1 34 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 GGCACCUGAC CCCAUGCCGA ACUCAGAAGU GCCC LOOP1 16 19 Crystallography ? ? Angstroms 1 G O3' 46.719 -10.085 23.571 2 G P 45.296 -9.431 23.230 O3' 41.287 -9.951 26.537 3 C P 40.171 -9.321 25.560 O3' 36.062 -6.574 27.606 4 A P 35.328 -5.808 26.391 O3' 33.228 -1.159 26.590 5 C P 32.799 -0.850 25.058 O3' 32.849 4.084 23.369 6 C P 32.379 4.029 21.833 O3' 34.186 6.316 17.882 7 U P 33.243 5.830 16.670 O3' 34.854 4.772 12.042 8 G P 33.981 3.955 10.962 O3' 35.972 -0.013 7.198 9 A P 34.937 -0.755 6.221 O3' 35.136 -5.684 4.234 10 C P 36.433 -5.469 3.282 O3' 38.617 -10.530 2.442 11 C P 37.718 -11.719 3.050 O3' 38.418 -15.580 5.937 12 C P 36.866 -15.946 5.762 O3' 35.060 -19.524 9.274 13 C P 33.621 -19.633 8.556 O3' 29.570 -18.454 11.740 14 A P 28.245 -18.521 10.836 O3' 24.267 -15.321 12.234 15 U P 22.978 -15.538 11.311 O3' 19.081 -12.284 11.672 16 G P 18.374 -11.133 12.580 O3' 16.457 -13.452 8.176 17 C P 16.451 -13.123 6.599 O3' 19.898 -8.701 5.611 18 C P 21.422 -8.918 6.039 O3' 24.139 -4.725 7.499 19 G P 25.499 -5.582 7.545 O3' 27.290 -3.459 12.303 20 A P 27.235 -1.886 12.525 O3' 25.638 -2.029 17.516 21 A P 26.774 -2.986 18.131 O3' 26.032 -7.390 20.677 22 C P 27.576 -7.717 20.983 O3' 29.738 -12.240 20.387 23 U P 31.335 -12.052 20.412 O3' 34.940 -14.032 17.379 24 C P 36.300 -13.425 17.983 O3' 40.235 -11.903 14.850 25 A P 41.387 -11.029 15.576 O3' 44.035 -7.543 13.081 26 G P 45.117 -7.284 14.228 O3' 47.254 -2.547 14.589 27 A P 48.435 -3.589 14.915 O3' 49.866 0.942 18.073 28 A P 48.786 1.991 17.482 O3' 50.530 6.899 16.891 29 G P 49.138 7.507 16.351 O3' 46.534 7.911 20.513 30 U P 46.970 7.637 22.034 O3' 44.632 8.745 26.021 31 G P 45.597 8.044 27.094 O3' 44.155 6.496 31.752 32 C P 45.545 5.921 32.316 O3' 45.287 1.971 35.784 33 C P 46.803 1.528 36.091 O3' 48.063 -3.253 37.382 34 C P 49.668 -3.293 37.386 O3' 52.149 -7.473 36.840 19 syn 27 syn 1 33 + + c 2 32 + + c 3 31 + + c 4 30 - - c 5 29 + + c 6 26 + + c 7 25 - - c 8 24 + + c 9 23 - - c 11 24 W S c 12 23 W S c 13 19 + + c 14 21 S W c 19 22 S W t 15 20 ! ! ! 10 25 ! ! ! 15 18 ! ! ! 28 29 ! ! ! 1 33 5 6 26 4 14 21 2 SG1 10 13 SG2 16 19 SG3 22 22 SG4 27 28 SG5 34 34 1 40.837 8.271 2 40.837 22.057 3 40.837 35.843 4 40.837 49.628 5 40.837 63.414 6 40.837 104.771 7 40.837 118.556 8 40.837 132.342 9 40.837 146.128 10 40.837 159.913 11 40.837 187.485 12 40.837 201.270 13 40.837 215.056 14 40.837 228.841 15 40.837 242.627 16 38.973 258.329 17 49.474 270.150 18 65.286 270.150 19 75.787 258.329 20 73.922 242.627 21 73.922 228.841 22 73.922 173.699 23 73.922 146.128 24 73.922 132.342 25 73.922 118.556 26 73.922 104.771 27 73.922 90.985 28 73.922 77.200 29 73.922 63.414 30 73.922 49.628 31 73.922 35.843 32 73.922 22.057 33 73.922 8.271 34 73.922 0.000 1 34 