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| Title: | | FOOT AND MOUTH DISEASE VIRUS RNA-DEPENDENT RNA POLYMERASE IN COMPLEX WITH A TEMPLATE-PRIMER RNA | |
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| Molecular Description: |
RNA-dependent RNA polymerase(E.C.2.7.7.48)/5'-R(
CpApUpGpGpGpCpC)-3'/5'-R(GpGpCpCpC)-3' |
 |
| Structural Features: | RH DOUBLE HELIX, OVERHANGING BASES |
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| Nucleic Acid Sequence: |
| | | |
| Chain | B: | | C A U G G G C C |
| Chain | C: | | G G C C C |
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| Protein Sequence: |
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| Primary Citation: | Ferrer-Orta, C., Arias, A., Perez-Luque, R., Escarmis, C., Domingo, E., Verdaguer, N.
Structure of Foot-and-Mouth Disease Virus RNA-dependent RNA Polymerase and Its Complex with a Template-Primer RNA
J.Biol.Chem.
, 279,
pp. 47212 - 47221, 2004.
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| Experimental Information: | X-RAY DIFFRACTION |
|
| Space Group: |
P
32
2
1
|
|
| Cell Constants: |
| a = 94.627 | b = 94.627 | c = 100.513 | (Ångstroms) |
 = 90.00 |  = 90.00 |  = 120.00 | (degrees) |
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| Refinement: | The structure was refined using the CNS 1.1 program.
The R value is
27.3
for 10479 reflections
in the resolution range 19.52 to
3.00 Ångstroms
with Fobs > 2.0 sigma(Fobs).
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