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| Title: |  | THE CRYSTAL STRUCTURE OF THE 50S LARGE RIBOSOMAL SUBUNIT FROM DEINOCOCCUS RADIODURANS COMPLEXED WITH TELITHROMYCIN KETOLIDE ANTIBIOTIC |  |
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| Molecular Description: | 50S Large ribosomal subunit |
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| Structural Features: | SINGLE STRAND, LOOPS, BULGES, FLIPPED-OUT BASES, BASE TRIPLET |
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| Nucleic Acid Sequence: |
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| Primary Citation: | Berisio, R., Harms, J., Schluenzen, F., Zarivach, R., Hansen, H.A., Fucini, P., Yonath, A.
Structural insight into the antibiotic action of telithromycin against resistant mutants
J.Bacteriol.
, 185,
pp. 4276 - 4279, 2003.
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| Experimental Information: | X-RAY DIFFRACTION |
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| Space Group: |
I
2
2
2
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| Cell Constants: |
| a = 170.000 | b = 414.500 | c = 693.000 | (Ångstroms) |
= 90.00 | = 90.00 | = 90.00 | (degrees) |
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| Refinement: | The structure was refined using the CNS program.
The R value is
27.3
for 245223 reflections
in the resolution range 15.00 to
3.40 Ångstroms
with Fobs > 2.000 sigma(Fobs).
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