1 9 307 308 309 310 311 312 313 314 315 GUCUAAGAC LOOP1 4 6 LOOP2 4 6 LOOP3 4 6 LOOP4 4 6 LOOP5 4 6 LOOP6 4 6 LOOP7 4 6 LOOP8 4 6 LOOP9 4 6 LOOP10 4 6 LOOP11 4 6 LOOP12 4 6 LOOP13 4 6 LOOP14 4 6 LOOP15 4 6 LOOP16 4 6 LOOP17 4 6 LOOP18 4 6 LOOP19 4 6 LOOP20 4 6 LOOP21 4 6 LOOP22 4 6 LOOP23 4 6 LOOP24 4 6 LOOP25 4 6 LOOP26 4 6 LOOP27 4 6 LOOP28 4 6 LOOP29 4 6 LOOP30 4 6 LOOP31 4 6 LOOP32 4 6 LOOP33 4 6 LOOP34 4 6 LOOP35 4 6 LOOP36 4 6 LOOP37 4 6 LOOP38 4 6 LOOP39 4 6 LOOP40 4 6 LOOP41 4 6 LOOP42 4 6 LOOP43 4 6 LOOP44 4 6 LOOP45 4 6 LOOP46 4 6 LOOP47 4 6 LOOP48 4 6 LOOP49 4 6 LOOP50 4 6 LOOP51 4 6 LOOP52 4 6 LOOP53 4 6 LOOP54 4 6 LOOP55 4 6 LOOP56 4 6 LOOP57 4 6 LOOP58 4 6 LOOP59 4 6 LOOP60 4 6 Crystallography ? ? Angstroms 1 G P -57.835 34.309 84.395 O3' -56.176 38.615 82.190 2 U P -57.475 39.538 82.012 O3' -57.702 43.269 78.364 3 C P -59.105 44.015 78.557 O3' -61.778 45.982 74.571 4 U P -63.224 46.615 74.895 O3' -66.778 43.689 71.296 5 A P -68.310 44.049 71.644 O3' -70.667 39.134 73.615 6 A P -72.103 38.937 72.940 O3' -73.260 33.613 71.488 7 G P -72.967 33.540 69.921 O3' -68.301 33.382 67.486 8 A P -66.871 32.659 67.257 O3' -61.652 35.148 66.524 9 C P -60.926 33.724 66.489 O3' -55.793 34.150 67.036 1 9 + + c 2 8 - - c 3 7 + + c 4 5 ! ! ! 1 9 3 SG1 4 6 1 421.499 211.788 2 422.368 210.349 3 423.236 208.911 4 424.462 207.188 5 426.574 207.283 6 427.641 209.108 7 426.688 210.995 8 425.820 212.433 9 424.952 213.872 1 3 411 412 413 A AG Crystallography ? ? Angstroms 1 A P -91.745 20.659 51.166 O3' -89.738 22.536 56.359 2 A P -89.159 23.189 57.729 O3' -83.607 22.983 59.694 3 G P -82.090 23.014 59.152 O3' -79.997 21.367 53.551 SG1 1 3 1 426.092 550.000 2 426.092 550.000 3 426.092 550.000 1 9 307 308 309 310 311 312 313 314 315 GUCUAAGA C LOOP1 4 6 LOOP2 4 6 LOOP3 4 6 LOOP4 4 6 LOOP5 4 6 LOOP6 4 6 LOOP7 4 6 LOOP8 4 6 LOOP9 4 6 LOOP10 4 6 LOOP11 4 6 LOOP12 4 6 LOOP13 4 6 LOOP14 4 6 LOOP15 4 6 LOOP16 4 6 LOOP17 4 6 LOOP18 4 6 LOOP19 4 6 LOOP20 4 6 LOOP21 4 6 LOOP22 4 6 LOOP23 4 6 LOOP24 4 6 LOOP25 4 6 LOOP26 4 6 LOOP27 4 6 LOOP28 4 6 LOOP29 4 6 LOOP30 4 6 LOOP31 4 6 LOOP32 4 6 LOOP33 4 6 LOOP34 4 6 LOOP35 4 6 LOOP36 4 6 LOOP37 4 6 LOOP38 4 6 LOOP39 4 6 LOOP40 4 6 LOOP41 4 6 LOOP42 4 6 LOOP43 4 6 LOOP44 4 6 LOOP45 4 6 LOOP46 4 6 LOOP47 4 6 LOOP48 4 6 LOOP49 4 6 LOOP50 4 6 LOOP51 4 6 LOOP52 4 6 LOOP53 4 6 LOOP54 4 6 LOOP55 4 6 LOOP56 4 6 LOOP57 4 6 LOOP58 4 6 LOOP59 4 6 LOOP60 4 6 Crystallography ? ? Angstroms 1 G P -79.428 9.509 72.423 O3' -81.572 10.993 68.023 2 U P -82.936 10.159 67.904 O3' -85.169 9.212 63.278 3 C P -86.536 8.437 63.579 O3' -88.447 4.830 60.379 4 U P -89.778 4.056 60.853 O3' -88.194 -1.563 60.585 5 A P -89.349 -2.478 61.239 O3' -86.990 -4.827 65.984 6 A P -87.368 -6.380 66.041 O3' -83.171 -9.715 67.791 7 G P -82.553 -10.332 66.456 O3' -79.448 -7.980 62.913 8 A P -78.076 -7.195 62.563 O3' -77.328 -2.684 58.950 9 C P -75.780 -2.572 59.336 O3' -73.709 1.907 57.760 1 9 + + c 2 8 - - c 3 7 + + c 4 5 ! ! ! 1 9 3 SG1 4 6 1 439.874 295.289 2 441.527 294.991 3 443.181 294.692 4 445.283 294.475 5 446.607 296.123 6 445.943 298.129 7 443.897 298.661 8 442.243 298.959 9 440.590 299.258 1 3 411 412 413 AAG Crystallography ? ? Angstroms 1 A P -76.379 -39.080 64.039 O3' -78.291 -34.167 66.636 2 A P -78.900 -32.784 67.228 O3' -76.471 -27.422 66.946 3 G P -75.596 -26.499 65.958 O3' -71.717 -28.315 61.471 SG1 1 3 1 426.092 550.000 2 426.092 550.000 3 426.092 550.000 1 9 307 308 309 310 311 312 313 314 315 GUCUAA GAC LOOP1 4 6 LOOP2 4 6 LOOP3 4 6 LOOP4 4 6 LOOP5 4 6 LOOP6 4 6 LOOP7 4 6 LOOP8 4 6 LOOP9 4 6 LOOP10 4 6 LOOP11 4 6 LOOP12 4 6 LOOP13 4 6 LOOP14 4 6 LOOP15 4 6 LOOP16 4 6 LOOP17 4 6 LOOP18 4 6 LOOP19 4 6 LOOP20 4 6 LOOP21 4 6 LOOP22 4 6 LOOP23 4 6 LOOP24 4 6 LOOP25 4 6 LOOP26 4 6 LOOP27 4 6 LOOP28 4 6 LOOP29 4 6 LOOP30 4 6 LOOP31 4 6 LOOP32 4 6 LOOP33 4 6 LOOP34 4 6 LOOP35 4 6 LOOP36 4 6 LOOP37 4 6 LOOP38 4 6 LOOP39 4 6 LOOP40 4 6 LOOP41 4 6 LOOP42 4 6 LOOP43 4 6 LOOP44 4 6 LOOP45 4 6 LOOP46 4 6 LOOP47 4 6 LOOP48 4 6 LOOP49 4 6 LOOP50 4 6 LOOP51 4 6 LOOP52 4 6 LOOP53 4 6 LOOP54 4 6 LOOP55 4 6 LOOP56 4 6 LOOP57 4 6 LOOP58 4 6 LOOP59 4 6 LOOP60 4 6 Crystallography ? ? Angstroms 1 G P -66.613 -21.582 82.106 O3' -67.752 -25.140 78.611 2 U P -67.714 -26.540 79.391 O3' -66.832 -31.041 76.893 3 C P -66.956 -32.203 77.986 O3' -64.094 -36.524 77.780 4 U P -64.244 -37.566 79.000 O3' -58.746 -38.200 80.876 5 A P -58.740 -39.053 82.243 O3' -56.872 -35.412 86.349 6 A P -55.794 -36.163 87.261 O3' -51.405 -32.958 88.762 7 G P -50.234 -33.366 87.757 O3' -49.691 -32.052 82.687 8 A P -49.560 -30.910 81.548 O3' -51.958 -30.824 76.237 9 C P -51.379 -29.362 75.948 O3' -53.624 -27.166 71.829 1 9 + + c 2 8 - - c 3 7 + + c 4 5 ! ! ! 1 9 3 SG1 4 6 1 373.957 348.075 2 375.220 349.183 3 376.484 350.291 4 378.174 351.560 5 380.158 350.831 6 380.622 348.769 7 379.142 347.259 8 377.879 346.151 9 376.616 345.043 1 3 411 412 413 AAG Crystallography ? ? Angstroms 1 A P -22.793 -38.691 97.187 O3' -28.485 -37.305 97.643 2 A P -30.087 -37.044 97.684 O3' -33.222 -33.608 94.067 3 G P -33.285 -33.151 92.523 O3' -28.668 -33.019 88.383 SG1 1 3 1 426.092 550.000 2 426.092 550.000 3 426.092 550.000 1 9 307 308 309 310 311 312 313 314 315 GUCU AAGAC LOOP1 4 6 LOOP2 4 6 LOOP3 4 6 LOOP4 4 6 LOOP5 4 6 LOOP6 4 6 LOOP7 4 6 LOOP8 4 6 LOOP9 4 6 LOOP10 4 6 LOOP11 4 6 LOOP12 4 6 LOOP13 4 6 LOOP14 4 6 LOOP15 4 6 LOOP16 4 6 LOOP17 4 6 LOOP18 4 6 LOOP19 4 6 LOOP20 4 6 LOOP21 4 6 LOOP22 4 6 LOOP23 4 6 LOOP24 4 6 LOOP25 4 6 LOOP26 4 6 LOOP27 4 6 LOOP28 4 6 LOOP29 4 6 LOOP30 4 6 LOOP31 4 6 LOOP32 4 6 LOOP33 4 6 LOOP34 4 6 LOOP35 4 6 LOOP36 4 6 LOOP37 4 6 LOOP38 4 6 LOOP39 4 6 LOOP40 4 6 LOOP41 4 6 LOOP42 4 6 LOOP43 4 6 LOOP44 4 6 LOOP45 4 6 LOOP46 4 6 LOOP47 4 6 LOOP48 4 6 LOOP49 4 6 LOOP50 4 6 LOOP51 4 6 LOOP52 4 6 LOOP53 4 6 LOOP54 4 6 LOOP55 4 6 LOOP56 4 6 LOOP57 4 6 LOOP58 4 6 LOOP59 4 6 LOOP60 4 6 Crystallography ? ? Angstroms 1 G P -37.099 -15.998 100.061 O3' -33.815 -19.848 99.321 2 U P -32.846 -19.841 100.598 O3' -28.034 -21.862 100.393 3 C P -27.424 -21.743 101.868 O3' -22.374 -20.931 102.728 4 U P -21.910 -20.730 104.259 O3' -19.131 -15.591 104.125 5 A P -18.785 -15.128 105.630 O3' -21.934 -10.353 106.566 6 A P -21.016 -9.253 107.275 O3' -21.861 -3.996 105.421 7 G P -20.675 -3.727 104.388 O3' -20.153 -5.568 99.481 8 A P -20.731 -5.710 97.977 O3' -20.602 -10.384 94.496 9 C P -21.443 -9.624 93.368 O3' -23.294 -12.892 89.800 1 9 + + c 2 8 - - c 3 7 + + c 4 5 ! ! ! 1 9 3 SG1 4 6 1 316.360 291.733 2 316.360 293.413 3 316.360 295.093 4 316.519 297.201 5 318.376 298.212 6 320.233 297.201 7 320.392 295.093 8 320.392 293.413 9 320.392 291.733 1 3 411 412 413 AAG Crystallography ? ? Angstroms 1 A P -5.041 21.286 104.801 O3' -9.150 17.459 106.530 2 A P -10.177 16.295 107.007 O3' -13.629 12.974 103.574 3 G P -13.630 12.251 102.134 O3' -10.343 13.756 97.095 SG1 1 3 1 426.092 550.000 2 426.092 550.000 3 426.092 550.000 1 9 307 308 309 310 311 312 313 314 315 GU CUAAGAC LOOP1 4 6 LOOP2 4 6 LOOP3 4 6 LOOP4 4 6 LOOP5 4 6 LOOP6 4 6 LOOP7 4 6 LOOP8 4 6 LOOP9 4 6 LOOP10 4 6 LOOP11 4 6 LOOP12 4 6 LOOP13 4 6 LOOP14 4 6 LOOP15 4 6 LOOP16 4 6 LOOP17 4 6 LOOP18 4 6 LOOP19 4 6 LOOP20 4 6 LOOP21 4 6 LOOP22 4 6 LOOP23 4 6 LOOP24 4 6 LOOP25 4 6 LOOP26 4 6 LOOP27 4 6 LOOP28 4 6 LOOP29 4 6 LOOP30 4 6 LOOP31 4 6 LOOP32 4 6 LOOP33 4 6 LOOP34 4 6 LOOP35 4 6 LOOP36 4 6 LOOP37 4 6 LOOP38 4 6 LOOP39 4 6 LOOP40 4 6 LOOP41 4 6 LOOP42 4 6 LOOP43 4 6 LOOP44 4 6 LOOP45 4 6 LOOP46 4 6 LOOP47 4 6 LOOP48 4 6 LOOP49 4 6 LOOP50 4 6 LOOP51 4 6 LOOP52 4 6 LOOP53 4 6 LOOP54 4 6 LOOP55 4 6 LOOP56 4 6 LOOP57 4 6 LOOP58 4 6 LOOP59 4 6 LOOP60 4 6 Crystallography ? ? Angstroms 1 G P -31.674 18.545 101.475 O3' -26.660 19.554 101.533 2 U P -26.518 20.996 102.218 O3' -22.391 24.064 101.303 3 C P -22.572 25.363 102.222 O3' -20.942 30.060 100.745 4 U P -21.279 31.297 101.722 O3' -24.095 35.019 98.205 5 A P -24.699 36.231 99.080 O3' -30.460 35.719 98.696 6 A P -31.096 37.161 98.424 O3' -35.368 37.147 94.745 7 G P -34.724 37.623 93.364 O3' -31.655 34.872 90.087 8 A P -31.430 33.577 89.144 O3' -26.593 30.389 88.494 9 C P -27.344 29.364 87.521 O3' -24.634 25.004 86.839 1 9 + + c 2 8 - - c 3 7 + + c 4 5 ! ! ! 