1 22 13 14 15 16 17 18 19 20 21 22 23 24 25 27 28 29 30 31 32 33 34 35 GGCGUUGCCG GUCGGCAACG CC LOOP1 11 12 Crystallography ? ? Angstroms 1 G O3' 13.015 53.319 16.606 2 G P 13.655 53.586 15.155 O3' 16.101 58.061 14.483 3 C P 16.578 57.924 12.950 O3' 21.190 59.985 11.531 4 G P 21.414 59.463 10.022 O3' 26.519 58.789 8.662 5 U P 26.600 58.314 7.118 O3' 30.534 55.298 5.601 6 U P 30.175 54.918 4.080 O3' 31.626 50.159 2.449 7 G P 30.941 49.920 1.019 O3' 29.941 45.181 -0.648 8 C P 29.176 45.374 -2.038 O3' 25.674 41.896 -3.555 9 C P 24.915 42.535 -4.813 O3' 19.872 41.248 -5.459 10 G P 19.705 41.761 -6.966 O3' 15.557 44.178 -8.741 11 G P 16.061 44.867 -10.100 O3' 13.505 50.252 -9.537 12 U P 13.626 50.913 -8.058 O3' 14.734 56.209 -8.580 13 C P 14.695 57.603 -7.731 O3' 14.211 58.397 -1.946 14 G O3' 12.882 51.018 3.152 15 G P 13.350 50.580 4.625 O3' 13.639 45.478 5.376 16 C P 14.189 45.460 6.879 O3' 17.462 41.756 8.315 17 A P 18.023 42.161 9.767 O3' 22.699 40.542 11.136 18 A P 23.473 41.072 12.444 O3' 28.546 42.648 13.637 19 C P 28.299 43.041 15.169 O3' 31.601 46.908 16.505 20 G P 31.193 47.563 17.915 O3' 31.730 52.207 19.321 21 C P 31.115 52.088 20.801 O3' 28.885 56.631 22.349 22 C P 28.222 56.489 23.806 O3' 24.166 58.554 25.643 18 syn 1 22 + + c 2 21 + + c 3 20 + + c 4 19 + + c 5 18 W H c 6 17 - - c 7 16 + + c 8 15 + + c 9 14 + + c 10 13 + + c 4 18 ! ! ! 1 22 10 SG1 11 12 1 230.033 330.995 2 207.817 329.843 3 185.602 328.692 4 163.387 327.540 5 141.171 326.388 6 118.956 325.237 7 96.741 324.085 8 74.525 322.933 9 52.310 321.782 10 30.095 320.630 11 0.000 308.572 12 1.678 276.195 13 32.859 267.313 14 55.074 268.465 15 77.289 269.616 16 99.505 270.768 17 121.720 271.920 18 143.935 273.071 19 166.151 274.223 20 188.366 275.375 21 210.581 276.526 22 232.797 277.678 1 22 13 14 15 16 17 18 19 20 21 22 23 24 25 27 28 29 30 31 32 33 34 35 GGCGUUGC CGGUCGGCAA CGCC LOOP2 11 12 Crystallography ? ? Angstroms 1 G O3' 45.248 7.399 14.903 2 G P 45.699 7.808 13.414 O3' 45.346 5.183 9.279 3 C P 45.843 6.270 8.204 O3' 43.850 5.982 3.342 4 G P 44.324 7.299 2.551 O3' 40.914 9.376 -1.000 5 U P 41.566 10.671 -1.707 O3' 38.923 14.593 -3.658 6 U P 40.026 15.705 -4.014 O3' 38.910 20.706 -3.742 7 G P 40.248 21.521 -4.110 O3' 40.994 26.218 -2.171 8 C P 42.464 26.575 -2.692 O3' 45.453 29.792 0.112 9 C P 46.911 29.678 -0.532 O3' 50.897 30.119 2.781 10 G P 52.103 30.295 1.744 O3' 56.759 28.309 2.026 11 G P 57.354 28.555 0.567 O3' 59.940 23.212 -0.297 12 U P 59.072 21.907 0.122 O3' 59.559 18.060 -3.669 13 C P 59.270 16.461 -3.773 O3' 55.815 13.027 -0.431 14 G O3' 53.058 16.411 7.825 15 G P 51.682 16.472 