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| Title: | | CRYSTAL STRUCTURE OF NF-KB(P50)2 COMPLEXED TO A HIGH-AFFINITY RNA APTAMER | |
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| Molecular Description: |
Nuclear factor NF-kappa-B p105 subunit/RNA Complex |
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| Structural Features: | SINGLE STRAND, LOOP |
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| Nucleic Acid Sequence: |
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| Chains | C,D: | | C A U A C U U G A A A C U G U A A G G U U G G C G U A U G |
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| Protein Sequence: |
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| Primary Citation: | Huang, D.B., Vu, D., Cassiday, L.A., Zimmerman, J.M., Maher III, L.J., Ghosh, G.
Crystal structure of NF-kappaB (p50)2 complexed to a high-affinity RNA aptamer.
Proc.Natl.Acad.Sci.USA
, 100,
pp. 9268 - 9273, 2003.
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| Experimental Information: | X-RAY DIFFRACTION |
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| Space Group: |
C
1
2
1
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| Cell Constants: |
| a = 76.753 | b = 151.059 | c = 95.628 | (Ångstroms) |
 = 90.00 |  = 105.95 |  = 90.00 | (degrees) |
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| Refinement: | The structure was refined using the CNS 1.1 program.
The R value is
20.8
for 33180 reflections
in the resolution range 28.99 to
2.45 Ångstroms
with Fobs > 2.0 sigma(Fobs).
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