1 9 3 SG1 4 6 1 348.012 211.803 2 346.624 210.856 3 345.235 209.910 4 343.584 208.590 5 343.795 206.487 6 345.676 205.522 7 347.507 206.578 8 348.895 207.524 9 350.284 208.471 1 3 411 412 413 AAG Crystallography ? ? Angstroms 1 A P -47.655 57.967 76.359 O3' -47.007 54.443 81.015 2 A P -46.686 53.522 82.313 O3' -44.768 47.949 82.331 3 G P -43.793 46.963 81.511 O3' -42.066 47.368 75.568 SG1 1 3 1 426.092 550.000 2 426.092 550.000 3 426.092 550.000 1 9 307 308 309 310 311 312 313 314 315 GUCUAAGAC LOOP1 4 6 LOOP2 4 6 LOOP3 4 6 LOOP4 4 6 LOOP5 4 6 LOOP6 4 6 LOOP7 4 6 LOOP8 4 6 LOOP9 4 6 LOOP10 4 6 LOOP11 4 6 LOOP12 4 6 LOOP13 4 6 LOOP14 4 6 LOOP15 4 6 LOOP16 4 6 LOOP17 4 6 LOOP18 4 6 LOOP19 4 6 LOOP20 4 6 LOOP21 4 6 LOOP22 4 6 LOOP23 4 6 LOOP24 4 6 LOOP25 4 6 LOOP26 4 6 LOOP27 4 6 LOOP28 4 6 LOOP29 4 6 LOOP30 4 6 LOOP31 4 6 LOOP32 4 6 LOOP33 4 6 LOOP34 4 6 LOOP35 4 6 LOOP36 4 6 LOOP37 4 6 LOOP38 4 6 LOOP39 4 6 LOOP40 4 6 LOOP41 4 6 LOOP42 4 6 LOOP43 4 6 LOOP44 4 6 LOOP45 4 6 LOOP46 4 6 LOOP47 4 6 LOOP48 4 6 LOOP49 4 6 LOOP50 4 6 LOOP51 4 6 LOOP52 4 6 LOOP53 4 6 LOOP54 4 6 LOOP55 4 6 LOOP56 4 6 LOOP57 4 6 LOOP58 4 6 LOOP59 4 6 LOOP60 4 6 Crystallography ? ? Angstroms 1 G P -102.357 32.344 11.016 O3' -102.471 27.395 12.300 2 U P -103.236 27.330 13.708 O3' -102.494 23.385 17.050 3 C P -103.485 23.636 18.281 O3' -102.274 22.278 23.138 4 U P -103.319 22.680 24.298 O3' -100.017 25.711 28.047 5 A P -100.958 26.380 29.172 O3' -100.546 32.104 28.360 6 A P -100.357 32.820 29.776 O3' -96.682 37.097 29.729 7 G P -95.330 36.485 30.317 O3' -91.903 33.276 27.932 8 A P -90.889 32.982 26.705 O3' -90.061 27.976 23.836 9 C P -89.033 28.672 22.827 O3' -88.106 25.724 18.670 1 9 + + c 2 8 - - c 3 7 + + c 4 5 ! ! ! 1 9 3 SG1 4 6 1 502.437 233.940 2 503.920 234.731 3 505.402 235.521 4 507.337 236.372 5 509.103 235.209 6 509.085 233.096 7 507.300 231.963 8 505.817 231.172 9 504.335 230.382 1 3 411 412 413 A AG Crystallography ? ? Angstroms 1 A P -79.494 50.590 50.824 O3' -83.946 49.730 47.086 2 A P -85.190 49.354 46.114 O3' -84.894 47.127 40.666 3 G P -84.020 46.101 39.784 O3' -78.109 44.418 40.618 SG1 1 3 1 426.092 550.000 2 426.092 550.000 3 426.092 550.000 1 9 307 308 309 310 311 312 313 314 315 GUCUAAGA C LOOP1 4 6 LOOP2 4 6 LOOP3 4 6 LOOP4 4 6 LOOP5 4 6 LOOP6 4 6 LOOP7 4 6 LOOP8 4 6 LOOP9 4 6 LOOP10 4 6 LOOP11 4 6 LOOP12 4 6 LOOP13 4 6 LOOP14 4 6 LOOP15 4 6 LOOP16 4 6 LOOP17 4 6 LOOP18 4 6 LOOP19 4 6 LOOP20 4 6 LOOP21 4 6 LOOP22 4 6 LOOP23 4 6 LOOP24 4 6 LOOP25 4 6 LOOP26 4 6 LOOP27 4 6 LOOP28 4 6 LOOP29 4 6 LOOP30 4 6 LOOP31 4 6 LOOP32 4 6 LOOP33 4 6 LOOP34 4 6 LOOP35 4 6 LOOP36 4 6 LOOP37 4 6 LOOP38 4 6 LOOP39 4 6 LOOP40 4 6 LOOP41 4 6 LOOP42 4 6 LOOP43 4 6 LOOP44 4 6 LOOP45 4 6 LOOP46 4 6 LOOP47 4 6 LOOP48 4 6 LOOP49 4 6 LOOP50 4 6 LOOP51 4 6 LOOP52 4 6 LOOP53 4 6 LOOP54 4 6 LOOP55 4 6 LOOP56 4 6 LOOP57 4 6 LOOP58 4 6 LOOP59 4 6 LOOP60 4 6 Crystallography ? ? Angstroms 1 G P -86.189 59.402 26.218 O3' -84.229 57.994 30.728 2 U P -84.103 59.343 31.585 O3' -80.671 59.790 35.497 3 C P -80.906 61.232 36.150 O3' -77.037 64.024 38.184 4 U P -77.396 65.502 38.716 O3' -73.638 68.898 35.802 5 A P -74.006 70.446 36.055 O3' -75.697 72.518 30.913 6 A P -75.013 73.943 30.673 O3' -73.264 74.804 25.381 7 G P -71.695 74.512 25.413 O3' -69.255 69.853 25.654 8 A P -68.985 68.385 25.028 O3' -68.394 63.316 27.843 9 C P -68.278 62.511 26.466 O3' -68.849 57.409 27.148 1 9 + + c 2 8 - - c 3 7 + + c 4 5 ! ! ! 1 9 3 SG1 4 6 1 478.186 146.422 2 479.862 146.299 3 481.538 146.177 4 483.651 146.183 5 484.794 147.961 6 483.922 149.886 7 481.831 150.199 8 480.155 150.321 9 478.479 150.444 1 3 411 412 413 AAG Crystallography ? ? Angstroms 1 A P -52.246 92.597 12.570 O3' -57.536 90.683 14.263 2 A P -58.940 90.137 14.870 O3' -60.891 84.576 14.866 3 G P -60.351 83.065 15.013 O3' -54.666 80.900 13.802 SG1 1 3 1 426.092 550.000 2 426.092 550.000 3 426.092 550.000 1 9 307 308 309 310 311 312 313 314 315 GUCUAA GAC LOOP1 4 6 LOOP2 4 6 LOOP3 4 6 LOOP4 4 6 LOOP5 4 6 LOOP6 4 6 LOOP7 4 6 LOOP8 4 6 LOOP9 4 6 LOOP10 4 6 LOOP11 4 6 LOOP12 4 6 LOOP13 4 6 LOOP14 4 6 LOOP15 4 6 LOOP16 4 6 LOOP17 4 6 LOOP18 4 6 LOOP19 4 6 LOOP20 4 6 LOOP21 4 6 LOOP22 4 6 LOOP23 4 6 LOOP24 4 6 LOOP25 4 6 LOOP26 4 6 LOOP27 4 6 LOOP28 4 6 LOOP29 4 6 LOOP30 4 6 LOOP31 4 6 LOOP32 4 6 LOOP33 4 6 LOOP34 4 6 LOOP35 4 6 LOOP36 4 6 LOOP37 4 6 LOOP38 4 6 LOOP39 4 6 LOOP40 4 6 LOOP41 4 6 LOOP42 4 6 LOOP43 4 6 LOOP44 4 6 LOOP45 4 6 LOOP46 4 6 LOOP47 4 6 LOOP48 4 6 LOOP49 4 6 LOOP50 4 6 LOOP51 4 6 LOOP52 4 6 LOOP53 4 6 LOOP54 4 6 LOOP55 4 6 LOOP56 4 6 LOOP57 4 6 LOOP58 4 6 LOOP59 4 6 LOOP60 4 6 Crystallography ? ? Angstroms 1 G P -72.843 79.608 0.955 O3' -68.534 81.845 2.561 2 U P -68.367 83.161 1.659 O3' -63.695 85.352 0.849 3 C P -63.953 86.672 -0.016 O3' -60.554 88.387 -3.540 4 U P -60.984 89.672 -4.414 O3' -60.402 87.776 -9.910 5 A P -61.003 88.876 -10.924 O3' -65.609 86.374 -13.399 6 A P -65.578 86.663 -14.971 O3' -67.138 82.280 -18.158 7 G P -65.771 81.633 -18.665 O3' -62.365 78.676 -15.946 8 A P -62.060 77.353 -15.068 O3' -58.705 76.869 -10.325 9 C P -59.098 75.329 -10.148 O3' -57.776 73.518 -5.480 1 9 + + c 2 8 - - c 3 7 + + c 4 5 ! ! ! 1 9 3 SG1 4 6 1 462.966 108.545 2 463.889 107.141 3 464.811 105.736 4 466.102 104.062 5 468.208 104.237 6 469.205 106.101 7 468.181 107.950 8 467.259 109.355 9 466.337 110.759 1 3 411 412 413 AAG Crystallography ? ? Angstroms 1 A P -61.742 73.864 -46.838 O3' -64.611 76.040 -42.194 2 A P -65.280 76.725 -40.884 O3' -65.301 74.601 -35.386 3 G P -64.365 73.782 -34.362 O3' -59.784 69.821 -35.702 SG1 1 3 1 426.092 550.000 2 426.092 550.000 3 426.092 550.000 1 9 307 308 309 310 311 312 313 314 315 GUCU AAGAC LOOP1 4 6 LOOP2 4 6 LOOP3 4 6 LOOP4 4 6 LOOP5 4 6 LOOP6 4 6 LOOP7 4 6 LOOP8 4 6 LOOP9 4 6 LOOP10 4 6 LOOP11 4 6 LOOP12 4 6 LOOP13 4 6 LOOP14 4 6 LOOP15 4 6 LOOP16 4 6 LOOP17 4 6 LOOP18 4 6 LOOP19 4 6 LOOP20 4 6 LOOP21 4 6 LOOP22 4 6 LOOP23 4 6 LOOP24 4 6 LOOP25 4 6 LOOP26 4 6 LOOP27 4 6 LOOP28 4 6 LOOP29 4 6 LOOP30 4 6 LOOP31 4 6 LOOP32 4 6 LOOP33 4 6 LOOP34 4 6 LOOP35 4 6 LOOP36 4 6 LOOP37 4 6 LOOP38 4 6 LOOP39 4 6 LOOP40 4 6 LOOP41 4 6 LOOP42 4 6 LOOP43 4 6 LOOP44 4 6 LOOP45 4 6 LOOP46 4 6 LOOP47 4 6 LOOP48 4 6 LOOP49 4 6 LOOP50 4 6 LOOP51 4 6 LOOP52 4 6 LOOP53 4 6 LOOP54 4 6 LOOP55 4 6 LOOP56 4 6 LOOP57 4 6 LOOP58 4 6 LOOP59 4 6 LOOP60 4 6 Crystallography ? ? Angstroms 1 G P -80.764 65.038 -29.862 O3' -77.075 65.987 -33.275 2 U P -77.775 65.869 -34.712 O3' -75.028 64.743 -39.010 3 C P -76.054 64.798 -40.237 O3' -75.606 61.698 -44.371 4 U P -76.765 61.786 -45.487 O3' -78.602 56.256 -45.915 5 A P -79.920 56.198 -46.842 O3' -84.223 54.524 -43.338 6 A P -85.092 53.403 -44.077 O3' -86.771 49.195 -40.720 7 G P -85.745 48.007 -41.004 O3' -80.756 47.554 -39.380 8 A P -79.684 47.492 -38.170 O3' -74.385 49.906 -37.921 9 C P -74.179 49.412 -36.416 O3' -70.189 51.789 -34.122 1 9 + + c 2 8 - - c 3 7 + + c 4 5 ! ! ! 1 9 3 SG1 4 6 1 478.895 168.316 2 479.876 166.952 3 480.858 165.588 4 482.218 163.970 5 484.316 164.234 6 485.233 166.138 7 484.131 167.943 8 483.150 169.307 9 482.169 170.671 1 3 411 412 413 AAG Crystallography ? ? Angstroms 1 A P -94.860 20.280 -45.300 O3' -95.393 26.039 -44.264 2 A P -95.449 27.654 -44.096 O3' -92.030 30.988 -40.644 3 G P -90.514 31.081 -40.106 O3' -86.389 26.492 -39.481 SG1 1 3 1 426.092 550.000 2 426.092 550.000 3 426.092 550.000 1 9 307 308 309 310 311 312 313 314 315 GU CUAAGAC LOOP1 4 6 LOOP2 4 6 LOOP3 4 6 LOOP4 4 6 LOOP5 4 6 LOOP6 4 6 LOOP7 4 6 LOOP8 4 6 LOOP9 4 6 LOOP10 4 6 LOOP11 4 6 LOOP12 4 6 LOOP13 4 6 LOOP14 4 6 LOOP15 4 6 LOOP16 4 6 LOOP17 4 6 LOOP18 4 6 LOOP19 4 6 LOOP20 4 6 LOOP21 4 6 LOOP22 4 6 LOOP23 4 6 LOOP24 4 6 LOOP25 4 6 LOOP26 4 6 LOOP27 4 6 LOOP28 4 6 LOOP29 4 6 LOOP30 4 6 LOOP31 4 6 LOOP32 4 6 LOOP33 4 6 LOOP34 4 6 LOOP35 4 6 LOOP36 4 6 LOOP37 4 6 LOOP38 4 6 LOOP39 4 6 LOOP40 4 6 LOOP41 4 6 LOOP42 4 6 LOOP43 4 6 LOOP44 4 6 LOOP45 4 6 LOOP46 4 6 LOOP47 4 6 LOOP48 4 6 LOOP49 4 6 LOOP50 4 6 LOOP51 4 6 LOOP52 4 6 LOOP53 4 6 LOOP54 4 6 LOOP55 4 6 LOOP56 4 6 LOOP57 4 6 LOOP58 4 6 LOOP59 4 6 LOOP60 4 6 Crystallography ? ? Angstroms 1 G P -99.004 35.828 -23.644 O3' -98.049 32.335 -27.255 2 U P -99.325 31.364 -27.266 O3' -99.007 26.446 -28.999 3 C P -100.486 25.839 -28.929 O3' -101.390 20.840 -27.884 4 U P -102.929 20.384 -27.743 O3' -103.085 17.898 -22.456 5 A P -104.614 17.573 -22.061 O3' -105.816 20.983 -17.529 6 A P -106.586 20.126 -16.421 O3' -105.030 21.270 -11.123 7 G P -104.013 20.103 -10.732 O3' -99.012 19.495 -12.261 8 A P -97.501 20.069 -12.352 O3' -93.764 19.689 -16.808 9 C P -92.680 20.575 -16.036 O3' -88.934 22.250 -19.197 1 9 + + c 2 8 - - c 3 7 + + c 4 5 ! ! ! 