1 58 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 GCCAGGAUGU AGGCUUAGAA GCAGCCAUCA UUUAAAGAAA GCGUAAUAGC UCACUGGU LOOP1 44 47 LOOP2 16 22 Crystallography ? ? Angstroms 1 G P 75.154 8.066 176.985 O3' 74.042 12.381 180.262 2 C P 75.359 12.324 181.185 O3' 74.380 12.521 186.359 3 C P 75.639 11.923 187.172 O3' 75.928 9.849 191.642 4 A P 77.526 9.797 191.526 O3' 79.199 6.043 194.019 5 G P 80.726 5.884 193.814 O3' 83.373 1.087 193.624 6 G P 84.928 1.393 193.268 O3' 88.402 -0.621 189.633 7 A P 89.556 0.184 190.385 O3' 90.618 -2.053 195.062 8 U P 92.190 -1.931 195.115 O3' 94.886 -5.817 197.600 9 G P 96.310 -5.440 197.038 O3' 100.240 -8.713 197.409 10 U P 101.519 -8.062 196.818 O3' 99.745 -3.204 193.986 11 A P 100.378 -1.941 194.697 O3' 103.573 -2.390 190.169 12 G P 102.775 -3.065 188.985 O3' 105.337 -7.231 190.292 13 G P 106.881 -6.911 190.185 O3' 111.168 -9.280 187.893 14 C P 112.232 -8.274 188.535 O3' 115.580 -7.188 184.869 15 U P 116.636 -6.240 185.576 O3' 118.148 -2.389 182.549 16 U P 118.931 -1.047 182.892 O3' 118.251 4.253 183.562 17 A P 119.584 4.544 184.380 O3' 117.576 5.030 189.008 18 G P 116.473 3.909 188.878 O3' 111.492 4.503 190.049 19 A P 110.889 3.065 189.730 O3' 107.496 1.312 185.729 20 A P 106.617 0.134 186.251 O3' 100.912 2.345 187.698 21 G P 100.006 1.358 188.550 O3' 101.352 -0.034 184.231 22 C P 102.407 0.911 183.475 O3' 102.802 4.414 179.610 23 A P 104.210 4.773 180.254 O3' 106.426 4.880 175.484 24 G P 106.094 3.499 174.830 O3' 108.773 -0.571 173.216 25 C P 108.667 -2.105 173.296 O3' 110.172 -6.461 173.220 26 C P 109.116 -7.642 173.053 O3' 107.640 -12.263 175.938 27 A P 106.459 -12.595 174.966 O3' 102.489 -14.509 178.208 28 U P 101.007 -14.902 177.759 O3' 96.988 -13.701 180.692 29 C P 96.589 -15.094 179.992 O3' 95.538 -17.624 184.937 30 A P 93.954 -17.783 184.918 O3' 92.574 -18.158 189.881 31 U P 91.128 -17.911 190.387 O3' 90.037 -15.660 195.218 32 U P 88.640 -16.371 195.386 O3' 84.594 -13.597 197.157 33 U P 83.125 -13.923 196.660 O3' 79.392 -10.931 193.412 34 A P 78.118 -11.775 192.978 O3' 78.115 -10.762 188.078 35 A P 79.563 -11.299 187.969 O3' 82.512 -7.940 185.057 36 A P 83.834 -8.829 184.860 O3' 88.075 -6.233 184.764 37 G P 89.411 -7.013 185.256 O3' 93.198 -8.142 181.745 38 A P 93.566 -9.255 182.806 O3' 97.194 -4.946 182.651 39 A P 98.025 -3.984 181.736 O3' 94.565 -0.912 178.435 40 A P 94.636 -1.572 176.964 O3' 94.476 2.576 174.115 41 G P 95.533 3.725 174.306 O3' 95.611 9.225 174.967 42 C P 96.803 10.093 175.595 O3' 96.521 14.481 177.787 43 G P 98.054 14.740 178.251 O3' 99.379 16.340 183.015 44 U P 100.900 16.495 182.654 O3' 104.359 16.007 186.074 45 A P 105.378 16.496 184.932 O3' 108.028 11.775 184.886 46 A P 106.664 11.075 184.549 O3' 106.150 6.718 187.730 47 U P 104.648 6.315 187.601 O3' 100.943 6.527 191.612 48 A P 99.419 6.425 191.129 O3' 95.880 8.842 193.991 49 G P 94.365 8.766 193.509 O3' 90.615 11.582 191.668 50 C P 89.458 10.670 191.056 O3' 87.187 11.992 187.025 51 U P 86.400 10.714 186.829 O3' 84.328 8.634 182.169 52 C P 83.648 7.260 182.281 O3' 83.503 3.953 178.390 53 A P 82.541 2.916 178.953 O3' 83.514 -2.345 177.438 54 C P 82.088 -2.891 177.620 O3' 79.791 -6.201 180.936 55 U P 78.454 -5.428 181.141 O3' 75.546 -6.229 185.287 56 G P 74.116 -5.743 184.866 O3' 70.882 -4.172 188.486 57 G P 69.645 -3.662 187.662 O3' 66.714 0.271 189.613 58 U P 65.585 0.114 188.560 O3' 63.027 4.148 187.182 19 syn 36 syn 38 syn 1 58 W W c 2 57 + + c 3 56 + + c 4 55 - - c 5 35 S S t 5 54 + + c 6 53 S H t 7 31 - - c 8 30 - - c 9 29 + + c 10 38 W H c 12 26 + + c 13 25 + + c 14 24 + + c 21 41 W H c 22 42 W H c 32 36 W W t 37 52 + + c 39 40 S H c 40 51 - - c 41 50 + + c 42 49 + + c 43 48 S H t 6 54 ! ! ! 15 23 ! ! ! 21 50 ! ! ! 22 49 ! ! ! 15 19 ! ! ! 28 38 ! ! ! 33 35 ! ! ! 