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 GGCACC UGACCCCAUG CCGAACUCAG AAGUGCCC LOOP2 16 19 Crystallography ? ? Angstroms 1 G O3' -1.285 -5.106 14.568 2 G P 0.240 -4.689 14.891 O3' 4.407 -4.416 11.922 3 C P 5.498 -4.299 13.097 O3' 9.914 -1.458 12.310 4 A P 10.615 -1.554 13.764 O3' 13.262 2.555 15.465 5 C P 13.708 2.206 16.971 O3' 14.053 5.764 20.696 6 C P 14.504 4.919 21.984 O3' 12.589 5.705 26.675 7 U P 13.575 4.686 27.425 O3' 11.654 1.850 31.417 8 G P 12.708 0.678 31.741 O3' 10.283 -3.865 33.605 9 A P 11.301 -5.056 33.970 O3' 10.229 -10.452 33.973 10 C P 8.726 -10.836 34.467 O3' 7.888 -14.602 32.548 11 C P 6.611 -15.539 32.832 O3' 5.593 -18.532 28.410 12 C P 7.036 -19.191 28.190 O3' 8.411 -20.963 23.524 13 C P 9.846 -21.532 23.961 O3' 14.055 -19.453 21.565 14 A P 15.327 -20.024 22.377 O3' 19.690 -16.967 22.208 15 U P 20.956 -17.617 22.969 O3' 25.208 -13.935 24.252 16 G P 26.244 -14.188 23.053 O3' 27.754 -18.376 26.739 17 C P 27.709 -18.561 28.335 O3' 24.715 -14.573 30.917 18 C P 23.194 -14.522 30.445 O3' 21.037 -9.578 30.883 19 G P 19.562 -10.172 30.713 O3' 18.063 -6.046 27.381 20 A P 18.468 -4.587 27.879 O3' 20.145 -2.849 23.312 21 A P 18.958 -3.342 22.354 O3' 19.029 -6.331 18.025 22 C P 17.464 -6.326 17.669 O3' 14.823 -10.612 16.545 23 U P 13.304 -10.070 16.570 O3' 9.212 -12.539 18.512 24 C P 8.024 -11.498 18.155 O3' 4.292 -11.155 21.794 25 A P 3.272 -9.916 21.633 O3' 1.001 -7.218 25.114 26 G P 0.084 -6.183 24.284 O3' -1.018 -1.523 26.606 27 A P -2.339 -1.689 25.693 O3' -3.308 3.325 24.331 28 A P -2.251 4.193 25.178 O3' -3.707 8.073 27.933 29 G P -2.186 8.320 28.388 O3' 0.736 10.180 24.520 30 U P 0.272 10.720 23.079 O3' 2.974 13.028 19.521 31 G P 2.150 12.994 18.144 O3' 4.045 12.796 13.467 32 C P 2.627 12.799 12.695 O3' 2.720 10.603 7.720 33 C P 1.295 10.321 7.018 O3' -0.674 5.417 4.539 34 C P -2.179 5.012 4.139 O3' -2.414 6.747 8.055 19 syn 1 33 + + c 2 32 + + c 3 31 + + c 4 30 - - c 5 29 + + c 6 26 + + c 7 25 - - c 8 24 + + c 9 23 - - c 12 23 W S c 13 19 + + c 14 21 S W c 15 20 S H t 19 22 S W t 10 13 ! ! ! 11 24 ! ! ! 15 18 ! ! ! 28 29 ! ! ! 1 33 5 6 26 4 14 21 2 SG1 10 13 SG2 16 19 SG3 22 22 SG4 27 28 SG5 34 34 1 162.828 525.370 2 155.482 513.705 3 148.136 502.040 4 140.790 490.374 5 133.443 478.709 6 111.404 443.714 7 104.058 432.049 8 96.712 420.384 9 89.365 408.718 10 82.019 397.053 11 67.326 373.723 12 59.980 362.058 13 52.634 350.393 14 45.288 338.728 15 37.941 327.062 16 31.151 312.783 17 15.966 308.375 18 2.586 316.801 19 0.000 332.401 20 9.945 344.694 21 17.291 356.359 22 46.676 403.019 23 61.369 426.350 24 68.715 438.015 25 76.062 449.680 26 83.408 461.345 27 90.754 473.010 28 98.101 484.675 29 105.447 496.340 30 112.793 508.006 31 120.139 519.671 32 127.486 531.336 33 134.832 543.001 34 139.240 550.000 22 18 ! ! !