1 9 3 SG1 4 6 1 504.297 243.046 2 505.971 243.191 3 507.645 243.337 4 509.731 243.678 5 510.578 245.615 6 509.411 247.377 7 507.297 247.354 8 505.623 247.209 9 503.949 247.064 1 3 411 412 413 AAG Crystallography ? ? Angstroms 1 A P -105.832 5.896 15.059 O3' -107.343 9.779 10.916 2 A P -107.754 10.738 9.671 O3' -104.140 14.008 6.359 3 G P -102.662 13.973 5.718 O3' -97.715 10.792 7.687 SG1 1 3 1 426.092 550.000 2 426.092 550.000 3 426.092 550.000 1 9 307 308 309 310 311 312 313 314 315 GUCUAAGAC LOOP1 4 6 LOOP2 4 6 LOOP3 4 6 LOOP4 4 6 LOOP5 4 6 LOOP6 4 6 LOOP7 4 6 LOOP8 4 6 LOOP9 4 6 LOOP10 4 6 LOOP11 4 6 LOOP12 4 6 LOOP13 4 6 LOOP14 4 6 LOOP15 4 6 LOOP16 4 6 LOOP17 4 6 LOOP18 4 6 LOOP19 4 6 LOOP20 4 6 LOOP21 4 6 LOOP22 4 6 LOOP23 4 6 LOOP24 4 6 LOOP25 4 6 LOOP26 4 6 LOOP27 4 6 LOOP28 4 6 LOOP29 4 6 LOOP30 4 6 LOOP31 4 6 LOOP32 4 6 LOOP33 4 6 LOOP34 4 6 LOOP35 4 6 LOOP36 4 6 LOOP37 4 6 LOOP38 4 6 LOOP39 4 6 LOOP40 4 6 LOOP41 4 6 LOOP42 4 6 LOOP43 4 6 LOOP44 4 6 LOOP45 4 6 LOOP46 4 6 LOOP47 4 6 LOOP48 4 6 LOOP49 4 6 LOOP50 4 6 LOOP51 4 6 LOOP52 4 6 LOOP53 4 6 LOOP54 4 6 LOOP55 4 6 LOOP56 4 6 LOOP57 4 6 LOOP58 4 6 LOOP59 4 6 LOOP60 4 6 Crystallography ? ? Angstroms 1 G P 80.764 -67.978 -22.378 O3' 77.075 -69.303 -25.663 2 U P 77.775 -69.346 -27.105 O3' 75.028 -68.710 -31.502 3 C P 76.054 -68.902 -32.714 O3' 75.606 -66.286 -37.170 4 U P 76.765 -66.499 -38.270 O3' 78.602 -61.051 -39.315 5 A P 79.920 -61.098 -40.242 O3' 84.223 -59.041 -36.949 6 A P 85.092 -58.010 -37.808 O3' 86.771 -53.452 -34.944 7 G P 85.745 -52.303 -35.361 O3' 80.756 -51.671 -33.797 8 A P 79.684 -51.473 -32.601 O3' 74.385 -53.845 -32.084 9 C P 74.179 -53.185 -30.643 O3' 70.189 -55.290 -28.097 1 9 + + c 2 8 - - c 3 7 + + c 4 5 ! ! ! 1 9 3 SG1 4 6 1 27.366 337.345 2 26.410 338.727 3 25.455 340.109 4 24.388 341.934 5 25.341 343.821 6 27.443 344.045 7 28.773 342.402 8 29.728 341.020 9 30.683 339.637 1 3 411 412 413 A AG Crystallography ? ? Angstroms 1 A P 94.860 -25.234 -42.739 O3' 95.393 -30.840 -41.063 2 A P 95.449 -32.425 -40.716 O3' 92.030 -35.352 -36.912 3 G P 90.514 -35.385 -36.367 O3' 86.389 -30.754 -36.261 SG1 1 3 1 426.092 550.000 2 426.092 550.000 3 426.092 550.000 1 9 307 308 309 310 311 312 313 314 315 GUCUAAGA C LOOP1 4 6 LOOP2 4 6 LOOP3 4 6 LOOP4 4 6 LOOP5 4 6 LOOP6 4 6 LOOP7 4 6 LOOP8 4 6 LOOP9 4 6 LOOP10 4 6 LOOP11 4 6 LOOP12 4 6 LOOP13 4 6 LOOP14 4 6 LOOP15 4 6 LOOP16 4 6 LOOP17 4 6 LOOP18 4 6 LOOP19 4 6 LOOP20 4 6 LOOP21 4 6 LOOP22 4 6 LOOP23 4 6 LOOP24 4 6 LOOP25 4 6 LOOP26 4 6 LOOP27 4 6 LOOP28 4 6 LOOP29 4 6 LOOP30 4 6 LOOP31 4 6 LOOP32 4 6 LOOP33 4 6 LOOP34 4 6 LOOP35 4 6 LOOP36 4 6 LOOP37 4 6 LOOP38 4 6 LOOP39 4 6 LOOP40 4 6 LOOP41 4 6 LOOP42 4 6 LOOP43 4 6 LOOP44 4 6 LOOP45 4 6 LOOP46 4 6 LOOP47 4 6 LOOP48 4 6 LOOP49 4 6 LOOP50 4 6 LOOP51 4 6 LOOP52 4 6 LOOP53 4 6 LOOP54 4 6 LOOP55 4 6 LOOP56 4 6 LOOP57 4 6 LOOP58 4 6 LOOP59 4 6 LOOP60 4 6 Crystallography ? ? Angstroms 1 G P 99.004 -38.254 -19.475 O3' 98.049 -35.188 -23.456 2 U P 99.325 -34.224 -23.576 O3' 99.007 -29.532 -25.849 3 C P 100.486 -28.921 -25.847 O3' 101.390 -23.837 -25.370 4 U P 102.929 -23.367 -25.281 O3' 103.085 -20.304 -20.308 5 A P 104.614 -19.938 -19.951 O3' 105.816 -22.817 -15.065 6 A P 106.586 -21.841 -14.060 O3' 105.030 -22.384 -8.667 7 G P 104.013 -21.181 -8.409 O3' 99.012 -20.748 -9.997 8 A P 97.501 -21.328 -10.024 O3' 93.764 -21.451 -14.494 9 C P 92.680 -22.244 -13.626 O3' 88.934 -24.263 -16.579 1 9 + + c 2 8 - - c 3 7 + + c 4 5 ! ! ! 1 9 3 SG1 4 6 1 6.457 256.975 2 4.777 256.993 3 3.097 257.011 4 0.991 257.192 5 0.000 259.059 6 1.030 260.905 7 3.139 261.043 8 4.819 261.025 9 6.500 261.008 1 3 411 412 413 AAG Crystallography ? ? Angstroms 1 A P 105.832 -4.170 15.625 O3' 107.343 -8.493 11.944 2 A P 107.754 -9.585 10.814 O3' 104.140 -13.206 7.890 3 G P 102.662 -13.244 7.249 O3' 97.715 -9.862 8.848 SG1 1 3 1 426.092 550.000 2 426.092 550.000 3 426.092 550.000 1 9 307 308 309 310 311 312 313 314 315 GUCUAA GAC LOOP1 4 6 LOOP2 4 6 LOOP3 4 6 LOOP4 4 6 LOOP5 4 6 LOOP6 4 6 LOOP7 4 6 LOOP8 4 6 LOOP9 4 6 LOOP10 4 6 LOOP11 4 6 LOOP12 4 6 LOOP13 4 6 LOOP14 4 6 LOOP15 4 6 LOOP16 4 6 LOOP17 4 6 LOOP18 4 6 LOOP19 4 6 LOOP20 4 6 LOOP21 4 6 LOOP22 4 6 LOOP23 4 6 LOOP24 4 6 LOOP25 4 6 LOOP26 4 6 LOOP27 4 6 LOOP28 4 6 LOOP29 4 6 LOOP30 4 6 LOOP31 4 6 LOOP32 4 6 LOOP33 4 6 LOOP34 4 6 LOOP35 4 6 LOOP36 4 6 LOOP37 4 6 LOOP38 4 6 LOOP39 4 6 LOOP40 4 6 LOOP41 4 6 LOOP42 4 6 LOOP43 4 6 LOOP44 4 6 LOOP45 4 6 LOOP46 4 6 LOOP47 4 6 LOOP48 4 6 LOOP49 4 6 LOOP50 4 6 LOOP51 4 6 LOOP52 4 6 LOOP53 4 6 LOOP54 4 6 LOOP55 4 6 LOOP56 4 6 LOOP57 4 6 LOOP58 4 6 LOOP59 4 6 LOOP60 4 6 Crystallography ? ? Angstroms 1 G P 102.357 -30.904 14.575 O3' 102.471 -25.842 15.296 2 U P 103.236 -25.621 16.687 O3' 102.494 -21.325 19.565 3 C P 103.485 -21.436 20.817 O3' 102.274 -19.541 25.491 4 U P 103.319 -19.812 26.689 O3' 100.017 -22.403 30.754 5 A P 100.958 -22.941 31.948 O3' 100.546 -28.720 31.782 6 A P 100.357 -29.272 33.270 O3' 96.682 -33.528 33.703 7 G P 95.330 -32.854 34.218 O3' 91.903 -29.933 31.488 8 A P 90.889 -29.779 30.237 O3' 90.061 -25.126 26.824 9 C P 89.033 -25.930 25.899 O3' 88.106 -23.468 21.438 1 9 + + c 2 8 - - c 3 7 + + c 4 5 ! ! ! 1 9 3 SG1 4 6 1 8.852 264.136 2 7.371 263.341 3 5.891 262.547 4 4.109 261.409 5 4.097 259.295 6 5.865 258.137 7 7.798 258.994 8 9.278 259.788 9 10.759 260.583 1 3 411 412 413 AAG Crystallography ? ? Angstroms 1 A P 79.494 -44.570 56.178 O3' 83.946 -44.135 52.367 2 A P 85.190 -43.870 51.359 O3' 84.894 -42.268 45.695 3 G P 84.020 -41.347 44.704 O3' 78.109 -39.581 45.344 SG1 1 3 1 426.092 550.000 2 426.092 550.000 3 426.092 550.000 1 9 307 308 309 310 311 312 313 314 315 GUCU AAGAC LOOP1 4 6 LOOP2 4 6 LOOP3 4 6 LOOP4 4 6 LOOP5 4 6 LOOP6 4 6 LOOP7 4 6 LOOP8 4 6 LOOP9 4 6 LOOP10 4 6 LOOP11 4 6 LOOP12 4 6 LOOP13 4 6 LOOP14 4 6 LOOP15 4 6 LOOP16 4 6 LOOP17 4 6 LOOP18 4 6 LOOP19 4 6 LOOP20 4 6 LOOP21 4 6 LOOP22 4 6 LOOP23 4 6 LOOP24 4 6 LOOP25 4 6 LOOP26 4 6 LOOP27 4 6 LOOP28 4 6 LOOP29 4 6 LOOP30 4 6 LOOP31 4 6 LOOP32 4 6 LOOP33 4 6 LOOP34 4 6 LOOP35 4 6 LOOP36 4 6 LOOP37 4 6 LOOP38 4 6 LOOP39 4 6 LOOP40 4 6 LOOP41 4 6 LOOP42 4 6 LOOP43 4 6 LOOP44 4 6 LOOP45 4 6 LOOP46 4 6 LOOP47 4 6 LOOP48 4 6 LOOP49 4 6 LOOP50 4 6 LOOP51 4 6 LOOP52 4 6 LOOP53 4 6 LOOP54 4 6 LOOP55 4 6 LOOP56 4 6 LOOP57 4 6 LOOP58 4 6 LOOP59 4 6 LOOP60 4 6 Crystallography ? ? Angstroms 1 G P 86.189 -56.086 32.716 O3' 84.229 -54.180 37.039 2 U P 84.103 -55.426 38.041 O3' 80.671 -55.431 41.979 3 C P 80.906 -56.791 42.790 O3' 77.037 -59.337 45.124 4 U P 77.396 -60.746 45.819 O3' 73.638 -64.447 43.303 5 A P 74.006 -65.957 43.730 O3' 75.697 -68.593 38.852 6 A P 75.013 -70.036 38.774 O3' 73.264 -71.485 33.613 7 G P 71.695 -71.191 33.612 O3' 69.255 -66.534 33.328 8 A P 68.985 -65.146 32.541 O3' 68.394 -59.793 34.769 9 C P 68.278 -59.149 33.311 O3' 68.849 -54.001 33.417 1 9 + + c 2 8 - - c 3 7 + + c 4 5 ! ! ! 