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| Title: | | CRYSTAL STRUCTURE OF A C75U MUTANT HEPATITIS DELTA VIRUS RIBOZYME PRECURSOR, IN CU2+ SOLUTION | |
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| Molecular Description: |
small nuclear ribonucleoprotein A/precursor form of the Hepatitis Delta virus ribozyme complex |
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| Structural Features: | SINGLE STRAND, loops, bulges, BASE TRIPLET,FLIPPED-OUT BASES |
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| Nucleic Acid Sequence: |
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| Chain | R: | | G A U G G C C G G C A U G G U C C C A G C C U C C U C G C U G G C G C C G G C U G G G C A A C A C C A U U G C A C U C C G G U G G U G A A U G G G A C U |
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| Protein Sequence: |
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| Primary Citation: | Ke, A., Zhou, K., Ding, F., Cate, J.H., Doudna, J.A.
A Conformational Switch controls hepatitis delta virus ribozyme catalysis
Nature
, 429,
pp. 201 - 205, 2004.
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| Experimental Information: | X-RAY DIFFRACTION |
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| Space Group: |
H
3
2
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| Cell Constants: |
| a = 108.566 | b = 108.566 | c = 190.319 | (Ångstroms) |
 = 90.00 |  = 90.00 |  = 120.00 | (degrees) |
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| Refinement: | The structure was refined using the CNS 1.1 program.
The R value is
25.0
for 12008 reflections
in the resolution range 35.28 to
2.70 Ångstroms
with Fobs > 2.0 sigma(Fobs).
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