1 73 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 UGGCCGGCAU GGUCCCAGCC UCCUCGCUGG CGCCGGCUGG GCAACACCAU UGCACUCCGG UGGUGAAUGG GAC LOOP1 49 58 Crystallography ? ? Angstroms 1 U O3' -27.783 49.715 8.444 2 G P -27.441 48.160 8.711 O3' -25.573 47.609 14.055 3 G P -25.642 49.159 14.457 O3' -21.511 51.326 16.927 4 C P -21.893 52.884 16.907 O3' -18.662 56.719 15.691 5 C P -19.298 58.145 15.261 O3' -16.136 61.423 12.706 6 G P -16.793 62.760 12.118 O3' -15.100 65.846 8.507 7 G P -16.147 67.039 8.214 O3' -16.796 69.522 4.216 8 C P -17.987 70.500 4.682 O3' -21.408 72.018 0.993 9 A P -22.620 72.827 1.670 O3' -27.244 72.654 -0.699 10 U P -28.099 73.642 0.238 O3' -32.915 72.711 1.632 11 G P -33.129 74.215 2.151 O3' -35.368 71.465 6.518 12 G P -36.083 70.059 6.852 O3' -38.567 68.809 10.833 13 U P -38.843 67.242 10.605 O3' -42.601 65.090 13.396 14 C P -42.908 63.535 13.112 O3' -48.204 61.708 11.731 15 C P -48.199 60.177 11.250 O3' -52.094 58.375 8.191 16 C P -51.727 56.925 7.598 O3' -53.161 54.948 3.369 17 A P -52.483 53.492 3.383 O3' -50.739 51.336 -1.288 18 G P -49.734 50.093 -1.129 O3' -45.671 49.051 -4.452 19 C P -44.903 47.736 -3.922 O3' -39.654 47.479 -4.587 20 C P -38.992 46.166 -3.933 O3' -34.220 46.082 -2.113 21 U P -33.990 44.525 -1.802 O3' -30.106 44.170 2.574 22 C P -28.924 43.112 2.342 O3' -31.082 40.426 6.028 23 C P -31.457 41.672 6.956 O3' -30.078 43.296 12.339 24 U P -31.267 44.317 11.974 O3' -36.430 42.295 13.424 25 C P -37.740 42.905 12.735 O3' -42.093 42.440 9.714 26 G P -42.988 42.176 11.024 O3' -46.069 46.812 8.901 27 C P -46.969 46.610 10.231 O3' -45.925 51.122 13.773 28 U P -46.627 52.053 14.885 O3' -41.505 53.397 14.760 29 G P -40.156 52.581 15.089 O3' -36.658 54.099 11.201 30 G P -36.876 55.572 10.595 O3' -33.844 56.270 6.175 31 C P -34.200 57.652 5.448 O3' -34.187 58.371 0.305 32 G P -34.767 59.864 0.169 O3' -30.139 60.328 -2.546 33 C P -29.007 59.202 -2.721 O3' -24.715 60.349 -5.183 34 C P -23.885 58.978 -5.103 O3' -18.712 58.804 -4.742 35 G P -18.200 57.300 -4.505 O3' -13.843 56.141 -1.827 36 G P -13.650 54.599 -1.378 O3' -10.863 52.861 2.571 37 C P -11.128 51.319 2.938 O3' -9.939 49.322 7.458 38 U P -10.146 47.749 7.218 O3' -12.476 45.000 11.008 39 G P -12.677 43.486 10.514 O3' -15.046 40.244 13.855 40 G P -15.295 38.807 13.177 O3' -19.221 35.981 14.898 41 G P -18.935 34.551 14.221 O3' -22.578 31.648 12.229 42 C P -21.528 30.478 11.909 O3' -25.588 28.801 8.528 43 A P -26.201 27.506 9.255 O3' -30.792 28.010 8.051 44 A P -30.873 27.876 6.452 O3' -34.101 29.994 3.373 45 C P -33.683 29.382 1.953 O3' -32.894 31.693 -2.403 46 A P -32.174 30.606 -3.336 O3' -28.994 32.177 -7.172 47 C P -28.445 30.850 -7.865 O3' -23.549 30.768 -9.672 48 C P -23.082 29.314 -10.162 O3' -18.392 27.170 -9.754 49 A P -18.500 25.619 -10.179 O3' -15.978 21.676 -8.074 50 U P -16.608 20.373 -8.759 O3' -17.444 16.088 -6.080 51 U P -17.926 15.106 -7.263 O3' -19.956 10.272 -6.414 52 G P -18.695 9.418 -5.920 O3' -18.507 9.059 -0.512 53 C P -18.871 7.521 -0.214 