1 9 3 SG1 4 6 1 35.508 342.037 2 33.828 341.992 3 32.148 341.947 4 30.037 342.050 5 28.977 343.878 6 29.937 345.762 7 32.040 345.978 8 33.719 346.023 9 35.399 346.068 1 3 411 412 413 AAG Crystallography ? ? Angstroms 1 A P 52.246 -90.603 22.878 O3' 57.536 -88.510 24.345 2 A P 58.940 -87.900 24.887 O3' 60.891 -82.375 24.260 3 G P 60.351 -80.856 24.236 O3' 54.666 -78.841 22.790 SG1 1 3 1 426.092 550.000 2 426.092 550.000 3 426.092 550.000 1 9 307 308 309 310 311 312 313 314 315 GU CUAAGAC LOOP1 4 6 LOOP2 4 6 LOOP3 4 6 LOOP4 4 6 LOOP5 4 6 LOOP6 4 6 LOOP7 4 6 LOOP8 4 6 LOOP9 4 6 LOOP10 4 6 LOOP11 4 6 LOOP12 4 6 LOOP13 4 6 LOOP14 4 6 LOOP15 4 6 LOOP16 4 6 LOOP17 4 6 LOOP18 4 6 LOOP19 4 6 LOOP20 4 6 LOOP21 4 6 LOOP22 4 6 LOOP23 4 6 LOOP24 4 6 LOOP25 4 6 LOOP26 4 6 LOOP27 4 6 LOOP28 4 6 LOOP29 4 6 LOOP30 4 6 LOOP31 4 6 LOOP32 4 6 LOOP33 4 6 LOOP34 4 6 LOOP35 4 6 LOOP36 4 6 LOOP37 4 6 LOOP38 4 6 LOOP39 4 6 LOOP40 4 6 LOOP41 4 6 LOOP42 4 6 LOOP43 4 6 LOOP44 4 6 LOOP45 4 6 LOOP46 4 6 LOOP47 4 6 LOOP48 4 6 LOOP49 4 6 LOOP50 4 6 LOOP51 4 6 LOOP52 4 6 LOOP53 4 6 LOOP54 4 6 LOOP55 4 6 LOOP56 4 6 LOOP57 4 6 LOOP58 4 6 LOOP59 4 6 LOOP60 4 6 Crystallography ? ? Angstroms 1 G P 72.843 -78.998 9.879 O3' 68.534 -81.042 11.725 2 U P 68.367 -82.449 10.977 O3' 63.695 -84.718 10.419 3 C P 63.953 -86.127 9.706 O3' 60.554 -88.227 6.398 4 U P 60.984 -89.601 5.673 O3' 60.402 -88.333 -0.002 5 A P 61.003 -89.540 -0.885 O3' 65.609 -87.332 -3.626 6 A P 65.578 -87.796 -5.155 O3' 67.138 -83.799 -8.814 7 G P 65.771 -83.212 -9.390 O3' 62.365 -79.968 -7.021 8 A P 62.060 -78.554 -6.296 O3' 58.705 -77.543 -1.639 9 C P 59.098 -75.992 -1.634 O3' 57.776 -73.669 2.802 1 9 + + c 2 8 - - c 3 7 + + c 4 5 ! ! ! 1 9 3 SG1 4 6 1 45.253 389.885 2 44.309 391.274 3 43.364 392.664 4 42.312 394.497 5 43.280 396.377 6 45.383 396.584 7 46.700 394.930 8 47.644 393.541 9 48.588 392.151 1 3 411 412 413 AAG Crystallography ? ? Angstroms 1 A P 61.742 -78.652 -38.257 O3' 64.611 -80.294 -33.399 2 A P 65.280 -80.826 -32.019 O3' 65.301 -78.100 -26.795 3 G P 64.365 -77.171 -25.869 O3' 59.784 -73.385 -27.645 SG1 1 3 1 426.092 550.000 2 426.092 550.000 3 426.092 550.000 1 9 307 308 309 310 311 312 313 314 315 GUCUAAGAC LOOP1 4 6 LOOP2 4 6 LOOP3 4 6 LOOP4 4 6 LOOP5 4 6 LOOP6 4 6 LOOP7 4 6 LOOP8 4 6 LOOP9 4 6 LOOP10 4 6 LOOP11 4 6 LOOP12 4 6 LOOP13 4 6 LOOP14 4 6 LOOP15 4 6 LOOP16 4 6 LOOP17 4 6 LOOP18 4 6 LOOP19 4 6 LOOP20 4 6 LOOP21 4 6 LOOP22 4 6 LOOP23 4 6 LOOP24 4 6 LOOP25 4 6 LOOP26 4 6 LOOP27 4 6 LOOP28 4 6 LOOP29 4 6 LOOP30 4 6 LOOP31 4 6 LOOP32 4 6 LOOP33 4 6 LOOP34 4 6 LOOP35 4 6 LOOP36 4 6 LOOP37 4 6 LOOP38 4 6 LOOP39 4 6 LOOP40 4 6 LOOP41 4 6 LOOP42 4 6 LOOP43 4 6 LOOP44 4 6 LOOP45 4 6 LOOP46 4 6 LOOP47 4 6 LOOP48 4 6 LOOP49 4 6 LOOP50 4 6 LOOP51 4 6 LOOP52 4 6 LOOP53 4 6 LOOP54 4 6 LOOP55 4 6 LOOP56 4 6 LOOP57 4 6 LOOP58 4 6 LOOP59 4 6 LOOP60 4 6 Crystallography ? ? Angstroms 1 G P 79.428 1.325 -73.033 O3' 81.572 3.293 -68.827 2 U P 82.936 2.478 -68.615 O3' 85.169 2.056 -63.912 3 C P 86.536 1.252 -64.124 O3' 88.447 -1.973 -60.539 4 U P 89.778 -2.797 -60.924 O3' 88.194 -8.349 -60.028 5 A P 89.349 -9.332 -60.574 O3' 86.990 -12.198 -65.026 6 A P 87.368 -13.748 -64.909 O3' 83.171 -17.258 -66.274 7 G P 82.553 -17.722 -64.878 O3' 79.448 -14.987 -61.621 8 A P 78.076 -14.168 -61.361 O3' 77.328 -9.279 -58.276 9 C P 75.780 -9.211 -58.673 O3' 73.709 -4.584 -57.609 1 9 + + c 2 8 - - c 3 7 + + c 4 5 ! ! ! 1 9 3 SG1 4 6 1 66.515 218.289 2 65.198 217.245 3 63.882 216.201 4 62.330 214.766 5 62.692 212.684 6 64.637 211.857 7 66.388 213.042 8 67.704 214.086 9 69.021 215.130 1 3 411 412 413 A AG Crystallography ? ? Angstroms 1 A P 76.379 -46.015 -59.251 O3' 78.291 -41.426 -62.383 2 A P 78.900 -40.118 -63.126 O3' 76.471 -34.758 -63.448 3 G P 75.596 -33.731 -62.569 O3' 71.717 -35.031 -57.907 SG1 1 3 1 426.092 550.000 2 426.092 550.000 3 426.092 550.000 1 9 307 308 309 310 311 312 313 314 315 GUCUAAGA C LOOP1 4 6 LOOP2 4 6 LOOP3 4 6 LOOP4 4 6 LOOP5 4 6 LOOP6 4 6 LOOP7 4 6 LOOP8 4 6 LOOP9 4 6 LOOP10 4 6 LOOP11 4 6 LOOP12 4 6 LOOP13 4 6 LOOP14 4 6 LOOP15 4 6 LOOP16 4 6 LOOP17 4 6 LOOP18 4 6 LOOP19 4 6 LOOP20 4 6 LOOP21 4 6 LOOP22 4 6 LOOP23 4 6 LOOP24 4 6 LOOP25 4 6 LOOP26 4 6 LOOP27 4 6 LOOP28 4 6 LOOP29 4 6 LOOP30 4 6 LOOP31 4 6 LOOP32 4 6 LOOP33 4 6 LOOP34 4 6 LOOP35 4 6 LOOP36 4 6 LOOP37 4 6 LOOP38 4 6 LOOP39 4 6 LOOP40 4 6 LOOP41 4 6 LOOP42 4 6 LOOP43 4 6 LOOP44 4 6 LOOP45 4 6 LOOP46 4 6 LOOP47 4 6 LOOP48 4 6 LOOP49 4 6 LOOP50 4 6 LOOP51 4 6 LOOP52 4 6 LOOP53 4 6 LOOP54 4 6 LOOP55 4 6 LOOP56 4 6 LOOP57 4 6 LOOP58 4 6 LOOP59 4 6 LOOP60 4 6 Crystallography ? ? Angstroms 1 G P 66.613 -30.657 -79.166 O3' 67.752 -33.799 -75.295 2 U P 67.714 -35.277 -75.913 O3' 66.832 -39.470 -72.926 3 C P 66.956 -40.748 -73.881 O3' 64.094 -45.018 -73.193 4 U P 64.244 -46.191 -74.288 O3' 58.746 -47.031 -76.080 5 A P 58.740 -48.031 -77.344 O3' 56.872 -44.875 -81.831 6 A P 55.794 -45.723 -82.654 O3' 51.405 -42.706 -84.505 7 G P 50.234 -42.999 -83.461 O3' 49.691 -41.125 -78.570 8 A P 49.560 -39.861 -77.567 O3' 51.958 -39.182 -72.298 9 C P 51.379 -37.696 -72.175 O3' 53.624 -35.053 -68.328 1 9 + + c 2 8 - - c 3 7 + + c 4 5 ! ! ! 1 9 3 SG1 4 6 1 97.966 293.242 2 96.330 293.623 3 94.693 294.004 4 92.676 294.638 5 92.114 296.676 6 93.519 298.255 7 95.608 297.932 8 97.244 297.551 9 98.881 297.169 1 3 411 412 413 AAG Crystallography ? ? Angstroms 1 A P 22.793 -49.348 -92.234 O3' 28.485 -48.023 -92.842 2 A P 30.087 -47.768 -92.912 O3' 33.222 -43.948 -89.703 3 G P 33.285 -43.321 -88.220 O3' 28.668 -42.724 -84.122 SG1 1 3 1 426.092 550.000 2 426.092 550.000 3 426.092 550.000 1 9 307 308 309 310 311 312 313 314 315 GUCUAA GAC LOOP1 4 6 LOOP2 4 6 LOOP3 4 6 LOOP4 4 6 LOOP5 4 6 LOOP6 4 6 LOOP7 4 6 LOOP8 4 6 LOOP9 4 6 LOOP10 4 6 LOOP11 4 6 LOOP12 4 6 LOOP13 4 6 LOOP14 4 6 LOOP15 4 6 LOOP16 4 6 LOOP17 4 6 LOOP18 4 6 LOOP19 4 6 LOOP20 4 6 LOOP21 4 6 LOOP22 4 6 LOOP23 4 6 LOOP24 4 6 LOOP25 4 6 LOOP26 4 6 LOOP27 4 6 LOOP28 4 6 LOOP29 4 6 LOOP30 4 6 LOOP31 4 6 LOOP32 4 6 LOOP33 4 6 LOOP34 4 6 LOOP35 4 6 LOOP36 4 6 LOOP37 4 6 LOOP38 4 6 LOOP39 4 6 LOOP40 4 6 LOOP41 4 6 LOOP42 4 6 LOOP43 4 6 LOOP44 4 6 LOOP45 4 6 LOOP46 4 6 LOOP47 4 6 LOOP48 4 6 LOOP49 4 6 LOOP50 4 6 LOOP51 4 6 LOOP52 4 6 LOOP53 4 6 LOOP54 4 6 LOOP55 4 6 LOOP56 4 6 LOOP57 4 6 LOOP58 4 6 LOOP59 4 6 LOOP60 4 6 Crystallography ? ? Angstroms 1 G P 37.099 -27.121 -97.635 O3' 33.815 -30.863 -96.468 2 U P 32.846 -31.000 -97.737 O3' 28.034 -32.984 -97.308 3 C P 27.424 -33.033 -98.786 O3' 22.374 -32.322 -99.732 4 U P 21.910 -32.294 -101.275 O3' 19.131 -27.173 -101.720 5 A P 18.785 -26.882 -103.266 O3' 21.934 -22.241 -104.732 6 A P 21.016 -21.228 -105.560 O3' 21.861 -15.796 -104.307 7 G P 20.675 -15.414 -103.311 O3' 20.153 -16.692 -98.229 8 A P 20.731 -16.665 -96.717 O3' 20.602 -20.918 -92.735 9 C P 21.443 -20.037 -91.700 O3' 23.294 -22.884 -87.788 1 9 + + c 2 8 - - c 3 7 + + c 4 5 ! ! ! 1 9 3 SG1 4 6 1 172.055 279.965 2 171.258 281.444 3 170.461 282.923 4 169.601 284.855 5 170.756 286.625 6 172.870 286.616 7 174.011 284.837 8 174.808 283.358 9 175.605 281.879 1 3 411 412 413 AAG Crystallography ? ? Angstroms 1 A P 5.041 9.396 -106.528 O3' 9.150 5.400 -107.816 2 A P 10.177 4.190 -108.160 O3' 13.629 1.275 -104.376 3 G P 13.630 0.717 -102.864 O3' 10.343 2.778 -98.026 SG1 1 3 1 426.092 550.000 2 426.092 550.000 3 426.092 550.000 1 9 307 308 309 310 311 312 313 314 315 GUCU AAGAC LOOP1 4 6 LOOP2 4 6 LOOP3 4 6 LOOP4 4 6 LOOP5 4 6 LOOP6 4 6 LOOP7 4 6 LOOP8 4 6 LOOP9 4 6 LOOP10 4 6 LOOP11 4 6 LOOP12 4 6 LOOP13 4 6 LOOP14 4 6 LOOP15 4 6 LOOP16 4 6 LOOP17 4 6 LOOP18 4 6 LOOP19 4 6 LOOP20 4 6 LOOP21 4 6 LOOP22 4 6 LOOP23 4 6 LOOP24 4 6 LOOP25 4 6 LOOP26 4 6 LOOP27 4 6 LOOP28 4 6 LOOP29 4 6 LOOP30 4 6 LOOP31 4 6 LOOP32 4 6 LOOP33 4 6 LOOP34 4 6 LOOP35 4 6 LOOP36 4 6 LOOP37 4 6 LOOP38 4 6 LOOP39 4 6 LOOP40 4 6 LOOP41 4 6 LOOP42 4 6 LOOP43 4 6 LOOP44 4 6 LOOP45 4 6 LOOP46 4 6 LOOP47 4 6 LOOP48 4 6 LOOP49 4 6 LOOP50 4 6 LOOP51 4 6 LOOP52 4 6 LOOP53 4 6 LOOP54 4 6 LOOP55 4 6 LOOP56 4 6 LOOP57 4 6 LOOP58 4 6 LOOP59 4 6 LOOP60 4 6 Crystallography ? ? Angstroms 1 G P 31.674 7.045 -102.916 O3' 26.660 8.042 -103.086 2 U P 26.518 9.398 -103.927 O3' 22.391 12.550 -103.362 3 C P 22.572 13.736 -104.421 O3' 20.942 18.569 -103.481 4 U P 21.279 19.689 -104.591 O3' 24.095 23.782 -101.514 5 A P 24.699 24.888 -102.518 O3' 30.460 24.422 -102.080 6 A P 31.096 25.886 -101.971 O3' 35.368 26.285 -98.314 7 G P 34.724 26.912 -96.995 O3' 31.655 24.547 -93.429 8 A P 31.430 23.366 -92.347 O3' 26.593 20.271 -91.344 9 C P 27.344 19.361 -90.263 O3' 24.634 15.104 -89.095 1 9 + + c 2 8 - - c 3 7 + + c 4 5 ! ! ! 