 70 73 Crystallography ? ? Angstroms 1 U O3' 85.853 71.851 -16.300 2 C P 84.998 70.554 -15.902 O3' 86.592 68.236 -11.191 3 G P 85.489 67.087 -11.112 O3' 82.950 66.644 -6.568 4 G P 81.738 65.625 -6.791 O3' 77.586 65.888 -3.926 5 C P 76.714 64.609 -4.309 O3' 71.077 64.794 -4.244 6 G P 70.699 63.336 -4.801 O3' 66.310 62.730 -7.243 7 G P 66.588 61.217 -6.789 O3' 62.863 59.846 -10.713 8 U P 62.030 59.673 -12.072 O3' 58.000 62.682 -9.130 9 G P 56.829 61.821 -8.469 O3' 51.325 63.201 -9.638 10 G P 50.384 61.943 -9.348 O3' 45.991 61.857 -11.797 11 G P 45.258 60.441 -11.687 O3' 41.384 59.037 -14.552 12 G P 40.791 57.588 -14.211 O3' 40.043 53.633 -18.059 13 G P 39.960 52.133 -17.513 O3' 40.408 48.095 -19.915 14 A P 40.254 46.945 -18.810 O3' 43.542 42.444 -19.469 15 G P 42.887 41.401 -18.453 O3' 46.376 38.203 -15.767 16 C P 45.406 37.474 -14.754 O3' 47.844 36.943 -9.913 17 A P 46.849 36.287 -8.847 O3' 46.639 36.878 -3.968 18 U P 45.438 35.868 -3.746 O3' 41.964 36.764 -0.058 19 C P 40.814 35.709 -0.264 O3' 36.034 37.248 1.215 20 U P 35.017 36.049 0.939 O3' 30.312 36.238 -1.020 21 C P 29.894 34.880 -1.709 O3' 26.098 34.999 -5.582 22 C P 25.799 33.484 -5.978 O3' 23.985 32.410 -10.735 23 U P 23.777 30.833 -10.647 O3' 25.203 27.572 -14.468 24 G P 24.888 26.087 -13.999 O3' 27.242 22.245 -16.366 25 U P 26.197 21.226 -15.741 O3' 30.135 18.222 -11.978 26 A P 31.399 19.123 -11.669 O3' 36.648 19.954 -11.007 27 G P 36.918 21.515 -11.004 O3' 41.365 23.020 -12.567 28 G P 41.247 24.573 -12.447 O3' 39.330 27.518 -17.267 29 G P 39.291 29.113 -17.317 O3' 36.110 31.573 -20.263 30 G P 36.677 33.038 -20.133 O3' 34.318 37.740 -17.914 31 A P 34.873 39.067 -17.214 O3' 32.102 42.635 -15.031 32 G P 33.081 43.845 -14.721 O3' 32.113 46.836 -10.484 33 A P 33.329 47.852 -10.333 O3' 34.844 49.676 -6.127 34 U P 36.114 50.624 -6.123 O3' 40.276 50.988 -2.893 35 G P 41.165 52.082 -3.644 O3' 45.968 50.857 -3.209 36 U P 46.800 51.919 -4.068 O3' 51.579 50.047 -6.584 37 A P 52.043 51.582 -6.575 O3' 53.444 51.036 -12.396 38 A P 53.856 50.489 -13.851 O3' 57.044 47.095 -15.564 39 C P 57.514 46.660 -17.036 O3' 55.671 46.325 -21.651 40 C P 55.598 47.310 -22.903 O3' 53.045 49.892 -25.633 41 C P 53.493 51.288 -26.262 O3' 49.985 55.249 -27.576 42 C P 50.945 56.219 -28.422 O3' 49.451 61.229 -26.801 43 C P 50.364 62.540 -26.851 O3' 50.575 65.657 -24.503 44 U P 52.027 65.477 -25.155 O3' 52.822 70.067 -24.398 45 U P 53.660 70.019 -25.770 O3' 57.783 72.379 -22.871 46 U P 58.826 71.242 -22.266 O3' 59.938 67.484 -19.258 47 A P 60.098 65.901 -19.473 O3' 61.560 61.979 -17.897 48 C P 61.616 60.385 -17.851 O3' 64.488 57.966 -22.134 49 C P 64.554 