1 12 1 2 3 4 5 6 7 8 9 10 11 12 GGCCACCUGA CA Crystallography ? ? Angstroms 1 G O3' 109.172 52.803 4.928 2 G P 107.575 52.752 4.779 O3' 104.388 57.363 4.820 3 C P 102.848 57.217 4.383 O3' 99.789 60.422 1.926 4 C P 98.595 59.534 1.327 O3' 95.870 59.969 -2.786 5 A P 95.216 58.550 -3.164 O3' 93.872 57.900 -8.194 6 C P 93.017 56.571 -7.910 O3' 93.608 52.905 -11.865 7 C P 93.056 51.408 -11.652 O3' 95.020 47.148 -13.103 8 U P 93.723 46.347 -12.601 O3' 94.895 41.449 -11.272 9 G P 93.509 40.964 -10.630 O3' 93.634 37.816 -6.524 10 A P 92.201 37.669 -5.814 O3' 91.993 36.154 -0.871 11 C P 90.420 35.850 -0.751 O3' 87.571 37.412 3.307 12 A P 86.155 36.821 2.823 O3' 81.903 40.820 2.891 SG1 1 1 SG2 8 8 SG3 12 12 1 25.211 352.368 2 32.902 347.988 3 45.721 340.688 4 58.539 333.389 5 71.358 326.089 6 84.177 318.789 7 96.995 311.489 8 101.375 319.181 9 122.633 296.890 10 135.452 289.590 11 148.270 282.290 12 155.961 277.910 1 9 13 14 15 16 17 18 19 20 21 gUCCUCUC C 1 5CG Crystallography ? ? Angstroms 1 g O3' 75.106 41.578 4.552 2 U P 74.325 41.644 3.154 O3' 71.534 45.197 1.391 3 C P 70.714 44.446 0.237 O3' 69.947 45.540 -4.593 4 C P 69.252 44.205 -5.156 O3' 69.433 42.580 -9.859 5 U P 68.533 41.256 -9.760 O3' 69.257 37.496 -13.012 6 C P 68.297 36.269 -12.628 O3' 69.411 31.590 -13.403 7 U P 68.059 30.896 -12.902 O3' 68.156 26.144 -11.124 8 C P 66.657 25.844 -10.636 O3' 65.673 22.719 -6.699 9 C P 64.083 22.645 -6.474 O3' 61.850 22.253 -2.176 SG1 1 3 1 237.256 232.812 2 244.033 227.119 3 250.809 221.426 4 257.586 215.732 5 268.881 206.243 6 280.175 196.754 7 291.470 187.266 8 302.764 177.777 9 314.059 168.288 1 92 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 GGAGAGAGA AGUCAACCAG AGAAACACAC CAACCCAUUG CACUCCGGGU UGGUGGUAUA UUACCUGGUA CGGGGGAAAC UUCGUGGUGG CCG LOOP1 36 45 LOOP2 76 77 Crystallography ? ? Angstroms 1 G O3' 64.872 35.928 5.006 2 G P 66.448 35.804 4.740 O3' 69.165 31.564 5.664 3 A P 70.653 31.609 5.076 O3' 73.603 28.218 3.501 4 G P 74.965 28.869 2.958 O3' 78.112 27.761 -1.797 5 A P 79.345 28.748 -2.064 O3' 80.937 30.073 -6.591 6 G P 82.051 31.230 -6.481 O3' 82.947 34.501 -9.906 7 A P 84.054 35.367 -9.132 O3' 83.965 40.196 -11.210 8 G P 84.859 41.369 -10.584 O3' 83.365 46.176 -7.785 9 A P 84.693 46.839 -7.198 O3' 83.256 51.450 -5.309 10 A P 84.745 51.892 -4.915 O3' 85.315 54.110 -0.288 11 G P 86.912 54.269 -0.397 O3' 89.637 52.895 3.948 12 U P 91.206 53.018 3.629 O3' 94.709 50.114 6.225 13 C P 96.139 50.323 5.516 O3' 99.252 46.172 4.997 14 A P 100.599 46.616 4.234 O3' 103.393 41.935 2.531 15 A P 104.874 41.928 1.916 O3' 102.046 37.769 -1.314 16 C P 100.973 37.183 -0.272 O3' 99.918 32.350 0.428 17 C P 98.622 32.517 1.348 O3' 97.049 28.854 4.624 18 A P 96.048 29.446 5.731 O3' 95.539 27.818 10.457 19 G P 94.395 28.741 11.114 O3' 94.248 29.561 16.125 20 A P 93.053 30.569 16.489 O3' 92.881 35.432 19.565 21 G P 91.413 36.018 19.291 O3' 91.129 40.878 18.474 22 A P 89.522 40.950 18.510 O3' 88.582 46.185 17.323 23 A P 87.298 46.891 16.672 O3' 88.063 51.487 14.096 24 A P 86.685 51.941 13.415 O3' 86.714 