1 9 3 SG1 4 6 1 187.496 195.556 2 189.050 196.195 3 190.604 196.834 4 192.614 197.488 5 194.255 196.155 6 194.026 194.053 7 192.138 193.104 8 190.584 192.465 9 189.030 191.826 1 3 411 412 413 AAG Crystallography ? ? Angstroms 1 A P 47.655 49.036 -82.379 O3' 47.007 45.012 -86.611 2 A P 46.686 43.951 -87.798 O3' 44.768 38.412 -87.190 3 G P 43.793 37.524 -86.264 O3' 42.066 38.593 -80.404 SG1 1 3 1 426.092 550.000 2 426.092 550.000 3 426.092 550.000 1 9 307 308 309 310 311 312 313 314 315 GU CUAAGAC LOOP1 4 6 LOOP2 4 6 LOOP3 4 6 LOOP4 4 6 LOOP5 4 6 LOOP6 4 6 LOOP7 4 6 LOOP8 4 6 LOOP9 4 6 LOOP10 4 6 LOOP11 4 6 LOOP12 4 6 LOOP13 4 6 LOOP14 4 6 LOOP15 4 6 LOOP16 4 6 LOOP17 4 6 LOOP18 4 6 LOOP19 4 6 LOOP20 4 6 LOOP21 4 6 LOOP22 4 6 LOOP23 4 6 LOOP24 4 6 LOOP25 4 6 LOOP26 4 6 LOOP27 4 6 LOOP28 4 6 LOOP29 4 6 LOOP30 4 6 LOOP31 4 6 LOOP32 4 6 LOOP33 4 6 LOOP34 4 6 LOOP35 4 6 LOOP36 4 6 LOOP37 4 6 LOOP38 4 6 LOOP39 4 6 LOOP40 4 6 LOOP41 4 6 LOOP42 4 6 LOOP43 4 6 LOOP44 4 6 LOOP45 4 6 LOOP46 4 6 LOOP47 4 6 LOOP48 4 6 LOOP49 4 6 LOOP50 4 6 LOOP51 4 6 LOOP52 4 6 LOOP53 4 6 LOOP54 4 6 LOOP55 4 6 LOOP56 4 6 LOOP57 4 6 LOOP58 4 6 LOOP59 4 6 LOOP60 4 6 Crystallography ? ? Angstroms 1 G P 57.835 24.626 -87.710 O3' 56.176 29.152 -86.003 2 U P 57.475 30.089 -85.929 O3' 57.702 34.206 -82.723 3 C P 59.105 34.925 -82.999 O3' 61.778 37.326 -79.259 4 U P 63.224 37.920 -79.652 O3' 66.778 35.416 -75.747 5 A P 68.310 35.735 -76.133 O3' 70.667 30.630 -77.541 6 A P 72.103 30.510 -76.847 O3' 73.260 25.382 -74.808 7 G P 72.967 25.485 -73.242 O3' 68.301 25.601 -70.805 8 A P 66.871 24.908 -70.496 O3' 61.652 27.464 -70.047 9 C P 60.926 26.053 -69.852 O3' 55.793 26.415 -70.444 1 9 + + c 2 8 - - c 3 7 + + c 4 5 ! ! ! 1 9 3 SG1 4 6 1 122.021 154.866 2 121.933 153.188 3 121.845 151.511 4 121.894 149.397 5 123.696 148.291 6 125.603 149.203 7 125.872 151.300 8 125.960 152.978 9 126.048 154.656 1 3 411 412 413 AAG Crystallography ? ? Angstroms 1 A P 91.745 14.789 -53.161 O3' 89.738 16.071 -58.532 2 A P 89.159 16.567 -59.965 O3' 83.607 16.143 -61.895 3 G P 82.090 16.234 -61.360 O3' 79.997 15.226 -55.610 SG1 1 3 1 426.092 550.000 2 426.092 550.000 3 426.092 550.000 1 9 307 308 309 310 311 312 313 314 315 GUCUAAGAC LOOP1 4 6 LOOP2 4 6 LOOP3 4 6 LOOP4 4 6 LOOP5 4 6 LOOP6 4 6 LOOP7 4 6 LOOP8 4 6 LOOP9 4 6 LOOP10 4 6 LOOP11 4 6 LOOP12 4 6 LOOP13 4 6 LOOP14 4 6 LOOP15 4 6 LOOP16 4 6 LOOP17 4 6 LOOP18 4 6 LOOP19 4 6 LOOP20 4 6 LOOP21 4 6 LOOP22 4 6 LOOP23 4 6 LOOP24 4 6 LOOP25 4 6 LOOP26 4 6 LOOP27 4 6 LOOP28 4 6 LOOP29 4 6 LOOP30 4 6 LOOP31 4 6 LOOP32 4 6 LOOP33 4 6 LOOP34 4 6 LOOP35 4 6 LOOP36 4 6 LOOP37 4 6 LOOP38 4 6 LOOP39 4 6 LOOP40 4 6 LOOP41 4 6 LOOP42 4 6 LOOP43 4 6 LOOP44 4 6 LOOP45 4 6 LOOP46 4 6 LOOP47 4 6 LOOP48 4 6 LOOP49 4 6 LOOP50 4 6 LOOP51 4 6 LOOP52 4 6 LOOP53 4 6 LOOP54 4 6 LOOP55 4 6 LOOP56 4 6 LOOP57 4 6 LOOP58 4 6 LOOP59 4 6 LOOP60 4 6 Crystallography ? ? Angstroms 1 G P -86.189 -59.402 -26.218 O3' -84.229 -57.994 -30.728 2 U P -84.103 -59.343 -31.585 O3' -80.671 -59.790 -35.497 3 C P -80.906 -61.232 -36.150 O3' -77.037 -64.024 -38.184 4 U P -77.396 -65.502 -38.716 O3' -73.638 -68.898 -35.802 5 A P -74.006 -70.446 -36.055 O3' -75.697 -72.518 -30.913 6 A P -75.013 -73.943 -30.673 O3' -73.264 -74.804 -25.381 7 G P -71.695 -74.512 -25.413 O3' -69.255 -69.853 -25.654 8 A P -68.985 -68.385 -25.028 O3' -68.394 -63.316 -27.843 9 C P -68.278 -62.511 -26.466 O3' -68.849 -57.409 -27.148 1 9 + + c 2 8 - - c 3 7 + + c 4 5 ! ! ! 1 9 3 SG1 4 6 1 396.621 450.808 2 398.011 451.752 3 399.401 452.696 4 401.235 453.748 5 403.114 452.780 6 403.320 450.676 7 401.666 449.360 8 400.276 448.416 9 398.886 447.472 1 3 411 412 413 A AG Crystallography ? ? Angstroms 1 A P -52.246 -92.597 -12.570 O3' -57.536 -90.683 -14.263 2 A P -58.940 -90.137 -14.870 O3' -60.891 -84.576 -14.866 3 G P -60.351 -83.065 -15.013 O3' -54.666 -80.900 -13.802 SG1 1 3 1 426.092 550.000 2 426.092 550.000 3 426.092 550.000 1 9 307 308 309 310 311 312 313 314 315 GUCUAAGA C LOOP1 4 6 LOOP2 4 6 LOOP3 4 6 LOOP4 4 6 LOOP5 4 6 LOOP6 4 6 LOOP7 4 6 LOOP8 4 6 LOOP9 4 6 LOOP10 4 6 LOOP11 4 6 LOOP12 4 6 LOOP13 4 6 LOOP14 4 6 LOOP15 4 6 LOOP16 4 6 LOOP17 4 6 LOOP18 4 6 LOOP19 4 6 LOOP20 4 6 LOOP21 4 6 LOOP22 4 6 LOOP23 4 6 LOOP24 4 6 LOOP25 4 6 LOOP26 4 6 LOOP27 4 6 LOOP28 4 6 LOOP29 4 6 LOOP30 4 6 LOOP31 4 6 LOOP32 4 6 LOOP33 4 6 LOOP34 4 6 LOOP35 4 6 LOOP36 4 6 LOOP37 4 6 LOOP38 4 6 LOOP39 4 6 LOOP40 4 6 LOOP41 4 6 LOOP42 4 6 LOOP43 4 6 LOOP44 4 6 LOOP45 4 6 LOOP46 4 6 LOOP47 4 6 LOOP48 4 6 LOOP49 4 6 LOOP50 4 6 LOOP51 4 6 LOOP52 4 6 LOOP53 4 6 LOOP54 4 6 LOOP55 4 6 LOOP56 4 6 LOOP57 4 6 LOOP58 4 6 LOOP59 4 6 LOOP60 4 6 Crystallography ? ? Angstroms 1 G P -72.843 -79.608 -0.955 O3' -68.534 -81.845 -2.561 2 U P -68.367 -83.161 -1.659 O3' -63.695 -85.352 -0.849 3 C P -63.953 -86.672 0.016 O3' -60.554 -88.387 3.540 4 U P -60.984 -89.672 4.414 O3' -60.402 -87.776 9.910 5 A P -61.003 -88.876 10.924 O3' -65.609 -86.374 13.399 6 A P -65.578 -86.663 14.971 O3' -67.138 -82.280 18.158 7 G P -65.771 -81.633 18.665 O3' -62.365 -78.676 15.946 8 A P -62.060 -77.353 15.068 O3' -58.705 -76.869 10.325 9 C P -59.098 -75.329 10.148 O3' -57.776 -73.518 5.480 1 9 + + c 2 8 - - c 3 7 + + c 4 5 ! ! ! 1 9 3 SG1 4 6 1 364.501 475.999 2 364.598 477.677 3 364.694 479.354 4 364.975 481.450 5 366.887 482.352 6 368.682 481.236 7 368.720 479.122 8 368.624 477.445 9 368.527 475.768 1 3 411 412 413 AAG Crystallography ? ? Angstroms 1 A P -61.742 -73.864 46.838 O3' -64.611 -76.040 42.194 2 A P -65.280 -76.725 40.884 O3' -65.301 -74.601 35.386 3 G P -64.365 -73.782 34.362 O3' -59.784 -69.821 35.702 SG1 1 3 1 426.092 550.000 2 426.092 550.000 3 426.092 550.000 1 9 307 308 309 310 311 312 313 314 315 GUCUAA GAC LOOP1 4 6 LOOP2 4 6 LOOP3 4 6 LOOP4 4 6 LOOP5 4 6 LOOP6 4 6 LOOP7 4 6 LOOP8 4 6 LOOP9 4 6 LOOP10 4 6 LOOP11 4 6 LOOP12 4 6 LOOP13 4 6 LOOP14 4 6 LOOP15 4 6 LOOP16 4 6 LOOP17 4 6 LOOP18 4 6 LOOP19 4 6 LOOP20 4 6 LOOP21 4 6 LOOP22 4 6 LOOP23 4 6 LOOP24 4 6 LOOP25 4 6 LOOP26 4 6 LOOP27 4 6 LOOP28 4 6 LOOP29 4 6 LOOP30 4 6 LOOP31 4 6 LOOP32 4 6 LOOP33 4 6 LOOP34 4 6 LOOP35 4 6 LOOP36 4 6 LOOP37 4 6 LOOP38 4 6 LOOP39 4 6 LOOP40 4 6 LOOP41 4 6 LOOP42 4 6 LOOP43 4 6 LOOP44 4 6 LOOP45 4 6 LOOP46 4 6 LOOP47 4 6 LOOP48 4 6 LOOP49 4 6 LOOP50 4 6 LOOP51 4 6 LOOP52 4 6 LOOP53 4 6 LOOP54 4 6 LOOP55 4 6 LOOP56 4 6 LOOP57 4 6 LOOP58 4 6 LOOP59 4 6 LOOP60 4 6 Crystallography ? ? Angstroms 1 G P -80.764 -65.038 29.862 O3' -77.075 -65.987 33.275 2 U P -77.775 -65.869 34.712 O3' -75.028 -64.743 39.010 3 C P -76.054 -64.798 40.237 O3' -75.606 -61.698 44.371 4 U P -76.765 -61.786 45.487 O3' -78.602 -56.256 45.915 5 A P -79.920 -56.198 46.842 O3' -84.223 -54.524 43.338 6 A P -85.092 -53.403 44.077 O3' -86.771 -49.195 40.720 7 G P -85.745 -48.007 41.004 O3' -80.756 -47.554 39.380 8 A P -79.684 -47.492 38.170 O3' -74.385 -49.906 37.921 9 C P -74.179 -49.412 36.416 O3' -70.189 -51.789 34.122 1 9 + + c 2 8 - - c 3 7 + + c 4 5 ! ! ! 1 9 3 SG1 4 6 1 408.183 432.203 2 408.350 433.875 3 408.518 435.546 4 408.887 437.628 5 410.836 438.448 6 412.582 437.257 7 412.530 435.144 8 412.363 433.472 9 412.195 431.800 1 3 411 412 413 AAG Crystallography ? ? Angstroms 1 A P -94.860 -20.280 45.300 O3' -95.393 -26.039 44.264 2 A P -95.449 -27.654 44.096 O3' -92.030 -30.988 40.644 3 G P -90.514 -31.081 40.106 O3' -86.389 -26.492 39.481 SG1 1 3 1 426.092 550.000 2 426.092 550.000 3 426.092 550.000 1 9 307 308 309 310 311 312 313 314 315 GUCU AAGAC LOOP1 4 6 LOOP2 4 6 LOOP3 4 6 LOOP4 4 6 LOOP5 4 6 LOOP6 4 6 LOOP7 4 6 LOOP8 4 6 LOOP9 4 6 LOOP10 4 6 LOOP11 4 6 LOOP12 4 6 LOOP13 4 6 LOOP14 4 6 LOOP15 4 6 LOOP16 4 6 LOOP17 4 6 LOOP18 4 6 LOOP19 4 6 LOOP20 4 6 LOOP21 4 6 LOOP22 4 6 LOOP23 4 6 LOOP24 4 6 LOOP25 4 6 LOOP26 4 6 LOOP27 4 6 LOOP28 4 6 LOOP29 4 6 LOOP30 4 6 LOOP31 4 6 LOOP32 4 6 LOOP33 4 6 LOOP34 4 6 LOOP35 4 6 LOOP36 4 6 LOOP37 4 6 LOOP38 4 6 LOOP39 4 6 LOOP40 4 6 LOOP41 4 6 LOOP42 4 6 LOOP43 4 6 LOOP44 4 6 LOOP45 4 6 LOOP46 4 6 LOOP47 4 6 LOOP48 4 6 LOOP49 4 6 LOOP50 4 6 LOOP51 4 6 LOOP52 4 6 LOOP53 4 6 LOOP54 4 6 LOOP55 4 6 LOOP56 4 6 LOOP57 4 6 LOOP58 4 6 LOOP59 4 6 LOOP60 4 6 Crystallography ? ? Angstroms 1 G P -99.004 -35.828 23.644 O3' -98.049 -32.335 27.255 2 U P -99.325 -31.364 27.266 O3' -99.007 -26.446 28.999 3 C P -100.486 -25.839 28.929 O3' -101.390 -20.840 27.884 4 U P -102.929 -20.384 27.743 O3' -103.085 -17.898 22.456 5 A P -104.614 -17.573 22.061 O3' -105.816 -20.983 17.529 6 A P -106.586 -20.126 16.421 O3' -105.030 -21.270 11.123 7 G P -104.013 -20.103 10.732 O3' -99.012 -19.495 12.261 8 A P -97.501 -20.069 12.352 O3' -93.764 -19.689 16.808 9 C P -92.680 -20.575 16.036 O3' -88.934 -22.250 19.197 1 9 + + c 2 8 - - c 3 7 + + c 4 5 ! ! ! 