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| Title: | | HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 REVERSE TRANSCRIPTASE COMPLEXED WITH A 33-BASE NUCLEOTIDE RNA PSEUDOKNOT | |
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| Molecular Description: |
HIV-1 REVERSE TRANSCRIPTASE/RNA PSEUDOKNOT COMPLEX |
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| Structural Features: | SINGLE STRAND, LOOPS, FLIPPED-OUT BASES, OVERHANGING BASES |
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| Nucleic Acid Sequence: |
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| Chains | C,F,I,L: | | A G A U U C C G U U U U C A G U C G G G A A A A A C U G A A |
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| Protein Sequence: |
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| Primary Citation: | Jaeger, J., Restle, T., Steitz, T.A.
The structure of HIV-1 reverse transcriptase complexed with an RNA pseudoknot inhibitor.
EMBO J.
, 17,
pp. 4535 - 4542, 1998.
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| Experimental Information: | X-RAY DIFFRACTION |
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| Space Group: |
C
1
2
1
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| Cell Constants: |
| a = 166.700 | b = 169.200 | c = 331.400 | (Ångstroms) |
 = 90.00 |  = 104.50 |  = 90.00 | (degrees) |
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| Refinement: | The structure was refined using the X-PLOR 3.853 program.
The R value is
34.0
for 32343 reflections
in the resolution range 30.0 to
4.75 Ångstroms
with Fobs > 1.1 sigma(Fobs).
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