54.051 8.684 25 C P 85.172 54.483 8.709 O3' 82.285 53.718 4.330 26 A P 80.717 54.028 4.532 O3' 76.945 51.397 2.479 27 C P 75.627 52.079 3.091 O3' 71.484 49.472 4.596 28 A P 70.359 50.326 5.359 O3' 67.232 49.092 9.155 29 C P 66.392 50.415 9.490 O3' 64.700 51.283 14.254 30 C P 64.182 52.776 14.553 O3' 64.242 55.375 18.737 31 A P 63.675 56.842 18.483 O3' 64.671 60.914 21.074 32 A P 63.834 62.113 20.418 O3' 65.384 66.694 20.561 33 C P 64.497 67.635 19.623 O3' 66.008 71.836 16.080 34 C P 64.689 72.224 15.273 O3' 65.780 73.935 10.507 35 C P 64.335 74.212 9.873 O3' 63.418 73.843 4.976 36 A P 61.853 74.159 4.809 O3' 58.983 71.783 1.556 37 U P 57.448 72.189 1.746 O3' 53.138 69.342 1.634 38 U P 52.010 70.463 1.834 O3' 47.040 69.362 2.397 39 G P 46.831 68.686 0.964 O3' 47.001 63.162 0.859 40 C P 45.429 62.918 0.574 O3' 44.040 57.927 1.545 41 A P 44.458 57.083 0.252 O3' 47.407 53.691 2.878 42 C P 47.251 52.271 2.187 O3' 46.750 48.055 5.296 43 U P 46.840 47.006 4.097 O3' 51.209 47.673 6.308 44 C P 51.345 49.266 6.417 O3' 55.258 51.776 8.826 45 C P 55.001 53.269 8.272 O3' 58.931 56.077 5.980 46 G P 58.426 57.254 5.015 O3' 63.721 58.664 2.963 47 G P 65.143 58.504 3.675 O3' 68.901 61.551 2.359 48 G P 70.092 61.135 3.327 O3' 73.508 64.538 4.984 49 U P 74.597 63.757 5.865 O3' 77.137 65.667 9.438 50 U P 78.070 64.723 10.319 O3' 79.077 63.894 15.758 51 G P 79.865 62.515 15.623 O3' 79.079 59.647 19.883 52 G P 79.801 58.267 19.517 O3' 77.345 54.241 21.996 53 U P 78.243 52.957 21.637 O3' 75.861 48.302 21.623 54 G P 76.916 47.216 21.106 O3' 74.938 43.121 18.339 55 G P 76.130 42.070 18.113 O3' 75.031 38.327 13.611 56 U P 74.703 36.814 14.017 O3' 79.937 34.615 11.886 57 A P 80.676 35.401 10.710 O3' 80.126 39.284 13.626 58 U P 80.978 39.393 14.978 O3' 84.840 34.987 14.331 59 A P 86.226 35.589 13.769 O3' 86.827 35.058 8.733 60 U P 88.382 34.877 8.403 O3' 91.694 38.452 5.337 61 U P 93.087 37.943 4.741 O3' 97.085 41.987 6.673 62 A P 97.892 41.521 7.974 O3' 100.838 45.850 9.247 63 C P 102.094 44.958 9.719 O3' 103.512 44.463 14.565 64 C P 104.566 43.256 14.433 O3' 105.111 39.877 18.269 65 U P 106.346 39.034 17.687 O3' 106.999 34.060 18.678 66 G P 108.149 33.414 17.769 O3' 108.348 28.570 14.593 67 G P 109.914 28.857 14.373 O3' 110.088 26.455 9.202 68 U P 111.070 26.720 7.965 O3' 109.884 25.891 3.287 69 A P 111.414 26.094 2.848 O3' 112.509 27.629 -2.004 70 C P 114.086 27.908 -1.900 O3' 117.051 32.620 -3.554 71 G P 118.500 32.588 -2.863 O3' 121.137 36.741 -1.524 72 G P 122.363 36.368 -0.554 O3' 124.812 39.055 2.299 73 G P 125.903 37.866 2.372 O3' 128.207 37.943 6.579 74 G P 129.260 36.730 6.601 O3' 131.445 34.645 10.588 75 G P 132.191 33.377 9.942 O3' 132.653 28.799 12.152 76 A P 133.770 28.378 11.072 O3' 130.725 25.248 7.356 77 A P 129.145 25.483 7.196 O3' 125.734 21.791 8.940 78 A P 124.229 22.327 9.104 O3' 120.540 21.535 12.490 79 C P 119.607 22.536 11.633 O3' 118.722 26.475 15.350 80 U P 117.479 27.470 15.123 O3' 118.399 32.326 16.826 81 U P 117.142 33.255 16.471 O3' 117.694 38.718 14.612 82 C P 116.307 39.401 14.189 