1 9 3 SG1 4 6 1 467.548 380.187 2 469.071 380.898 3 470.593 381.610 4 472.570 382.357 5 474.272 381.103 6 474.142 378.993 7 472.300 377.956 8 470.778 377.245 9 469.256 376.533 1 3 411 412 413 AAG Crystallography ? ? Angstroms 1 A P -105.832 -5.896 -15.059 O3' -107.343 -9.779 -10.916 2 A P -107.754 -10.738 -9.671 O3' -104.140 -14.008 -6.359 3 G P -102.662 -13.973 -5.718 O3' -97.715 -10.792 -7.687 SG1 1 3 1 426.092 550.000 2 426.092 550.000 3 426.092 550.000 1 9 307 308 309 310 311 312 313 314 315 GU CUAAGAC LOOP1 4 6 LOOP2 4 6 LOOP3 4 6 LOOP4 4 6 LOOP5 4 6 LOOP6 4 6 LOOP7 4 6 LOOP8 4 6 LOOP9 4 6 LOOP10 4 6 LOOP11 4 6 LOOP12 4 6 LOOP13 4 6 LOOP14 4 6 LOOP15 4 6 LOOP16 4 6 LOOP17 4 6 LOOP18 4 6 LOOP19 4 6 LOOP20 4 6 LOOP21 4 6 LOOP22 4 6 LOOP23 4 6 LOOP24 4 6 LOOP25 4 6 LOOP26 4 6 LOOP27 4 6 LOOP28 4 6 LOOP29 4 6 LOOP30 4 6 LOOP31 4 6 LOOP32 4 6 LOOP33 4 6 LOOP34 4 6 LOOP35 4 6 LOOP36 4 6 LOOP37 4 6 LOOP38 4 6 LOOP39 4 6 LOOP40 4 6 LOOP41 4 6 LOOP42 4 6 LOOP43 4 6 LOOP44 4 6 LOOP45 4 6 LOOP46 4 6 LOOP47 4 6 LOOP48 4 6 LOOP49 4 6 LOOP50 4 6 LOOP51 4 6 LOOP52 4 6 LOOP53 4 6 LOOP54 4 6 LOOP55 4 6 LOOP56 4 6 LOOP57 4 6 LOOP58 4 6 LOOP59 4 6 LOOP60 4 6 Crystallography ? ? Angstroms 1 G P -102.357 -32.344 -11.016 O3' -102.471 -27.395 -12.300 2 U P -103.236 -27.330 -13.708 O3' -102.494 -23.385 -17.050 3 C P -103.485 -23.636 -18.281 O3' -102.274 -22.278 -23.138 4 U P -103.319 -22.680 -24.298 O3' -100.017 -25.711 -28.047 5 A P -100.958 -26.380 -29.172 O3' -100.546 -32.104 -28.360 6 A P -100.357 -32.820 -29.776 O3' -96.682 -37.097 -29.729 7 G P -95.330 -36.485 -30.317 O3' -91.903 -33.276 -27.932 8 A P -90.889 -32.982 -26.705 O3' -90.061 -27.976 -23.836 9 C P -89.033 -28.672 -22.827 O3' -88.106 -25.724 -18.670 1 9 + + c 2 8 - - c 3 7 + + c 4 5 ! ! ! 1 9 3 SG1 4 6 1 461.384 387.143 2 463.063 387.199 3 464.743 387.256 4 466.844 387.487 5 467.791 389.377 6 466.719 391.198 7 464.607 391.286 8 462.927 391.230 9 461.248 391.173 1 3 411 412 413 AAG Crystallography ? ? Angstroms 1 A P -79.494 -50.590 -50.824 O3' -83.946 -49.730 -47.086 2 A P -85.190 -49.354 -46.114 O3' -84.894 -47.127 -40.666 3 G P -84.020 -46.101 -39.784 O3' -78.109 -44.418 -40.618 SG1 1 3 1 426.092 550.000 2 426.092 550.000 3 426.092 550.000 1 9 307 308 309 310 311 312 313 314 315 GUCUAAGAC LOOP1 4 6 LOOP2 4 6 LOOP3 4 6 LOOP4 4 6 LOOP5 4 6 LOOP6 4 6 LOOP7 4 6 LOOP8 4 6 LOOP9 4 6 LOOP10 4 6 LOOP11 4 6 LOOP12 4 6 LOOP13 4 6 LOOP14 4 6 LOOP15 4 6 LOOP16 4 6 LOOP17 4 6 LOOP18 4 6 LOOP19 4 6 LOOP20 4 6 LOOP21 4 6 LOOP22 4 6 LOOP23 4 6 LOOP24 4 6 LOOP25 4 6 LOOP26 4 6 LOOP27 4 6 LOOP28 4 6 LOOP29 4 6 LOOP30 4 6 LOOP31 4 6 LOOP32 4 6 LOOP33 4 6 LOOP34 4 6 LOOP35 4 6 LOOP36 4 6 LOOP37 4 6 LOOP38 4 6 LOOP39 4 6 LOOP40 4 6 LOOP41 4 6 LOOP42 4 6 LOOP43 4 6 LOOP44 4 6 LOOP45 4 6 LOOP46 4 6 LOOP47 4 6 LOOP48 4 6 LOOP49 4 6 LOOP50 4 6 LOOP51 4 6 LOOP52 4 6 LOOP53 4 6 LOOP54 4 6 LOOP55 4 6 LOOP56 4 6 LOOP57 4 6 LOOP58 4 6 LOOP59 4 6 LOOP60 4 6 Crystallography ? ? Angstroms 1 G P -12.815 -103.975 -25.874 O3' -13.820 -103.806 -20.862 2 U P -15.222 -104.562 -20.676 O3' -18.336 -103.591 -16.597 3 C P -19.580 -104.590 -16.723 O3' -24.353 -103.290 -15.164 4 U P -25.534 -104.352 -15.442 O3' -29.447 -101.213 -18.438 5 A P -30.608 -102.187 -18.989 O3' -30.118 -102.099 -24.764 6 A P -31.573 -101.945 -25.409 O3' -31.766 -98.516 -29.882 7 G P -32.318 -97.130 -29.315 O3' -29.757 -93.537 -26.442 8 A P -28.516 -92.511 -26.274 O3' -25.370 -91.413 -21.492 9 C P -24.402 -90.428 -22.299 O3' -20.086 -89.350 -19.646 1 9 + + c 2 8 - - c 3 7 + + c 4 5 ! ! ! 1 9 3 SG1 4 6 1 240.435 492.748 2 240.042 494.382 3 239.650 496.016 4 239.312 498.103 5 240.881 499.519 6 242.923 498.970 7 243.570 496.958 8 243.963 495.324 9 244.356 493.691 1 3 411 412 413 A AG Crystallography ? ? Angstroms 1 A P -53.586 -82.046 -43.115 O3' -49.806 -86.454 -42.217 2 A P -48.813 -87.678 -41.827 O3' -43.249 -87.275 -39.928 3 G P -42.310 -86.347 -39.004 O3' -43.048 -80.348 -37.612 SG1 1 3 1 426.092 550.000 2 426.092 550.000 3 426.092 550.000 1 9 307 308 309 310 311 312 313 314 315 GUCUAAGA C LOOP1 4 6 LOOP2 4 6 LOOP3 4 6 LOOP4 4 6 LOOP5 4 6 LOOP6 4 6 LOOP7 4 6 LOOP8 4 6 LOOP9 4 6 LOOP10 4 6 LOOP11 4 6 LOOP12 4 6 LOOP13 4 6 LOOP14 4 6 LOOP15 4 6 LOOP16 4 6 LOOP17 4 6 LOOP18 4 6 LOOP19 4 6 LOOP20 4 6 LOOP21 4 6 LOOP22 4 6 LOOP23 4 6 LOOP24 4 6 LOOP25 4 6 LOOP26 4 6 LOOP27 4 6 LOOP28 4 6 LOOP29 4 6 LOOP30 4 6 LOOP31 4 6 LOOP32 4 6 LOOP33 4 6 LOOP34 4 6 LOOP35 4 6 LOOP36 4 6 LOOP37 4 6 LOOP38 4 6 LOOP39 4 6 LOOP40 4 6 LOOP41 4 6 LOOP42 4 6 LOOP43 4 6 LOOP44 4 6 LOOP45 4 6 LOOP46 4 6 LOOP47 4 6 LOOP48 4 6 LOOP49 4 6 LOOP50 4 6 LOOP51 4 6 LOOP52 4 6 LOOP53 4 6 LOOP54 4 6 LOOP55 4 6 LOOP56 4 6 LOOP57 4 6 LOOP58 4 6 LOOP59 4 6 LOOP60 4 6 Crystallography ? ? Angstroms 1 G P -29.514 -89.302 -52.902 O3' -33.937 -87.252 -51.355 2 U P -34.868 -87.199 -52.660 O3' -38.799 -83.785 -53.080 3 C P -39.532 -84.098 -54.467 O3' -41.720 -80.385 -57.353 4 U P -42.334 -80.825 -58.777 O3' -39.615 -77.273 -62.535 5 A P -39.955 -77.725 -64.045 O3' -34.937 -79.547 -66.303 6 A P -34.778 -78.945 -67.775 O3' -29.544 -77.264 -69.028 7 G P -29.559 -75.681 -68.824 O3' -29.538 -72.982 -64.302 8 A P -28.829 -72.632 -62.891 O3' -31.356 -71.749 -57.712 9 C P -29.935 -71.593 -56.994 O3' -30.330 -71.874 -51.838 1 9 + + c 2 8 - - c 3 7 + + c 4 5 ! ! ! 1 9 3 SG1 4 6 1 269.769 459.324 2 270.571 460.801 3 271.372 462.277 4 272.518 464.054 5 274.632 464.056 6 275.782 462.282 7 274.916 460.354 8 274.115 458.877 9 273.313 457.400 1 3 411 412 413 AAG Crystallography ? ? Angstroms 1 A P -17.752 -57.317 -88.665 O3' -19.334 -62.486 -86.364 2 A P -19.910 -63.855 -85.707 O3' -19.594 -65.491 -80.054 3 G P -19.655 -64.867 -78.571 O3' -18.325 -59.073 -76.800 SG1 1 3 1 426.092 550.000 2 426.092 550.000 3 426.092 550.000 1 9 307 308 309 310 311 312 313 314 315 GUCUAA GAC LOOP1 4 6 LOOP2 4 6 LOOP3 4 6 LOOP4 4 6 LOOP5 4 6 LOOP6 4 6 LOOP7 4 6 LOOP8 4 6 LOOP9 4 6 LOOP10 4 6 LOOP11 4 6 LOOP12 4 6 LOOP13 4 6 LOOP14 4 6 LOOP15 4 6 LOOP16 4 6 LOOP17 4 6 LOOP18 4 6 LOOP19 4 6 LOOP20 4 6 LOOP21 4 6 LOOP22 4 6 LOOP23 4 6 LOOP24 4 6 LOOP25 4 6 LOOP26 4 6 LOOP27 4 6 LOOP28 4 6 LOOP29 4 6 LOOP30 4 6 LOOP31 4 6 LOOP32 4 6 LOOP33 4 6 LOOP34 4 6 LOOP35 4 6 LOOP36 4 6 LOOP37 4 6 LOOP38 4 6 LOOP39 4 6 LOOP40 4 6 LOOP41 4 6 LOOP42 4 6 LOOP43 4 6 LOOP44 4 6 LOOP45 4 6 LOOP46 4 6 LOOP47 4 6 LOOP48 4 6 LOOP49 4 6 LOOP50 4 6 LOOP51 4 6 LOOP52 4 6 LOOP53 4 6 LOOP54 4 6 LOOP55 4 6 LOOP56 4 6 LOOP57 4 6 LOOP58 4 6 LOOP59 4 6 LOOP60 4 6 Crystallography ? ? Angstroms 1 G P -5.425 -77.190 -75.211 O3' -7.154 -73.008 -77.593 2 U P -6.328 -72.918 -78.964 O3' -5.643 -68.379 -81.456 3 C P -4.852 -68.713 -82.807 O3' -1.431 -65.427 -84.905 4 U P -0.630 -65.932 -86.210 O3' 4.964 -65.262 -84.661 5 A P 5.914 -65.926 -85.781 O3' 8.526 -70.392 -83.167 6 A P 10.079 -70.382 -83.546 O3' 13.507 -71.704 -79.269 7 G P 14.050 -70.304 -78.728 O3' 11.502 -66.730 -75.819 8 A P 10.698 -66.348 -74.467 O3' 5.991 -62.956 -73.908 9 C P 5.901 -63.262 -72.341 O3' 1.341 -61.824 -70.348 1 9 + + c 2 8 - - c 3 7 + + c 4 5 ! ! ! 