1 74 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 AUGGCCGGCA UGGUCCCAGC CUCCUCGCUG GCGCCGGCUG GGCAACACCA UUGCACUCCG GUGGUGAAUG GGAC LOOP1 50 59 Crystallography ? ? Angstroms 1 A O3' -64.158 53.551 87.952 2 U P -65.513 52.800 88.359 O3' -62.210 48.410 88.402 3 G P -61.828 47.014 89.068 O3' -61.440 46.937 94.276 4 G P -61.145 48.472 94.634 O3' -57.576 51.240 97.029 5 C P -57.749 52.793 96.615 O3' -54.298 56.342 95.603 6 C P -54.768 57.758 94.988 O3' -51.474 61.376 93.267 7 G P -52.182 62.634 92.562 O3' -50.090 65.422 88.817 8 G P -51.090 66.634 88.468 O3' -51.409 69.012 84.272 9 C P -52.608 69.989 84.696 O3' -55.781 71.613 80.877 10 A P -56.939 72.565 81.455 O3' -61.511 72.490 79.339 11 U P -62.221 73.701 80.100 O3' -67.320 72.823 81.216 12 G P -67.660 74.354 81.551 O3' -69.628 72.131 86.213 13 G P -70.242 70.707 86.647 O3' -72.732 69.539 90.784 14 U P -73.041 67.975 90.571 O3' -76.858 66.133 93.541 15 C P -77.240 64.584 93.380 O3' -82.399 62.279 92.053 16 C P -82.510 60.829 91.393 O3' -86.463 59.102 88.758 17 C P -86.001 57.632 88.305 O3' -87.430 55.296 84.123 18 A P -86.659 53.897 84.217 O3' -85.332 51.815 79.289 19 G P -84.414 50.506 79.349 O3' -80.669 49.419 75.839 20 C P -80.018 48.045 76.386 O3' -74.771 47.555 75.698 21 C P -74.100 46.287 76.430 O3' -69.366 46.176 78.002 22 U P -69.136 44.615 78.298 O3' -65.397 43.629 82.611 23 C P -64.289 42.547 82.196 O3' -66.295 40.192 86.073 24 C P -66.545 41.343 87.162 O3' -64.677 42.158 92.547 25 U P -65.075 43.648 92.973 O3' -70.696 42.237 93.208 26 C P -72.003 42.697 92.399 O3' -76.903 42.562 90.633 27 G P -77.831 42.336 91.930 O3' -80.864 46.967 89.780 28 C P -81.497 47.052 91.270 O3' -80.165 51.831 94.325 29 U P -80.647 52.779 95.534 O3' -75.426 53.235 95.139 30 G P -74.349 52.136 95.613 O3' -70.965 53.989 91.533 31 G P -71.135 55.449 90.873 O3' -68.535 56.476 86.263 32 C P -68.883 57.801 85.412 O3' -69.010 58.233 80.283 33 G P -69.586 59.691 79.982 O3' -65.099 60.649 77.487 34 C P -64.014 59.489 77.215 O3' -59.517 60.201 74.983 35 C P -58.603 58.887 75.165 O3' -53.515 58.812 75.749 36 G P -52.900 57.379 76.120 O3' -48.837 56.120 78.594 37 G P -48.816 54.528 78.834 O3' -45.883 52.723 83.104 38 C P -46.008 51.304 83.847 O3' -45.259 49.321 87.982 39 U P -45.435 47.810 87.461 O3' -47.082 44.215 91.117 40 G P -47.668 42.773 90.696 O3' -50.173 39.835 93.912 41 G P -50.410 38.431 93.169 O3' -54.499 35.403 94.598 42 G P -54.128 34.025 93.861 O3' -57.750 31.081 91.572 43 C P -56.601 29.972 91.434 O3' -60.817 28.418 88.479 44 A P -61.489 27.116 89.141 O3' -66.216 27.916 88.241 45 A P -66.202 27.569 86.672 O3' -69.545 29.696 83.453 46 C P -69.094 28.969 82.091 O3' -68.392 31.487 77.578 47 A P -67.749 30.242 76.792 O3' -64.384 31.456 73.105 48 C P -63.843 30.104 72.461 O3' -58.987 29.851 70.519 49 C P -58.577 28.353 70.118 O3' -53.725 26.515 70.432 50 A P -53.899 25.001 69.889 O3' -51.254 21.128 72.109 51 U P -51.864 19.811 71.425 O3' -52.579 15.485 74.273 52 U P -53.008 14.425 73.146 O3' -55.058 9.608 73.927 53 G P -53.763 8.819 74.444 O3' -53.539 8.408 79.913 