34 55 ! ! ! 6 36 ! ! ! 7 37 ! ! ! 16 19 ! ! ! 18 45 ! ! ! 18 46 ! ! ! 27 39 ! ! ! 28 29 ! ! ! 35 54 ! ! ! 38 39 ! ! ! 44 46 ! ! ! 44 47 ! ! ! 1 58 6 40 51 4 7 31 3 12 26 4 SG1 10 11 SG2 16 22 SG3 27 28 SG4 32 39 SG5 44 47 SG6 52 52 1 506.857 76.092 2 501.238 87.230 3 495.619 98.367 4 490.000 109.505 5 484.380 120.642 6 478.761 131.780 7 537.422 197.603 8 526.102 202.843 9 514.781 208.084 10 507.989 211.228 11 501.197 214.373 12 478.307 290.072 13 469.008 298.389 14 459.710 306.705 15 450.412 315.021 16 446.301 327.068 17 436.143 334.738 18 423.432 335.395 19 412.537 328.813 20 407.206 317.254 21 409.272 304.694 22 418.024 295.452 23 430.452 292.705 24 439.751 284.389 25 449.049 276.073 26 458.347 267.756 27 513.774 241.542 28 520.566 238.398 29 527.359 235.253 30 538.679 230.013 31 550.000 224.772 32 520.983 181.027 33 514.300 177.656 34 507.618 174.284 35 500.935 170.913 36 494.253 167.541 37 487.570 164.170 38 480.888 160.798 39 474.205 157.426 40 467.523 154.055 41 461.903 165.192 42 456.284 176.330 43 450.665 187.467 44 445.771 200.913 45 432.468 206.183 46 419.693 199.738 47 416.028 185.907 48 423.935 173.981 49 429.554 162.844 50 435.173 151.706 51 440.793 140.569 52 445.349 114.922 53 452.031 118.294 54 457.650 107.156 55 463.270 96.019 56 468.889 84.881 57 474.508 73.744 58 480.127 62.606 1 29 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 GG GUGCUCAGUA CGAGAGGAAC CGCACCC LOOP3 15 16 Crystallography ? ? Angstroms 1 G O3' 86.926 58.689 175.815 2 G P 88.483 59.018 176.132 O3' 91.807 62.296 173.535 3 G P 93.173 62.300 174.389 O3' 96.564 66.040 174.319 4 U P 97.580 65.210 175.255 O3' 100.375 68.257 178.262 5 G P 101.334 67.140 178.895 O3' 103.053 68.718 183.685 6 C P 103.997 67.498 184.185 O3' 102.960 65.872 189.369 7 U P 103.765 64.590 189.880 O3' 101.635 61.929 193.933 8 C P 102.703 60.768 194.212 O3' 100.584 56.511 195.568 9 A P 101.750 55.454 195.856 O3' 106.918 57.698 194.289 10 G P 107.755 58.922 194.927 O3' 109.823 54.066 194.399 11 U P 110.452 52.689 194.977 O3' 106.919 49.923 197.410 12 A P 107.207 48.342 197.180 O3' 104.644 44.483 195.393 13 C P 105.954 43.580 195.570 O3' 107.107 40.785 191.367 14 G P 108.337 39.921 191.933 O3' 112.440 38.980 189.400 15 A P 113.166 38.153 190.587 O3' 117.105 41.425 192.169 16 G P 116.628 42.925 191.907 O3' 120.027 46.168 188.992 17 A P 119.324 47.587 188.798 O3' 119.769 49.999 184.442 18 G P 118.944 51.310 184.848 O3' 113.763 51.300 182.535 19 G P 112.645 52.450 182.616 O3' 108.006 51.931 183.983 20 A P 107.423 53.407 184.154 O3' 102.322 52.285 183.839 21 A P 101.233 53.462 183.929 O3' 96.810 50.703 184.192 22 C P 95.812 51.947 184.166 O3' 91.552 51.887 187.074 23 C P 91.139 53.451 186.975 O3' 89.165 55.478 191.402 24 G P 88.747 56.861 190.713 O3' 89.113 61.644 192.910 25 C P 88.699 63.044 192.263 O3' 90.372 68.196 191.951 26 A P 89.335 68.845 190.924 O3' 91.069 73.364 188.960 27 C P 89.843 73.967 188.113 O3' 90.134 76.721 183.427 28 C P 88.710 76.643 182.728 O3' 88.268 76.229 177.837 29 C P 86.757 76.035 177.288 O3' 85.218 73.960 172.982 1 29 + + c 2 28 + + c 3 27 + + c 4 26 - - c 5 25 + + c 6 24 + + c 9 21 H H t 11 20 W H t 12 19 H S t 13 18 + + c 14 17 S H t 7 23 ! ! ! 8 23 ! ! ! 10 11 ! ! ! 11 21 ! ! ! 10 20 ! ! ! 1 29 7 11 20 4 SG1 8 10 SG2 15 16 SG3 21 22 1 0.000 0.000 2 0.000 12.475 3 0.000 24.950 4 0.000 37.424 5 0.000 49.899 6 0.000 62.374 7 0.000 74.849 8 0.000 87.323 9 0.000 112.273 10 0.000 137.223 11 0.000 149.697 12 0.000 162.172 13 0.000 174.647 14 0.000 187.122 15 5.879 204.326 16 24.060 204.326 17 29.939 187.122 18 29.939 174.647 19 29.939 162.172 20 29.939 149.697 21 29.939 124.748 22 29.939 99.798 23 29.939 74.849 24 29.939 62.374 25 29.939 49.899 26 29.939 37.424 27 29.939 24.950 28 29.939 12.475 29 29.939 0.000