1 9 3 SG1 4 6 1 201.245 418.378 2 202.184 419.772 3 203.123 421.165 4 204.433 422.824 5 206.538 422.624 6 207.513 420.749 7 206.467 418.911 8 205.528 417.518 9 204.589 416.125 1 3 411 412 413 AAG Crystallography ? ? Angstroms 1 A P 42.615 -65.936 -72.790 O3' 37.857 -68.907 -74.537 2 A P 36.509 -69.609 -75.108 O3' 31.139 -69.493 -72.683 3 G P 30.163 -68.510 -71.861 O3' 31.723 -63.719 -68.245 SG1 1 3 1 426.092 550.000 2 426.092 550.000 3 426.092 550.000 1 9 307 308 309 310 311 312 313 314 315 GUCU AAGAC LOOP1 4 6 LOOP2 4 6 LOOP3 4 6 LOOP4 4 6 LOOP5 4 6 LOOP6 4 6 LOOP7 4 6 LOOP8 4 6 LOOP9 4 6 LOOP10 4 6 LOOP11 4 6 LOOP12 4 6 LOOP13 4 6 LOOP14 4 6 LOOP15 4 6 LOOP16 4 6 LOOP17 4 6 LOOP18 4 6 LOOP19 4 6 LOOP20 4 6 LOOP21 4 6 LOOP22 4 6 LOOP23 4 6 LOOP24 4 6 LOOP25 4 6 LOOP26 4 6 LOOP27 4 6 LOOP28 4 6 LOOP29 4 6 LOOP30 4 6 LOOP31 4 6 LOOP32 4 6 LOOP33 4 6 LOOP34 4 6 LOOP35 4 6 LOOP36 4 6 LOOP37 4 6 LOOP38 4 6 LOOP39 4 6 LOOP40 4 6 LOOP41 4 6 LOOP42 4 6 LOOP43 4 6 LOOP44 4 6 LOOP45 4 6 LOOP46 4 6 LOOP47 4 6 LOOP48 4 6 LOOP49 4 6 LOOP50 4 6 LOOP51 4 6 LOOP52 4 6 LOOP53 4 6 LOOP54 4 6 LOOP55 4 6 LOOP56 4 6 LOOP57 4 6 LOOP58 4 6 LOOP59 4 6 LOOP60 4 6 Crystallography ? ? Angstroms 1 G P 26.161 -84.378 -61.971 O3' 29.515 -80.759 -63.315 2 U P 30.957 -81.456 -63.238 O3' 35.311 -78.663 -62.513 3 C P 36.533 -79.695 -62.578 O3' 40.836 -79.087 -59.746 4 U P 41.945 -80.253 -59.831 O3' 42.683 -81.778 -54.238 5 A P 43.611 -83.093 -54.159 O3' 40.207 -87.285 -52.050 6 A P 41.008 -88.092 -50.926 O3' 37.892 -89.521 -46.449 7 G P 38.243 -88.431 -45.338 O3' 36.646 -83.420 -45.076 8 A P 35.441 -82.342 -45.006 O3' 35.059 -77.186 -47.697 9 C P 33.582 -76.948 -47.131 O3' 31.159 -73.091 -49.596 1 9 + + c 2 8 - - c 3 7 + + c 4 5 ! ! ! 1 9 3 SG1 4 6 1 131.883 425.667 2 130.352 426.362 3 128.822 427.056 4 126.969 428.072 5 126.816 430.180 6 128.503 431.454 7 130.489 430.728 8 132.019 430.034 9 133.549 429.340 1 3 411 412 413 AAG Crystallography ? ? Angstroms 1 A P 44.090 -95.991 -17.428 O3' 42.731 -96.843 -23.081 2 A P 42.473 -96.988 -24.677 O3' 38.839 -93.751 -28.000 3 G P 38.297 -92.241 -28.148 O3' 37.931 -87.864 -23.770 SG1 1 3 1 426.092 550.000 2 426.092 550.000 3 426.092 550.000 1 9 307 308 309 310 311 312 313 314 315 GU CUAAGAC LOOP1 4 6 LOOP2 4 6 LOOP3 4 6 LOOP4 4 6 LOOP5 4 6 LOOP6 4 6 LOOP7 4 6 LOOP8 4 6 LOOP9 4 6 LOOP10 4 6 LOOP11 4 6 LOOP12 4 6 LOOP13 4 6 LOOP14 4 6 LOOP15 4 6 LOOP16 4 6 LOOP17 4 6 LOOP18 4 6 LOOP19 4 6 LOOP20 4 6 LOOP21 4 6 LOOP22 4 6 LOOP23 4 6 LOOP24 4 6 LOOP25 4 6 LOOP26 4 6 LOOP27 4 6 LOOP28 4 6 LOOP29 4 6 LOOP30 4 6 LOOP31 4 6 LOOP32 4 6 LOOP33 4 6 LOOP34 4 6 LOOP35 4 6 LOOP36 4 6 LOOP37 4 6 LOOP38 4 6 LOOP39 4 6 LOOP40 4 6 LOOP41 4 6 LOOP42 4 6 LOOP43 4 6 LOOP44 4 6 LOOP45 4 6 LOOP46 4 6 LOOP47 4 6 LOOP48 4 6 LOOP49 4 6 LOOP50 4 6 LOOP51 4 6 LOOP52 4 6 LOOP53 4 6 LOOP54 4 6 LOOP55 4 6 LOOP56 4 6 LOOP57 4 6 LOOP58 4 6 LOOP59 4 6 LOOP60 4 6 Crystallography ? ? Angstroms 1 G P 21.593 -100.932 -31.479 O3' 25.396 -99.794 -28.254 2 U P 25.461 -101.014 -27.214 O3' 27.467 -100.425 -22.427 3 C P 27.431 -101.868 -21.736 O3' 26.669 -102.486 -16.643 4 U P 26.554 -103.998 -16.093 O3' 21.416 -103.997 -13.311 5 A P 21.038 -105.504 -12.879 O3' 16.323 -106.881 -15.956 6 A P 15.265 -107.598 -14.996 O3' 9.911 -106.092 -15.926 7 G P 9.586 -105.011 -14.799 O3' 11.147 -99.987 -14.559 8 A P 11.206 -98.512 -15.221 O3' 15.676 -94.773 -15.303 9 C P 14.854 -93.738 -16.204 O3' 17.916 -90.103 -18.262 1 9 + + c 2 8 - - c 3 7 + + c 4 5 ! ! ! 1 9 3 SG1 4 6 1 155.072 472.692 2 153.664 473.609 3 152.255 474.525 4 150.576 475.809 5 150.742 477.916 6 152.601 478.921 7 154.455 477.905 8 155.863 476.989 9 157.272 476.072 1 3 411 412 413 AAG Crystallography ? ? Angstroms 1 A P -15.366 -105.948 0.912 O3' -11.447 -107.687 -3.106 2 A P -10.259 -108.155 -4.108 O3' -7.136 -104.740 -7.757 3 G P -6.494 -103.265 -7.842 O3' -8.280 -98.142 -4.837 SG1 1 3 1 426.092 550.000 2 426.092 550.000 3 426.092 550.000 1 9 307 308 309 310 311 312 313 314 315 GUCUAAGAC LOOP1 4 6 LOOP2 4 6 LOOP3 4 6 LOOP4 4 6 LOOP5 4 6 LOOP6 4 6 LOOP7 4 6 LOOP8 4 6 LOOP9 4 6 LOOP10 4 6 LOOP11 4 6 LOOP12 4 6 LOOP13 4 6 LOOP14 4 6 LOOP15 4 6 LOOP16 4 6 LOOP17 4 6 LOOP18 4 6 LOOP19 4 6 LOOP20 4 6 LOOP21 4 6 LOOP22 4 6 LOOP23 4 6 LOOP24 4 6 LOOP25 4 6 LOOP26 4 6 LOOP27 4 6 LOOP28 4 6 LOOP29 4 6 LOOP30 4 6 LOOP31 4 6 LOOP32 4 6 LOOP33 4 6 LOOP34 4 6 LOOP35 4 6 LOOP36 4 6 LOOP37 4 6 LOOP38 4 6 LOOP39 4 6 LOOP40 4 6 LOOP41 4 6 LOOP42 4 6 LOOP43 4 6 LOOP44 4 6 LOOP45 4 6 LOOP46 4 6 LOOP47 4 6 LOOP48 4 6 LOOP49 4 6 LOOP50 4 6 LOOP51 4 6 LOOP52 4 6 LOOP53 4 6 LOOP54 4 6 LOOP55 4 6 LOOP56 4 6 LOOP57 4 6 LOOP58 4 6 LOOP59 4 6 LOOP60 4 6 Crystallography ? ? Angstroms 1 G P 26.161 84.378 61.971 O3' 29.515 80.759 63.315 2 U P 30.957 81.456 63.238 O3' 35.311 78.663 62.513 3 C P 36.533 79.695 62.578 O3' 40.836 79.087 59.746 4 U P 41.945 80.253 59.831 O3' 42.683 81.778 54.238 5 A P 43.611 83.093 54.159 O3' 40.207 87.285 52.050 6 A P 41.008 88.092 50.926 O3' 37.892 89.521 46.449 7 G P 38.243 88.431 45.338 O3' 36.646 83.420 45.076 8 A P 35.441 82.342 45.006 O3' 35.059 77.186 47.697 9 C P 33.582 76.948 47.131 O3' 31.159 73.091 49.596 1 9 + + c 2 8 - - c 3 7 + + c 4 5 ! ! ! 1 9 3 SG1 4 6 1 236.349 35.818 2 235.371 34.452 3 234.393 33.085 4 233.296 31.278 5 234.217 29.376 6 236.315 29.117 7 237.672 30.738 8 238.650 32.105 9 239.628 33.471 1 3 411 412 413 A AG Crystallography ? ? Angstroms 1 A P 44.090 95.991 17.428 O3' 42.731 96.843 23.081 2 A P 42.473 96.988 24.677 O3' 38.839 93.751 28.000 3 G P 38.297 92.241 28.148 O3' 37.931 87.864 23.770 SG1 1 3 1 426.092 550.000 2 426.092 550.000 3 426.092 550.000 1 9 307 308 309 310 311 312 313 314 315 GUCUAAGA C LOOP1 4 6 LOOP2 4 6 LOOP3 4 6 LOOP4 4 6 LOOP5 4 6 LOOP6 4 6 LOOP7 4 6 LOOP8 4 6 LOOP9 4 6 LOOP10 4 6 LOOP11 4 6 LOOP12 4 6 LOOP13 4 6 LOOP14 4 6 LOOP15 4 6 LOOP16 4 6 LOOP17 4 6 LOOP18 4 6 LOOP19 4 6 LOOP20 4 6 LOOP21 4 6 LOOP22 4 6 LOOP23 4 6 LOOP24 4 6 LOOP25 4 6 LOOP26 4 6 LOOP27 4 6 LOOP28 4 6 LOOP29 4 6 LOOP30 4 6 LOOP31 4 6 LOOP32 4 6 LOOP33 4 6 LOOP34 4 6 LOOP35 4 6 LOOP36 4 6 LOOP37 4 6 LOOP38 4 6 LOOP39 4 6 LOOP40 4 6 LOOP41 4 6 LOOP42 4 6 LOOP43 4 6 LOOP44 4 6 LOOP45 4 6 LOOP46 4 6 LOOP47 4 6 LOOP48 4 6 LOOP49 4 6 LOOP50 4 6 LOOP51 4 6 LOOP52 4 6 LOOP53 4 6 LOOP54 4 6 LOOP55 4 6 LOOP56 4 6 LOOP57 4 6 LOOP58 4 6 LOOP59 4 6 LOOP60 4 6 Crystallography ? ? Angstroms 1 G P 21.593 100.932 31.479 O3' 25.396 99.794 28.254 2 U P 25.461 101.014 27.214 O3' 27.467 100.425 22.427 3 C P 27.431 101.868 21.736 O3' 26.669 102.486 16.643 4 U P 26.554 103.998 16.093 O3' 21.416 103.997 13.311 5 A P 21.038 105.504 12.879 O3' 16.323 106.881 15.956 6 A P 15.265 107.598 14.996 O3' 9.911 106.092 15.926 7 G P 9.586 105.011 14.799 O3' 11.147 99.987 14.559 8 A P 11.206 98.512 15.221 O3' 15.676 94.773 15.303 9 C P 14.854 93.738 16.204 O3' 17.916 90.103 18.262 1 9 + + c 2 8 - - c 3 7 + + c 4 5 ! ! ! 1 9 3 SG1 4 6 1 279.945 6.689 2 279.183 5.191 3 278.422 3.693 4 277.609 1.742 5 278.807 0.000 6 280.920 0.060 7 282.017 1.866 8 282.778 3.364 9 283.540 4.862 1 3 411 412 413 AAG Crystallography ? ? Angstroms 1 A P -15.366 105.948 -0.912 O3' -11.447 107.687 3.106 2 A P -10.259 108.155 4.108 O3' -7.136 104.740 7.757 3 G P -6.494 103.265 7.842 O3' -8.280 98.142 4.837 SG1 1 3 1 426.092 550.000 2 426.092 550.000 3 426.092 550.000 1 9 307 308 309 310 311 312 313 314 315 GUCUAA GAC LOOP1 4 6 LOOP2 4 6 LOOP3 4 6 LOOP4 4 6 LOOP5 4 6 LOOP6 4 6 LOOP7 4 6 LOOP8 4 6 LOOP9 4 6 LOOP10 4 6 LOOP11 4 6 LOOP12 4 6 LOOP13 4 6 LOOP14 4 6 LOOP15 4 6 LOOP16 4 6 LOOP17 4 6 LOOP18 4 6 LOOP19 4 6 LOOP20 4 6 LOOP21 4 6 LOOP22 4 6 LOOP23 4 6 LOOP24 4 6 LOOP25 4 6 LOOP26 4 6 LOOP27 4 6 LOOP28 4 6 LOOP29 4 6 LOOP30 4 6 LOOP31 4 6 LOOP32 4 6 LOOP33 4 6 LOOP34 4 6 LOOP35 4 6 LOOP36 4 6 LOOP37 4 6 LOOP38 4 6 LOOP39 4 6 LOOP40 4 6 LOOP41 4 6 LOOP42 4 6 LOOP43 4 6 LOOP44 4 6 LOOP45 4 6 LOOP46 4 6 LOOP47 4 6 LOOP48 4 6 LOOP49 4 6 LOOP50 4 6 LOOP51 4 6 LOOP52 4 6 LOOP53 4 6 LOOP54 4 6 LOOP55 4 6 LOOP56 4 6 LOOP57 4 6 LOOP58 4 6 LOOP59 4 6 LOOP60 4 6 Crystallography ? ? Angstroms 1 G P -12.815 103.975 25.874 O3' -13.820 103.806 20.862 2 U P -15.222 104.562 20.676 O3' -18.336 103.591 16.597 3 C P -19.580 104.590 16.723 O3' -24.353 103.290 15.164 4 U P -25.534 104.352 15.442 O3' -29.447 101.213 18.438 5 A P -30.608 102.187 18.989 O3' -30.118 102.099 24.764 6 A P -31.573 101.945 25.409 O3' -31.766 98.516 29.882 7 G P -32.318 97.130 29.315 O3' -29.757 93.537 26.442 8 A P -28.516 92.511 26.274 O3' -25.370 91.413 21.492 9 C P -24.402 90.428 22.299 O3' -20.086 89.350 19.646 1 9 + + c 2 8 - - c 3 7 + + c 4 5 ! ! ! 