54 C P -54.017 6.957 80.425 O3' -54.442 6.913 84.990 55 A P -54.254 5.977 86.281 O3' -56.210 9.242 90.128 56 C P -55.811 8.750 91.593 O3' -59.082 8.518 95.732 57 U P -57.708 8.951 96.437 O3' -57.983 14.212 94.100 58 C P -59.516 14.573 93.796 O3' -59.761 18.586 91.366 59 C P -58.899 18.305 90.046 O3' -55.453 21.135 87.521 60 G P -54.582 20.435 86.364 O3' -51.272 25.103 85.494 61 G P -51.775 26.581 85.870 O3' -50.013 30.462 82.681 62 U P -50.567 31.840 83.309 O3' -51.691 35.855 80.014 63 G P -52.402 37.103 80.759 O3' -55.823 40.179 78.336 64 G P -56.052 41.379 79.374 O3' -60.521 44.406 79.207 65 U P -61.438 44.774 77.917 O3' -59.358 47.050 80.556 66 G P -58.367 48.117 81.221 O3' -60.829 49.031 77.352 67 A P -60.992 50.596 76.974 O3' -66.362 50.277 75.658 68 A P -66.515 51.672 74.909 O3' -71.517 52.948 74.931 69 U P -71.387 54.391 74.223 O3' -73.194 59.192 73.667 70 G P -73.699 60.665 73.273 O3' -78.913 63.153 73.359 71 G P -79.299 64.644 73.802 O3' -84.540 65.405 75.005 72 G P -84.940 66.818 75.676 O3' -88.103 68.086 79.581 73 A P -87.966 69.547 80.247 O3' -89.673 71.024 84.645 74 C P -89.504 72.600 84.869 O3' -86.849 75.468 89.193 25 syn 27 syn 3 39 W W c 4 38 + + c 5 37 + + c 5 38 W W c 6 36 + + c 7 35 + + c 8 34 + + c 9 33 + + c 13 74 + + c 14 73 - - c 15 72 + + c 16 71 + + c 17 70 + + c 18 69 - - c 19 32 + + c 20 31 + + c 21 30 + + c 22 27 W H t 23 41 + + c 23 44 S W c 24 40 + + c 31 68 S S t 42 44 S H c 43 63 W H t 45 64 W W c 46 63 + + c 47 62 - - c 48 61 + + c 49 60 + + c 57 59 S H c 42 45 ! ! ! 42 64 ! ! ! 43 46 ! ! ! 2 31 ! ! ! 2 4 ! ! ! 2 65 ! ! ! 21 67 ! ! ! 53 54 ! ! ! 3 39 7 23 41 2 45 64 5 13 74 6 19 32 3 SG1 1 2 SG2 10 12 SG3 22 22 SG4 25 29 SG5 42 44 SG6 50 59 SG7 65 68 1 116.695 271.114 2 103.729 271.114 3 90.763 271.114 4 90.763 249.504 5 90.763 227.893 6 90.763 206.283 7 90.763 184.673 8 90.763 163.063 9 90.763 141.453 10 90.763 128.486 11 90.763 115.520 12 90.763 102.554 13 126.062 12.596 14 131.310 33.559 15 136.559 54.522 16 141.807 75.485 17 147.055 96.449 18 152.303 117.412 19 162.800 159.338 20 168.048 180.302 21 173.296 201.265 22 103.729 335.944 23 90.763 335.944 24 90.763 314.334 25 103.729 314.334 26 116.695 314.334 27 129.661 314.334 28 142.627 314.334 29 155.594 314.334 30 223.608 188.669 31 218.360 167.706 32 213.111 146.743 33 38.898 141.453 34 38.898 163.063 35 38.898 184.673 36 38.898 206.283 37 38.898 227.893 38 38.898 249.504 39 38.898 271.114 40 38.898 314.334 41 38.898 335.944 42 25.932 335.944 43 12.966 335.944 44 0.000 335.944 45 38.898 379.165 46 38.898 400.775 47 38.898 422.385 48 38.898 443.995 49 38.898 465.606 50 24.225 481.336 51 18.149 501.971 52 21.957 523.142 53 34.841 540.368 54 54.075 550.000 55 75.586 550.000 56 94.820 540.368 57 107.705 523.142 58 111.512 501.971 59 105.436 481.336 60 90.763 465.606 61 90.763 443.995 62 90.763 422.385 63 90.763 400.775 64 90.763 379.165 65 103.729 379.165 66 116.695 379.165 67 129.661 379.165 68 142.627 379.165 69 202.615 104.816 70 197.367 83.853 71 192.119 62.890 72 186.870 41.926 73 181.622 20.963 74 176.374 0.000