O3' 115.845 42.984 9.700 83 G P 114.304 43.338 9.416 O3' 112.814 44.583 4.623 84 U P 111.249 44.581 4.251 O3' 108.832 42.720 -0.794 85 G P 108.413 44.267 -0.950 O3' 107.147 44.707 -6.109 86 G P 107.788 46.117 -6.530 O3' 107.030 47.239 -11.694 87 U P 107.875 48.602 -11.813 O3' 107.133 52.862 -14.383 88 G P 108.270 53.901 -13.920 O3' 107.383 59.087 -14.132 89 G P 108.584 59.858 -13.395 O3' 107.083 64.308 -10.754 90 C P 108.234 65.050 -9.908 O3' 106.988 67.831 -5.572 91 C P 108.227 68.503 -4.796 O3' 109.917 68.458 0.840 92 G P 111.299 69.267 0.634 O3' 112.971 63.961 -0.262 57 syn 73 syn 76 syn 92 syn 15 68 - - c 16 67 + + c 17 66 + + c 18 65 - - c 19 64 + + c 20 63 W W c 21 62 S H t 22 60 H W t 23 59 H W t 26 55 W W c 27 54 + + c 28 53 - - c 29 52 + + c 30 51 + + c 31 50 - - c 32 49 - - c 33 48 + + c 34 47 + + c 35 46 + + c 69 84 - - c 70 83 + + c 71 82 + + c 72 81 W W c 74 79 W W c 75 78 W H t 24 57 ! ! ! 27 55 ! ! ! 73 80 ! ! ! 10 25 ! ! ! 39 40 ! ! ! 40 41 ! ! ! 43 44 ! ! ! 56 57 ! ! ! 26 55 10 22 60 2 15 68 7 69 84 7 SG1 7 10 SG2 14 14 SG3 24 25 SG4 36 45 SG5 56 58 SG6 61 61 SG7 76 77 SG8 91 92 1 291.285 141.181 2 279.991 150.670 3 268.696 160.159 4 257.402 169.648 5 246.107 179.137 6 234.813 188.626 7 161.516 234.006 8 153.824 238.386 9 146.133 242.766 10 138.442 247.145 11 130.751 251.525 12 117.932 258.825 13 105.113 266.125 14 100.733 258.434 15 170.729 411.644 16 170.729 396.893 17 170.729 382.141 18 170.729 367.390 19 170.729 352.638 20 170.729 337.887 21 170.729 323.135 22 170.729 293.633 23 170.729 278.881 24 170.729 249.378 25 170.729 219.875 26 170.729 190.372 27 170.729 175.621 28 170.729 160.869 29 170.729 146.118 30 170.729 131.366 31 170.729 116.615 32 170.729 101.863 33 170.729 87.112 34 170.729 72.360 35 170.729 57.609 36 180.745 46.871 37 184.892 32.786 38 182.293 18.334 39 173.498 6.575 40 160.369 0.000 41 145.685 0.000 42 132.555 6.575 43 123.760 18.334 44 121.161 32.786 45 125.309 46.871 46 135.325 57.609 47 135.325 72.360 48 135.325 87.112 49 135.325 101.863 50 135.325 116.615 51 135.325 131.366 52 135.325 146.118 53 135.325 160.869 54 135.325 175.621 55 135.325 190.372 56 135.325 205.124 57 135.325 234.627 58 135.325 264.130 59 135.325 278.881 60 135.325 293.633 61 135.325 308.384 62 135.325 323.135 63 135.325 337.887 64 135.325 352.638 65 135.325 367.390 66 135.325 382.141 67 135.325 396.893 68 135.325 411.644 69 135.325 441.147 70 135.325 455.899 71 135.325 470.650 72 135.325 485.402 73 135.325 500.153 74 135.325 514.905 75 135.325 529.656 76 142.277 550.000 77 163.776 550.000 78 170.729 529.656 79 170.729 514.905 80 170.729 500.153 81 170.729 485.402 82 170.729 470.650 83 170.729 455.899 84 170.729 441.147 85 79.476 280.724 86 66.657 288.024 87 53.839 295.324 88 41.020 302.624 89 28.201 309.924 90 15.382 317.223 91 7.691 321.603 92 0.000 325.983 2 90 + + c 3 89 + + c 4 88 + + c 4 89 W W c 5 87 - - c 6 86 + + c 7 85 + + c 9 13 + + c 10 12 - - c 11 11 + + c 2 90 6 9 13 3 1 25 + + c 4 6 + + c 4 7 W W c 5 5 - - c 6 4 + + c 7 3 - - c 8 2 + + c 9 1 + + c 2 8 ! ! ! 4 6 6