1 73 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 UGGCCGGCAU GGUCCCAGCC UCCUCGCUGG CGCCGGCUGG GCAACACCAU UGCACUCCGG UGGUGAAUGG GAC LOOP1 49 58 Crystallography ? ? Angstroms 1 U O3' -63.188 47.938 89.492 2 G P -62.745 46.400 89.723 O3' -60.860 45.789 95.037 3 G P -60.779 47.341 95.434 O3' -56.692 49.455 97.836 4 C P -57.072 51.012 97.732 O3' -53.839 54.781 96.699 5 C P -54.506 56.201 96.320 O3' -51.371 59.695 93.694 6 G P -51.931 61.032 93.002 O3' -50.282 63.968 89.497 7 G P -51.428 65.092 89.384 O3' -52.289 67.562 85.202 8 C P -53.490 68.523 85.673 O3' -56.733 69.921 81.725 9 A P -57.894 70.857 82.321 O3' -62.622 70.712 80.402 10 U P -63.421 71.797 81.278 O3' -68.306 70.989 82.706 11 G P -68.482 72.545 83.064 O3' -70.751 69.708 87.579 12 G P -71.446 68.257 87.708 O3' -73.890 66.927 92.016 13 U P -74.318 65.378 91.871 O3' -78.341 63.821 94.733 14 C P -78.384 62.229 94.506 O3' -83.481 60.386 92.939 15 C P -83.564 58.841 92.522 O3' -87.306 56.855 89.611 16 C P -86.780 55.401 89.177 O3' -88.341 53.152 84.790 17 A P -87.558 51.747 84.683 O3' -86.182 49.835 79.830 18 G P -85.259 48.533 80.016 O3' -81.250 47.200 76.809 19 C P -80.481 45.933 77.449 O3' -75.312 45.631 76.752 20 C P -74.687 44.315 77.447 O3' -69.881 44.214 79.027 21 U P -69.608 42.669 79.383 O3' -65.920 42.139 83.847 22 C P -64.621 41.301 83.438 O3' -66.484 38.555 87.165 23 C P -66.856 39.807 88.099 O3' -65.356 41.222 93.588 24 U P -66.573 42.245 93.398 O3' -71.867 40.846 94.799 25 C P -73.044 41.293 93.813 O3' -77.417 40.799 91.194 26 G P -78.343 40.534 92.486 O3' -81.497 45.102 90.384 27 C P -82.389 44.803 91.703 O3' -81.354 49.252 95.309 28 U P -81.919 50.261 96.429 O3' -76.685 51.582 96.027 29 G P -75.252 50.953 96.413 O3' -71.990 52.836 92.311 30 G P -72.254 54.229 91.544 O3' -69.327 54.797 87.039 31 C P -69.744 56.126 86.230 O3' -69.899 56.450 80.976 32 G P -70.356 57.987 80.864 O3' -65.723 58.659 78.676 33 C P -64.511 57.635 78.385 O3' -60.301 58.759 75.785 34 C P -59.481 57.377 75.834 O3' -54.273 57.246 76.395 35 G P -53.589 55.827 76.706 O3' -49.484 54.606 79.373 36 G P -49.330 53.042 79.725 O3' -46.162 51.215 83.466 37 C P -46.300 49.667 83.880 O3' -45.488 47.227 88.255 38 U P -45.882 45.702 87.922 O3' -47.976 42.840 91.838 39 G P -48.477 41.344 91.523 O3' -50.673 38.443 94.947 40 G P -50.770 37.017 94.214 O3' -54.853 34.070 95.668 41 G P -54.475 32.661 94.987 O3' -58.049 29.642 92.818 42 C P -56.899 28.528 92.608 O3' -60.936 26.982 89.432 43 A P -61.508 25.716 90.237 O3' -66.304 26.217 89.383 44 A P -66.463 25.973 87.805 O3' -69.772 28.031 84.720 45 C P -69.346 27.431 83.296 O3' -68.957 29.825 78.886 46 A P -68.293 28.706 77.938 O3' -65.029 29.959 74.172 47 C P -64.432 28.626 73.504 O3' -59.576 28.604 71.388 48 C P -59.188 27.099 70.985 O3' -54.496 25.146 71.197 49 A P -54.605 23.593 70.768 O3' -52.000 19.724 72.983 50 U P -52.591 18.394 72.308 O3' -53.354 14.087 75.073 51 U P -53.846 13.030 73.972 O3' -55.752 8.199 74.630 52 G P -54.520 7.466 75.341 O3' -54.181 7.093 80.665 53 C P -54.635 