O3' -19.151 6.985 4.142 54 A P -19.060 6.314 5.595 O3' -21.119 9.318 9.305 55 C P -20.776 8.836 10.787 O3' -23.943 8.628 14.906 56 U P -22.538 8.782 15.687 O3' -22.856 14.232 14.009 57 C P -24.386 14.530 13.663 O3' -24.519 18.720 11.247 58 C P -23.750 18.303 9.897 O3' -20.394 21.471 7.527 59 G P -19.617 20.790 6.302 O3' -16.434 25.448 5.221 60 G P -16.864 26.943 5.628 O3' -14.725 30.776 2.823 61 U P -15.247 32.166 3.417 O3' -16.258 36.214 0.214 62 G P -16.917 37.414 1.064 O3' -20.238 40.723 -1.486 63 G P -20.723 41.875 -0.472 O3' -25.804 44.355 -0.695 64 U P -26.012 45.082 -2.097 O3' -23.731 47.456 0.718 65 G P -22.918 48.810 1.057 O3' -25.606 49.505 -2.910 66 A P -26.029 51.054 -2.707 O3' -31.309 50.311 -4.233 67 A P -31.473 51.744 -4.914 O3' -36.631 53.086 -5.024 68 U P -36.311 54.382 -5.920 O3' -38.127 59.274 -6.906 69 G P -38.709 60.748 -7.210 O3' -44.102 62.769 -6.936 70 G P -44.620 64.210 -6.458 O3' -49.684 64.664 -5.103 71 G P -49.737 66.216 -4.683 O3' -53.274 67.982 -0.785 72 A P -53.172 69.452 -0.137 O3' -55.166 70.800 4.415 73 C P -54.926 72.348 4.800 O3' -52.351 74.500 9.603 26 syn 2 38 W W c 3 37 + + c 4 36 + + c 5 35 + + c 6 34 + + c 7 33 + + c 8 32 + + c 12 73 + + c 13 72 - - c 14 71 + + c 15 70 + + c 16 69 + + c 17 68 - - c 18 31 + + c 19 30 + + c 20 29 + + c 21 26 W H t 22 40 + + c 22 43 S W c 23 39 + + c 30 67 S S t 41 43 S H c 42 62 W H t 44 63 W W c 45 62 + + c 46 61 - - c 47 60 + + c 48 59 + + c 41 63 ! ! ! 42 44 ! ! ! 42 45 ! ! ! 56 58 ! ! ! 1 3 ! ! ! 1 4 ! ! ! 1 64 ! ! ! 19 67 ! ! ! 20 66 ! ! ! 53 54 ! ! ! 56 57 ! ! ! 2 38 7 22 40 2 44 63 5 12 73 6 18 31 3 SG1 1 1 SG2 9 11 SG3 21 21 SG4 24 28 SG5 41 43 SG6 49 58 SG7 64 67 1 104.034 270.294 2 91.030 270.294 3 91.030 248.620 4 91.030 226.946 5 91.030 205.273 6 91.030 183.599 7 91.030 161.925 8 91.030 140.251 9 91.030 127.247 10 91.030 114.243 11 91.030 101.239 12 130.555 13.270 13 136.084 34.227 14 141.613 55.183 15 147.142 76.140 16 152.672 97.096 17 158.201 118.053 18 169.259 159.966 19 174.788 180.923 20 180.317 201.879 21 104.034 335.315 22 91.030 335.315 23 91.030 313.641 24 104.034 313.641 25 117.038 313.641 26 130.042 313.641 27 143.047 313.641 28 156.051 313.641 29 230.613 188.609 30 225.084 167.653 31 219.555 146.696 32 39.013 140.251 33 39.013 161.925 34 39.013 183.599 35 39.013 205.273 36 39.013 226.946 37 39.013 248.620 38 39.013 270.294 39 39.013 313.641 40 39.013 335.315 41 26.008 335.315 42 13.004 335.315 43 0.000 335.315 44 39.013 378.663 45 39.013 400.336 46 39.013 422.010 47 39.013 443.684 48 39.013 465.358 49 24.297 481.134 50 18.203 501.829 51 22.021 523.063 52 34.944 540.339 53 54.234 550.000 54 75.808 550.000 55 95.099 540.339 56 108.021 523.063 57 111.840 501.829 58 105.746 481.134 59 91.030 465.358 60 91.030 443.684 61 91.030 422.010 62 91.030 400.336 63 91.030 378.663 64 104.034 378.663 65 117.038 378.663 66 130.042 378.663 67 143.047 378.663 68 208.497 104.783 69 202.967 83.826 70 197.438 62.870 71 191.909 41.913 72 186.380 20.957 73 180.851 0.000