1 76 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 GCGGAUUUAg CUCAGuuGGG AGAGCgCCAG AcUgAAgAPc UGGAGgUCcU GUGuPCGaUC CACAGAAUUC GCACCA 10 2MG 16 H2U 17 H2U 26 M2G 32 OMC 34 OMG 37 YYG 39 PSU 40 5MC 46 7MG 49 5MC 54 5MU 55 PSU 58 1MA LOOP1 54 60 LOOP2 14 21 LOOP3 33 37 Crystallography ? ? Angstroms 1 G P 97.321 -32.139 -1.486 O3' 93.630 -32.410 -5.228 2 C P 93.892 -33.943 -5.572 O3' 93.395 -34.737 -10.409 3 G P 93.701 -36.305 -10.484 O3' 96.198 -38.787 -13.458 4 G P 96.924 -40.029 -14.188 O3' 100.639 -42.287 -16.285 5 A P 101.341 -43.713 -16.051 O3' 106.526 -45.781 -15.483 6 U P 105.773 -47.080 -14.922 O3' 109.482 -49.048 -11.995 7 U P 108.771 -50.416 -11.556 O3' 110.379 -51.690 -6.033 8 U P 111.799 -52.437 -6.070 O3' 111.870 -57.239 -5.334 9 A P 113.435 -57.269 -4.960 O3' 117.061 -60.018 -2.195 10 g P 116.795 -59.532 -0.686 O3' 119.354 -55.319 -0.749 11 C P 118.692 -54.597 -2.024 O3' 120.915 -51.548 -5.805 12 U P 119.519 -51.011 -6.355 O3' 119.564 -49.955 -10.952 13 C P 118.163 -49.601 -11.633 O3' 115.562 -52.135 -15.893 14 A P 114.179 -52.311 -16.673 O3' 111.898 -56.551 -19.782 15 G P 110.365 -56.119 -19.973 O3' 107.466 -59.833 -20.714 16 u P 106.279 -58.902 -21.264 O3' 101.514 -60.734 -19.832 17 u P 101.255 -62.310 -19.774 O3' 96.342 -60.168 -18.022 18 G P 95.048 -60.491 -17.142 O3' 97.028 -65.112 -14.327 19 G P 98.451 -65.711 -14.766 O3' 100.037 -70.395 -12.399 20 G P 101.618 -70.175 -12.414 O3' 104.817 -67.293 -10.113 21 A P 105.972 -68.351 -9.726 O3' 110.058 -67.134 -13.106 22 G P 110.884 -68.492 -12.839 O3' 115.990 -67.096 -13.338 23 A P 117.065 -67.593 -14.432 O3' 121.602 -65.079 -15.922 24 G P 123.069 -65.032 -15.245 O3' 126.787 -62.338 -14.490 25 C P 127.499 -62.973 -13.196 O3' 129.991 -60.193 -9.607 26 g P 130.339 -61.390 -8.598 O3' 129.485 -61.529 -3.556 27 C P 130.601 -62.637 -3.853 O3' 129.270 -66.487 0.223 28 C P 130.637 -67.311 0.209 O3' 129.089 -72.678 0.813 29 A P 130.591 -73.244 0.926 O3' 131.861 -78.040 -1.094 30 G P 133.416 -77.979 -1.450 O3' 135.086 -80.544 -4.482 31 A P 136.424 -79.663 -4.327 O3' 138.977 -80.342 -8.690 32 c O3' 143.860 -77.153 -10.519 P 140.448 -79.879 -8.268 33 U P 144.819 -77.263 -9.267 O3' 147.724 -73.182 -8.108 34 g P 148.706 -74.082 -7.214 O3' 145.741 -73.007 -2.951 35 A P 144.577 -73.154 -4.039 O3' 141.531 -69.201 -3.173 36 A P 140.290 -68.577 -3.988 O3' 138.694 -64.578 -5.625 37 g P 137.616 -64.830 -6.782 O3' 136.408 -62.650 -10.734 38 A P 135.380 -63.545 -11.557 O3' 135.087 -65.441 -16.660 39 P O3' 133.005 -70.135 -18.544 P 133.595 -65.917 -16.384 40 c P 131.562 -70.724 -18.136 O3' 130.039 -75.314 -17.460 41 U P 128.572 -75.337 -16.794 O3' 126.008 -78.226 -14.828 42 G P 124.475 -77.854 -14.513 O3' 121.458 -77.698 -9.639 43 G P 120.279 -76.672 -9.277 O3' 118.861 -75.517 -4.750 44 A P 117.758 -74.442 -5.223 O3' 116.726 -71.774 -0.713 45 G P 115.441 -70.834 -0.925 O3' 114.702 -66.257 0.400 46 g P 113.142 -66.301 0.042 O3' 109.764 -61.190 -0.868 47 U P 110.082 -60.235 0.384 O3' 105.469 -61.040 -1.923 48 C P 104.470 -60.822 -3.166 O3' 106.642 -56.505 -6.255 49 c P 106.139 -54.983 -6.066 O3' 104.866 -55.203 -1.063 50 U P 103.425 -55.894 -1.154 O3' 99.387 -54.951 1.954 51 G P 98.196 -55.910 1.488 O3' 93.437 -54.827 3.036 52 U P 92.488 -56.034 2.543 O3' 87.763 -55.303 0.061 53 G P 87.119 -56.431 -0.871 O3' 83.974 -55.875 -4.794 54 u O3' 83.250 -59.676 -9.617 P 83.539 -57.397 -4.956 55 P O3' 84.573 -65.371 -10.325 P 82.500 -60.956 -8.972 56 C P 83.698 -66.295 -9.321 O3' 86.722 -67.484 -5.724 57 G P 87.563 -66.167 -5.415 O3' 92.872 -65.422 -5.076 58 a P 92.794 -63.846 -4.864 O3' 97.765 -61.145 -6.546 59 U P 98.958 -61.993 -5.879 O3' 99.965 -57.636 -8.229 60 C P 98.471 -57.403 -8.777 O3' 98.689 -55.687 -14.125 61 C P 98.316 -54.146 -14.317 O3' 93.899 -52.177 -15.626 62 A P 94.158 -50.735 -14.980 O3' 90.238 -48.388 -12.975 63 C P 90.978 -47.005 -12.625 O3' 89.229 -45.126 -8.393 64 A P 89.895 -43.931 -7.592 O3' 92.414 -42.842 -2.726 65 G P 93.692 -41.927 -2.398 O3' 98.091 -41.835 0.802 66 A P 99.222 -40.813 0.349 O3' 103.889 -41.519 2.060 67 A P 104.501 -40.121 1.561 O3' 109.025 -40.232 0.255 68 U P 109.658 -39.157 -0.757 O3' 113.013 -38.658 -5.074 69 U P 112.990 -37.071 -5.308 O3' 112.405 -35.709 -10.637 70 C P 112.175 -34.210 -10.147 O3' 110.312 -32.556 -14.762 71 G P 109.791 -31.051 -14.640 O3' 105.445 -28.564 -17.076 72 C P 105.421 -27.170 -16.318 O3' 100.483 -25.571 -16.519 73 A P 100.340 -24.124 -15.858 O3' 96.281 -22.320 -12.444 74 C P 96.705 -20.791 -12.212 O3' 94.384 -19.703 -7.699 75 C P 94.601 -18.133 -7.557 O3' 98.031 -15.202 -3.551 76 A P 97.147 -14.283 -2.585 O3' 95.094 -15.341 2.265 9 syn 16 syn 17 syn 19 syn 20 syn 1 72 + + c 2 71 + + c 3 70 + + c 4 69 W W c 5 68 - - c 6 67 - - c 7 66 - - c 8 14 W H t 9 23 H H t 10 25 + + c 11 24 + + c 12 23 W W c 13 22 + + c 15 48 W W t 16 59 W W t 18 55 W S t 19 56 + + c 22 46 H W t 26 44 W W c 27 43 + + c 28 42 + + c 29 41 - - c 30 40 + + c 31 39 W H c 49 65 + + c 50 64 - - c 51 63 + + c 52 62 - - c 53 61 + + c 54 58 W H t 20 57 ! ! ! 32 38 ! ! ! 8 21 ! ! ! 8 15 ! ! ! 33 35 ! ! ! 33 36 ! ! ! 47 50 ! ! ! 58 60 ! ! ! 1 72 7 49 65 5 10 25 4 26 44 7 SG1 8 9 SG2 14 21 SG3 33 37 SG4 45 48 SG5 54 60 SG6 73 76 1 481.262 56.885 2 481.262 80.587 3 481.262 104.289 4 481.262 127.991 5 481.262 151.693 6 481.262 175.396 7 481.262 199.098 8 467.041 199.098 9 452.820 199.098 10 247.566 366.199 11 271.242 365.085 12 294.918 363.972 13 318.594 362.858 14 338.846 375.476 15 362.705 375.797 16 383.289 363.728 17 394.661 342.750 18 393.540 318.915 19 380.250 299.098 20 358.624 289.014 21 334.900 291.573 22 315.921 306.036 23 292.245 307.149 24 268.569 308.263 25 244.893 309.376 26 197.542 311.603 27 173.866 312.717 28 150.190 313.830 29 126.514 314.944 30 102.838 316.057 31 79.162 317.171 32 55.486 318.284 33 30.497 312.500 34 8.119 325.037 35 0.000 349.368 36 10.366 372.830 37 33.822 383.211 38 58.158 375.107 39 81.834 373.993 40 105.510 372.880 41 129.186 371.766 42 152.862 370.653 43 176.538 369.539 44 200.214 368.426 45 424.377 246.502 46 438.598 246.502 47 452.820 246.502 48 467.041 246.502 49 481.262 246.502 50 481.262 270.204 51 481.262 293.906 52 481.262 317.608 53 481.262 341.310 54 469.409 362.391 55 471.413 386.492 56 486.583 405.326 57 509.705 412.417 58 532.826 405.326 59 547.997 386.492 60 550.000 362.391 61 538.147 341.310 62 538.147 317.608 63 538.147 293.906 64 538.147 270.204 65 538.147 246.502 66 538.147 199.098 67 538.147 175.396 68 538.147 151.693 69 538.147 127.991 70 538.147 104.289 71 538.147 80.587 72 538.147 56.885 73 538.147 42.664 74 538.147 28.443 75 538.147 14.221 76 538.147 0.000