5.613 81.060 O3' -54.695 5.148 85.510 54 A P -54.554 4.445 86.954 O3' -56.758 7.641 90.646 55 C P -56.239 7.225 92.101 O3' -59.482 6.730 96.337 56 U P -58.132 7.061 97.140 O3' -58.259 12.572 95.248 57 C P -59.685 12.857 94.562 O3' -60.243 16.991 92.412 58 C P -59.483 16.627 91.046 O3' -56.028 19.689 88.617 59 G P -55.184 19.032 87.415 O3' -51.893 23.658 86.204 60 G P -52.301 25.156 86.603 O3' -50.487 28.889 83.466 61 U P -51.073 30.261 84.073 O3' -52.123 34.362 80.888 62 G P -52.837 35.576 81.683 O3' -56.247 38.674 79.295 63 G P -56.530 39.860 80.340 O3' -61.936 42.221 80.122 64 U P -62.258 43.142 78.847 O3' -60.169 45.514 81.407 65 G P -59.019 46.461 81.982 O3' -61.493 47.479 78.100 66 A P -61.727 49.067 77.879 O3' -66.941 48.494 76.360 67 A P -67.235 49.914 75.699 O3' -72.284 50.975 75.987 68 U P -72.178 52.350 75.167 O3' -73.725 57.234 74.303 69 G P -74.222 58.730 73.970 O3' -79.571 61.100 74.127 70 G P -80.115 62.511 74.680 O3' -84.978 63.395 76.124 71 G P -85.145 64.863 76.771 O3' -88.841 65.909 80.433 72 A P -88.748 67.440 80.919 O3' -90.325 68.952 85.615 73 C P -90.103 70.521 85.880 O3' -87.644 73.135 90.480 26 syn 2 38 W W c 3 37 + + c 4 36 + + c 5 35 + + c 6 34 + + c 7 33 + + c 8 32 + + c 12 73 + + c 13 72 - - c 14 71 + + c 15 70 + + c 16 69 + + c 17 68 - - c 18 31 + + c 19 30 + + c 20 29 + + c 21 26 W H t 22 40 + + c 22 43 S W c 23 39 + + c 30 67 S S t 41 43 S H c 42 62 W H t 44 63 W W c 45 62 + + c 46 61 - - c 47 60 + + c 48 59 + + c 56 57 S H c 4 37 ! ! ! 41 44 ! ! ! 41 63 ! ! ! 42 45 ! ! ! 1 3 ! ! ! 1 4 ! ! ! 19 67 ! ! ! 20 66 ! ! ! 52 53 ! ! ! 64 65 ! ! ! 2 38 7 22 40 2 44 63 5 12 73 6 18 31 3 SG1 1 1 SG2 9 11 SG3 21 21 SG4 24 28 SG5 41 43 SG6 49 58 SG7 64 67 1 103.753 271.049 2 90.784 271.049 3 90.784 249.434 4 90.784 227.819 5 90.784 206.203 6 90.784 184.588 7 90.784 162.973 8 90.784 141.358 9 90.784 128.389 10 90.784 115.420 11 90.784 102.450 12 128.682 13.624 13 134.358 34.480 14 140.035 55.337 15 145.712 76.193 16 151.388 97.050 17 157.065 117.906 18 168.418 159.619 19 174.095 180.476 20 179.771 201.332 21 103.753 335.895 22 90.784 335.895 23 90.784 314.280 24 103.753 314.280 25 116.722 314.280 26 129.691 314.280 27 142.660 314.280 28 155.630 314.280 29 229.827 187.709 30 224.150 166.852 31 218.474 145.996 32 38.907 141.358 33 38.907 162.973 34 38.907 184.588 35 38.907 206.203 36 38.907 227.819 37 38.907 249.434 38 38.907 271.049 39 38.907 314.280 40 38.907 335.895 41 25.938 335.895 42 12.969 335.895 43 0.000 335.895 44 38.907 379.125 45 38.907 400.740 46 38.907 422.356 47 38.907 443.971 48 38.907 465.586 49 24.231 481.320 50 18.153 501.960 51 21.962 523.136 52 34.849 540.365 53 54.088 550.000 54 75.604 550.000 55 94.842 540.365 56 107.730 523.136 57 111.538 501.960 58 105.460 481.320 59 90.784 465.586 60 90.784 443.971 61 90.784 422.356 62 90.784 400.740 63 90.784 379.125 64 103.753 379.125 65 116.722 379.125 66 129.691 379.125 67 142.660 379.125 68 207.120 104.283 69 201.444 83.426 70 195.767 62.570 71 190.091 41.713 72 184.414 20.857 73 178.737 0.000