1 9 3 SG1 4 6 1 363.898 32.004 2 364.375 30.393 3 364.852 28.782 4 365.603 26.806 5 367.671 26.364 6 369.164 27.860 7 368.719 29.926 8 368.242 31.537 9 367.765 33.149 1 3 411 412 413 AAG Crystallography ? ? Angstroms 1 A P -53.586 82.046 43.115 O3' -49.806 86.454 42.217 2 A P -48.813 87.678 41.827 O3' -43.249 87.275 39.928 3 G P -42.310 86.347 39.004 O3' -43.048 80.348 37.612 SG1 1 3 1 426.092 550.000 2 426.092 550.000 3 426.092 550.000 1 9 307 308 309 310 311 312 313 314 315 GUCU AAGAC LOOP1 4 6 LOOP2 4 6 LOOP3 4 6 LOOP4 4 6 LOOP5 4 6 LOOP6 4 6 LOOP7 4 6 LOOP8 4 6 LOOP9 4 6 LOOP10 4 6 LOOP11 4 6 LOOP12 4 6 LOOP13 4 6 LOOP14 4 6 LOOP15 4 6 LOOP16 4 6 LOOP17 4 6 LOOP18 4 6 LOOP19 4 6 LOOP20 4 6 LOOP21 4 6 LOOP22 4 6 LOOP23 4 6 LOOP24 4 6 LOOP25 4 6 LOOP26 4 6 LOOP27 4 6 LOOP28 4 6 LOOP29 4 6 LOOP30 4 6 LOOP31 4 6 LOOP32 4 6 LOOP33 4 6 LOOP34 4 6 LOOP35 4 6 LOOP36 4 6 LOOP37 4 6 LOOP38 4 6 LOOP39 4 6 LOOP40 4 6 LOOP41 4 6 LOOP42 4 6 LOOP43 4 6 LOOP44 4 6 LOOP45 4 6 LOOP46 4 6 LOOP47 4 6 LOOP48 4 6 LOOP49 4 6 LOOP50 4 6 LOOP51 4 6 LOOP52 4 6 LOOP53 4 6 LOOP54 4 6 LOOP55 4 6 LOOP56 4 6 LOOP57 4 6 LOOP58 4 6 LOOP59 4 6 LOOP60 4 6 Crystallography ? ? Angstroms 1 G P -29.514 89.302 52.902 O3' -33.937 87.252 51.355 2 U P -34.868 87.199 52.660 O3' -38.799 83.785 53.080 3 C P -39.532 84.098 54.467 O3' -41.720 80.385 57.353 4 U P -42.334 80.825 58.777 O3' -39.615 77.273 62.535 5 A P -39.955 77.725 64.045 O3' -34.937 79.547 66.303 6 A P -34.778 78.945 67.775 O3' -29.544 77.264 69.028 7 G P -29.559 75.681 68.824 O3' -29.538 72.982 64.302 8 A P -28.829 72.632 62.891 O3' -31.356 71.749 57.712 9 C P -29.935 71.593 56.994 O3' -30.330 71.874 51.838 1 9 + + c 2 8 - - c 3 7 + + c 4 5 ! ! ! 1 9 3 SG1 4 6 1 372.589 75.618 2 374.022 74.740 3 375.454 73.862 4 377.335 72.896 5 379.167 73.951 6 379.275 76.062 7 377.561 77.300 8 376.129 78.178 9 374.696 79.056 1 3 411 412 413 AAG Crystallography ? ? Angstroms 1 A P -17.752 57.317 88.665 O3' -19.334 62.486 86.364 2 A P -19.910 63.855 85.707 O3' -19.594 65.491 80.054 3 G P -19.655 64.867 78.571 O3' -18.325 59.073 76.800 SG1 1 3 1 426.092 550.000 2 426.092 550.000 3 426.092 550.000 1 9 307 308 309 310 311 312 313 314 315 GU CUAAGAC LOOP1 4 6 LOOP2 4 6 LOOP3 4 6 LOOP4 4 6 LOOP5 4 6 LOOP6 4 6 LOOP7 4 6 LOOP8 4 6 LOOP9 4 6 LOOP10 4 6 LOOP11 4 6 LOOP12 4 6 LOOP13 4 6 LOOP14 4 6 LOOP15 4 6 LOOP16 4 6 LOOP17 4 6 LOOP18 4 6 LOOP19 4 6 LOOP20 4 6 LOOP21 4 6 LOOP22 4 6 LOOP23 4 6 LOOP24 4 6 LOOP25 4 6 LOOP26 4 6 LOOP27 4 6 LOOP28 4 6 LOOP29 4 6 LOOP30 4 6 LOOP31 4 6 LOOP32 4 6 LOOP33 4 6 LOOP34 4 6 LOOP35 4 6 LOOP36 4 6 LOOP37 4 6 LOOP38 4 6 LOOP39 4 6 LOOP40 4 6 LOOP41 4 6 LOOP42 4 6 LOOP43 4 6 LOOP44 4 6 LOOP45 4 6 LOOP46 4 6 LOOP47 4 6 LOOP48 4 6 LOOP49 4 6 LOOP50 4 6 LOOP51 4 6 LOOP52 4 6 LOOP53 4 6 LOOP54 4 6 LOOP55 4 6 LOOP56 4 6 LOOP57 4 6 LOOP58 4 6 LOOP59 4 6 LOOP60 4 6 Crystallography ? ? Angstroms 1 G P -5.425 77.190 75.211 O3' -7.154 73.008 77.593 2 U P -6.328 72.918 78.964 O3' -5.643 68.379 81.456 3 C P -4.852 68.713 82.807 O3' -1.431 65.427 84.905 4 U P -0.630 65.932 86.210 O3' 4.964 65.262 84.661 5 A P 5.914 65.926 85.781 O3' 8.526 70.392 83.167 6 A P 10.079 70.382 83.546 O3' 13.507 71.704 79.269 7 G P 14.050 70.304 78.728 O3' 11.502 66.730 75.819 8 A P 10.698 66.348 74.467 O3' 5.991 62.956 73.908 9 C P 5.901 63.262 72.341 O3' 1.341 61.824 70.348 1 9 + + c 2 8 - - c 3 7 + + c 4 5 ! ! ! 1 9 3 SG1 4 6 1 292.773 76.814 2 294.282 76.076 3 295.792 75.339 4 297.756 74.558 5 299.479 75.783 6 299.386 77.895 7 297.562 78.963 8 296.052 79.700 9 294.542 80.437 1 3 411 412 413 AAG Crystallography ? ? Angstroms 1 A P 42.615 65.936 72.790 O3' 37.857 68.907 74.537 2 A P 36.509 69.609 75.108 O3' 31.139 69.493 72.683 3 G P 30.163 68.510 71.861 O3' 31.723 63.719 68.245 SG1 1 3 1 426.092 550.000 2 426.092 550.000 3 426.092 550.000 1 9 307 308 309 310 311 312 313 314 315 GUCUAAGAC LOOP1 4 6 LOOP2 4 6 LOOP3 4 6 LOOP4 4 6 LOOP5 4 6 LOOP6 4 6 LOOP7 4 6 LOOP8 4 6 LOOP9 4 6 LOOP10 4 6 LOOP11 4 6 LOOP12 4 6 LOOP13 4 6 LOOP14 4 6 LOOP15 4 6 LOOP16 4 6 LOOP17 4 6 LOOP18 4 6 LOOP19 4 6 LOOP20 4 6 LOOP21 4 6 LOOP22 4 6 LOOP23 4 6 LOOP24 4 6 LOOP25 4 6 LOOP26 4 6 LOOP27 4 6 LOOP28 4 6 LOOP29 4 6 LOOP30 4 6 LOOP31 4 6 LOOP32 4 6 LOOP33 4 6 LOOP34 4 6 LOOP35 4 6 LOOP36 4 6 LOOP37 4 6 LOOP38 4 6 LOOP39 4 6 LOOP40 4 6 LOOP41 4 6 LOOP42 4 6 LOOP43 4 6 LOOP44 4 6 LOOP45 4 6 LOOP46 4 6 LOOP47 4 6 LOOP48 4 6 LOOP49 4 6 LOOP50 4 6 LOOP51 4 6 LOOP52 4 6 LOOP53 4 6 LOOP54 4 6 LOOP55 4 6 LOOP56 4 6 LOOP57 4 6 LOOP58 4 6 LOOP59 4 6 LOOP60 4 6 Crystallography ? ? Angstroms 1 G P 72.843 78.998 -9.879 O3' 68.534 81.042 -11.725 2 U P 68.367 82.449 -10.977 O3' 63.695 84.718 -10.419 3 C P 63.953 86.127 -9.706 O3' 60.554 88.227 -6.398 4 U P 60.984 89.601 -5.673 O3' 60.402 88.333 0.002 5 A P 61.003 89.540 0.885 O3' 65.609 87.332 3.626 6 A P 65.578 87.796 5.155 O3' 67.138 83.799 8.814 7 G P 65.771 83.212 9.390 O3' 62.365 79.968 7.021 8 A P 62.060 78.554 6.296 O3' 58.705 77.543 1.639 9 C P 59.098 75.992 1.634 O3' 57.776 73.669 -2.802 1 9 + + c 2 8 - - c 3 7 + + c 4 5 ! ! ! 1 9 3 SG1 4 6 1 143.434 23.489 2 143.311 21.813 3 143.189 20.138 4 143.194 18.024 5 144.972 16.880 6 146.897 17.752 7 147.210 19.843 8 147.333 21.519 9 147.456 23.194 1 3 411 412 413 A AG Crystallography ? ? Angstroms 1 A P 61.742 78.652 38.257 O3' 64.611 80.294 33.399 2 A P 65.280 80.826 32.019 O3' 65.301 78.100 26.795 3 G P 64.365 77.171 25.869 O3' 59.784 73.385 27.645 SG1 1 3 1 426.092 550.000 2 426.092 550.000 3 426.092 550.000 1 9 307 308 309 310 311 312 313 314 315 GUCUAAGA C LOOP1 4 6 LOOP2 4 6 LOOP3 4 6 LOOP4 4 6 LOOP5 4 6 LOOP6 4 6 LOOP7 4 6 LOOP8 4 6 LOOP9 4 6 LOOP10 4 6 LOOP11 4 6 LOOP12 4 6 LOOP13 4 6 LOOP14 4 6 LOOP15 4 6 LOOP16 4 6 LOOP17 4 6 LOOP18 4 6 LOOP19 4 6 LOOP20 4 6 LOOP21 4 6 LOOP22 4 6 LOOP23 4 6 LOOP24 4 6 LOOP25 4 6 LOOP26 4 6 LOOP27 4 6 LOOP28 4 6 LOOP29 4 6 LOOP30 4 6 LOOP31 4 6 LOOP32 4 6 LOOP33 4 6 LOOP34 4 6 LOOP35 4 6 LOOP36 4 6 LOOP37 4 6 LOOP38 4 6 LOOP39 4 6 LOOP40 4 6 LOOP41 4 6 LOOP42 4 6 LOOP43 4 6 LOOP44 4 6 LOOP45 4 6 LOOP46 4 6 LOOP47 4 6 LOOP48 4 6 LOOP49 4 6 LOOP50 4 6 LOOP51 4 6 LOOP52 4 6 LOOP53 4 6 LOOP54 4 6 LOOP55 4 6 LOOP56 4 6 LOOP57 4 6 LOOP58 4 6 LOOP59 4 6 LOOP60 4 6 Crystallography ? ? Angstroms 1 G P 80.764 67.978 22.378 O3' 77.075 69.303 25.663 2 U P 77.775 69.346 27.105 O3' 75.028 68.710 31.502 3 C P 76.054 68.902 32.714 O3' 75.606 66.286 37.170 4 U P 76.765 66.499 38.270 O3' 78.602 61.051 39.315 5 A P 79.920 61.098 40.242 O3' 84.223 59.041 36.949 6 A P 85.092 58.010 37.808 O3' 86.771 53.452 34.944 7 G P 85.745 52.303 35.361 O3' 80.756 51.671 33.797 8 A P 79.684 51.473 32.601 O3' 74.385 53.845 32.084 9 C P 74.179 53.185 30.643 O3' 70.189 55.290 28.097 1 9 + + c 2 8 - - c 3 7 + + c 4 5 ! ! ! 1 9 3 SG1 4 6 1 101.672 60.045 2 101.536 58.370 3 101.400 56.695 4 101.389 54.582 5 103.157 53.424 6 105.090 54.281 7 105.420 56.369 8 105.556 58.044 9 105.692 59.718 1 3 411 412 413 AAG Crystallography ? ? Angstroms 1 A P 94.860 25.234 42.739 O3' 95.393 30.840 41.063 2 A P 95.449 32.425 40.716 O3' 92.030 35.352 36.912 3 G P 90.514 35.385 36.367 O3' 86.389 30.754 36.261 SG1 1 3 1 426.092 550.000 2 426.092 550.000 3 426.092 550.000 1 9 307 308 309 310 311 312 313 314 315 GUCUAA GAC LOOP1 4 6 LOOP2 4 6 LOOP3 4 6 LOOP4 4 6 LOOP5 4 6 LOOP6 4 6 LOOP7 4 6 LOOP8 4 6 LOOP9 4 6 LOOP10 4 6 LOOP11 4 6 LOOP12 4 6 LOOP13 4 6 LOOP14 4 6 LOOP15 4 6 LOOP16 4 6 LOOP17 4 6 LOOP18 4 6 LOOP19 4 6 LOOP20 4 6 LOOP21 4 6 LOOP22 4 6 LOOP23 4 6 LOOP24 4 6 LOOP25 4 6 LOOP26 4 6 LOOP27 4 6 LOOP28 4 6 LOOP29 4 6 LOOP30 4 6 LOOP31 4 6 LOOP32 4 6 LOOP33 4 6 LOOP34 4 6 LOOP35 4 6 LOOP36 4 6 LOOP37 4 6 LOOP38 4 6 LOOP39 4 6 LOOP40 4 6 LOOP41 4 6 LOOP42 4 6 LOOP43 4 6 LOOP44 4 6 LOOP45 4 6 LOOP46 4 6 LOOP47 4 6 LOOP48 4 6 LOOP49 4 6 LOOP50 4 6 LOOP51 4 6 LOOP52 4 6 LOOP53 4 6 LOOP54 4 6 LOOP55 4 6 LOOP56 4 6 LOOP57 4 6 LOOP58 4 6 LOOP59 4 6 LOOP60 4 6 Crystallography ? ? Angstroms 1 G P 99.004 38.254 19.475 O3' 98.049 35.188 23.456 2 U P 99.325 34.224 23.576 O3' 99.007 29.532 25.849 3 C P 100.486 28.921 25.847 O3' 101.390 23.837 25.370 4 U P 102.929 23.367 25.281 O3' 103.085 20.304 20.308 5 A P 104.614 19.938 19.951 O3' 105.816 22.817 15.065 6 A P 106.586 21.841 14.060 O3'