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| Title: |  | STRUCTURE OF THE THERMUS THERMOPHILUS 30S RIBOSOMAL SUBUNIT IN COMPLEX WITH THE ANTIBIOTICS STREPTOMYCIN, SPECTINOMYCIN, AND PAROMOMYCIN |  |
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| Molecular Description: | INHIBITED 30S RIBOSOMAL SUBUNIT |
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| Structural Features: | SINGLE STRAND |
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| Nucleic Acid Sequence: |
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| Protein Sequence: |
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| Chains | B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, V | | Click here for sequences. |
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| Primary Citation: | Carter, A.P., Clemons Jr., W.M., Brodersen, D.E., Morgan-Warren, R.J., Wimberly, B.T., Ramakrishnan, V.
Functional insights from the structure of the 30S ribosomal subunit and its interactions with antibiotics
Nature
, 407,
pp. 340 - 348, 2000.
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| Experimental Information: | X-RAY DIFFRACTION |
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| Space Group: |
P
41
21
2
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| Cell Constants: |
| a = 402.001 | b = 402.001 | c = 176.489 | (Ångstroms) |
= 90.00 | = 90.00 | = 90.00 | (degrees) |
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| Refinement: | The structure was refined using the CNS program.
The R value is
22.1
for 259882 reflections
in the resolution range 95.346 to
3.000 Ångstroms
with I > 0.0 sigma(I).
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