8.650 O3' 49.915 20.224 11.512 16 C P 48.482 19.682 11.992 O3' 44.450 22.593 12.817 17 A P 43.195 21.628 13.066 O3' 38.552 22.987 11.979 18 A P 37.330 21.957 12.087 O3' 32.830 20.836 9.011 19 C P 32.174 19.587 9.764 O3' 29.956 16.326 6.372 20 G P 29.496 15.063 7.257 O3' 29.006 10.436 5.393 21 C P 28.571 9.602 6.693 O3' 30.231 4.532 6.690 22 C P 29.836 3.751 8.039 O3' 32.563 0.267 10.649 18 syn 1 22 + + c 2 21 + + c 3 20 + + c 4 19 + + c 5 18 W H c 6 17 - - c 7 16 + + c 8 15 + + c 9 14 + + c 10 13 + + c 1 22 10 SG1 11 12 1 550.000 159.092 2 550.000 181.338 3 550.000 203.583 4 550.000 225.828 5 550.000 248.073 6 550.000 270.318 7 550.000 292.563 8 550.000 314.809 9 550.000 337.054 10 550.000 359.299 11 539.516 389.977 12 507.096 389.977 13 496.612 359.299 14 496.612 337.054 15 496.612 314.809 16 496.612 292.563 17 496.612 270.318 18 496.612 248.073 19 496.612 225.828 20 496.612 203.583 21 496.612 181.338 22 496.612 159.092 1 21 13 14 15 16 17 18 19 20 21 22 23 24 27 28 29 30 31 32 33 34 35 GGCGUU GCCGGUGGCA ACGCC LOOP3 10 12 Crystallography ? ? Angstroms 1 G O3' 13.239 36.161 -6.846 2 G P 13.105 36.258 -5.251 O3' 15.404 39.362 -2.162 3 C P 14.992 38.566 -0.827 O3' 13.549 41.410 3.398 4 G P 12.982 40.523 4.615 O3' 9.631 42.895 7.969 5 U P 9.160 41.822 9.066 O3' 4.456 41.996 11.404 6 U P 4.275 40.660 12.283 O3' -0.231 38.035 12.784 7 G P -0.108 36.612 13.524 O3' -3.150 32.581 12.767 8 C P -2.499 31.388 13.621 O3' -3.207 26.512 12.182 9 C P -2.218 25.627 13.090 O3' -0.046 21.367 11.142 10 G P 0.205 20.732 12.595 O3' 4.803 18.004 13.275 11 G P 5.086 17.831 14.849 O3' 10.576 19.467 15.478 12 U P 11.120 20.456 14.321 O3' 14.726 23.718 16.570 13 G O3' 12.332 27.146 4.277 14 G P 11.210 27.683 3.257 O3' 7.440 25.781 0.890 15 C P 6.951 27.069 0.058 O3' 1.917 27.501 -1.292 16 A P 1.763 28.891 -2.087 O3' -2.212 32.003 -1.398 17 A P -2.267 33.527 -1.894 O3' -4.934 38.127 -0.105 18 C P -4.622 39.087 -1.346 O3' -3.535 43.902 -0.128 19 G P -2.818 44.510 -1.426 O3' 0.518 48.436 -0.413 20 C P 1.051 49.004 -1.818 O3' 5.617 51.234 -2.436 21 C P 5.731 51.426 -4.028 O3' 10.626 51.206 -5.749 17 syn 1 21 + + c 2 20 + + c 3 19 + + c 4 18 + + c 5 17 W H c 6 16 - - c 7 15 + + c 8 14 + + c 9 13 + + c 1 21 9 SG1 10 12 1 73.464 141.476 2 93.135 131.088 3 112.806 120.700 4 132.477 110.312 5 152.147 99.925 6 171.818 89.537 7 191.489 79.149 8 211.160 68.761 9 230.831 58.373 10 254.521 43.474 11 254.872 15.490 12 231.563 0.000 13 205.900 11.163 14 186.229 21.551 15 166.558 31.939 16 146.888 42.327 17 127.217 52.715 18 107.546 63.103 19 87.875 73.490 20 68.204 83.878 21 48.533 94.266 10 1 ! ! ! 15 3 ! ! !