56.444 -21.662 O3' 68.729 54.203 -24.702 50 U P 69.472 52.787 -24.625 O3' 73.970 50.234 -22.879 51 G P 72.851 49.333 -23.585 O3' 75.926 45.517 -20.903 52 C P 75.054 44.299 -20.379 O3' 77.400 42.562 -16.065 53 C P 76.602 41.481 -15.204 O3' 74.992 40.823 -9.744 54 G P 73.772 39.964 -9.169 O3' 70.056 40.013 -6.946 55 A P 69.532 38.645 -7.602 O3' 65.714 37.469 -4.611 56 A P 65.433 36.020 -5.240 O3' 68.896 37.192 -1.388 57 C P 67.428 37.744 -1.048 O3' 63.905 33.989 -2.258 58 C P 62.619 33.320 -2.951 O3' 59.640 37.776 -3.050 59 C P 60.305 38.826 -2.037 O3' 56.098 40.119 -4.791 60 C P 55.500 38.874 -5.579 O3' 52.770 39.235 -10.042 61 G P 52.633 37.751 -10.631 O3' 51.873 37.079 -15.785 62 C P 51.303 35.591 -15.908 O3' 53.656 32.548 -19.528 63 C P 52.990 31.121 -19.306 O3' 56.145 26.793 -19.956 64 A P 55.667 25.297 -19.765 O3' 58.300 21.688 -22.381 65 G P 57.295 20.493 -21.938 O3' 58.876 16.101 -19.378 66 G P 57.441 15.475 -19.073 O3' 56.794 13.493 -14.267 67 C P 55.292 12.959 -14.177 O3' 52.445 13.593 -10.137 68 C P 51.150 12.904 -10.644 O3' 46.145 14.549 -9.639 69 C P 45.334 13.244 -10.001 O3' 40.719 13.428 -12.150 70 G P 40.756 11.906 -12.637 O3' 38.955 10.832 -17.154 71 G P 39.327 9.284 -17.096 O3' 43.222 8.586 -20.777 72 A P 44.083 9.935 -20.742 O3' 44.737 12.410 -25.786 73 A P 45.545 13.764 -25.667 O3' 43.817 17.855 -28.131 74 G P 44.723 18.989 -27.517 O3' 42.841 23.186 -24.427 75 G P 43.720 24.452 -23.922 O3' 43.698 26.057 -18.639 76 G P 44.980 26.850 -18.174 O3' 45.505 27.186 -12.961 77 A P 46.531 28.390 -12.994 O3' 49.777 28.203 -8.491 78 G P 50.819 29.312 -8.991 O3' 55.800 27.748 -8.343 79 C P 56.995 28.780 -8.608 O3' 62.048 27.608 -8.246 80 A P 62.590 28.859 -9.070 O3' 67.073 28.379 -11.650 81 A P 67.398 29.898 -12.068 O3' 68.791 30.976 -17.100 82 C P 68.929 32.569 -17.071 O3' 66.727 35.701 -20.215 83 G P 67.211 37.086 -19.553 O3' 64.343 40.984 -20.418 84 G P 64.965 42.383 -19.934 O3' 61.927 45.879 -17.000 85 U P 62.481 47.245 -16.359 O3' 60.995 49.582 -11.857 86 A P 62.094 50.659 -11.406 O3' 62.152 52.018 -6.672 87 G P 63.310 53.109 -6.814 O3' 67.756 52.331 -3.757 88 G P 68.770 53.534 -4.028 O3' 74.054 52.728 -4.566 89 C P 74.820 53.979 -5.193 O3' 79.439 53.735 -7.870 90 A P 79.621 55.257 -8.314 O3' 82.000 56.321 -13.388 91 G P 82.115 57.825 -12.856 O3' 80.890 60.035 -17.131 92 G P 80.107 61.414 -17.281 O3' 78.552 63.343 -21.768 93 A P 78.907 64.774 -21.153 O3' 75.141 68.063 -21.575 94 C P 74.201 69.347 -21.392 O3' 69.502 71.117 -20.687 95 G P 68.365 71.833 -19.816 O3' 66.731 73.642 -15.830 96 U P 67.371 75.031 -15.415 O3' 68.094 76.014 -9.873 97 C P 68.908 77.333 -9.555 O3' 72.202 77.549 -4.703 47 syn 3 97 + + c 4 96 W W c 5 95 + + c 6 94 + + c 9 43 + + c 10 42 + + c 11 41 + + c 12 40 + + c 13 39 + + c 15 36 W W c 16 35 + + c 17 34 - - c 18 33 - - c 19 32 + + c 20 31 - - c 21 30 + + c 22 29 + + c 23 28 W W c 24 27 W H t 26 73 W W t 27 74 S S t 48 92 + + c 49 91 + + c 50 90 - - c 51 89 + + c 52 88 + + c 53 87 + + c 54 86 S H t 55 85 H W t 57 58 S . c 59 84 + + c 60 83 + + c 61 82 + + c 63 79 W H t 63 80 S H t 64 79 H W t 65 78 H S t 66 77 W W c 67 76 + + c 68 75 + + c 69 74 + + c 70 73 S H t 38 84 ! ! ! 62 81 ! ! ! 7 47 ! ! ! 16 61 ! ! ! 26 69 ! ! ! 37 85 ! ! ! 38 59 ! ! ! 58 60 ! ! ! 25 26 ! ! ! 39 84 ! ! ! 39 85 ! ! ! 55 57 ! ! ! 78 79 ! ! ! 92 93 ! ! ! 3 97 4 48 92 8 9 43 5 15 36 9 65 78 5 60 83 4 SG1 1 2 SG2 7 8 SG3 14 14 SG4 24 27 SG5 37 38 SG6 44 47 SG7 56 59 SG8 64 64 SG9 70 73 SG10 79 79 SG11 84 84 SG12 93 93 1 101.830 0.000 2 98.393 11.049 3 94.955 22.099 4 89.227 40.515 5 83.498 58.930 6 77.769 77.346 7 66.719 73.909 8 55.670 70.472 9 183.277 192.483 10 183.277 211.769 11 183.277 231.055 12 183.277 250.341 13 183.277 269.628 14 183.277 288.914 15 183.277 346.773 16 183.277 366.059 17 183.277 385.345 18 183.277 404.631 19 183.277 423.918 20 183.277 443.204 21 183.277 462.490 22 183.277 481.777 23 183.277 501.063 24 180.669 523.030 25 195.360 539.568 26 217.481 539.568 27 232.172 523.030 28 229.564 501.063 29 229.564 481.777 30 229.564 462.490 31 229.564 443.204 32 229.564 423.918 33 229.564 404.631 34 229.564 385.345 35 229.564 366.059 36 229.564 346.773 37 229.564 327.486 38 229.564 308.200 39 229.564 269.628 40 229.564 250.341 41 229.564 231.055 42 229.564 211.769 43 229.564 192.483 44 22.113 100.429 45 33.163 103.866 46 44.212 107.303 47 55.262 110.741 48 66.311 114.178 49 60.583 132.594 50 54.854 151.009 51 49.125 169.425 52 43.396 187.841 53 37.667 206.257 54 31.938 224.672 55 26.210 243.088 56 22.772 254.138 57 19.335 265.187 58 15.898 276.237 59 12.461 287.286 60 54.779 319.051 61 54.249 338.330 62 53.719 357.609 63 53.189 376.888 64 52.660 396.167 65 51.600 434.725 66 51.070 454.004 67 50.540 473.283 68 50.010 492.562 69 49.480 511.841 70 51.484 533.871 71 36.344 550.000 72 14.231 549.392 73 0.000 532.456 74 3.211 510.569 75 3.741 491.290 76 4.270 472.011 77 4.800 452.732 78 5.330 433.453 79 5.860 414.174 80 6.920 375.617 81 7.450 356.338 82 7.980 337.059 83 8.510 317.780 84 66.970 267.887 85 70.408 256.837 86 76.136 238.422 87 81.865 220.006 88 87.594 201.590 89 93.323 183.174 90 99.052 164.758 91 104.780 146.343 92 110.509 127.927 93 133.016 94.533 94 121.967 91.095 95 127.696 72.680 96 133.424 54.264 97 139.153 35.848