 |  |  |  |
| Title: |  | CRYSTAL STRUCTURE OF THE HEPATITIS DELTA VIRUS GEMONIC RIBOZYME PRECURSOR, WITH C75U MUTAION, AND MN2+ BOUND |  |
 |
| Molecular Description: | PROTEIN/RNA Complex |
 |
| Structural Features: | SINGLE STRAND, hairpin loop |
 |
| Nucleic Acid Sequence: |
 |  |  |  |
| Chain | B: | | G A U G G C C G G C A U G G U C C C A G C C U C C U C G C U G G C G C C G G C U G G G C A A C A C C A U U G C A C U C C G G U G G U G A A U G G G A C U |
|
 |
| Protein Sequence: |
|
 |
| Primary Citation: | Ke, A., Zhou, K., Ding, F., Cate, J.H.D., Doudna, J.A.
A Conformational Switch controls hepatitis delta virus ribozyme catalysis
NATURE
, 429,
pp. 201 - 205, 2004.
|
 |
 |  |  |  |
| Experimental Information: | X-RAY DIFFRACTION |
 |
| Space Group: |
H
3
2
|
 |
| Cell Constants: |
| a = 108.589 | b = 108.589 | c = 190.519 | (Ångstroms) |
= 90.00 | = 90.00 | = 120.00 | (degrees) |
|
 |
| Refinement: | The structure was refined using the CNS 1.1 program.
The R value is
23.9
for 9690 reflections
in the resolution range 42.16 to
2.90 Ångstroms
with Fobs > 0.0 sigma(Fobs).
|
|
|