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| Title: |  | COMPLEX OF THE LARGE RIBOSOMAL SUBUNIT FROM DEINOCOCCUS RADIODURANS WITH QUINUPRISTIN AND DALFOPRISTIN |  |
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| Molecular Description: | 50S RIBOSOMAL PROTEIN L33 50S RIBOSOMAL PROTEIN L34 50S RIBOSOMAL PROTEIN L35 50S RIBOSOMAL PROTEIN L36 QUINUPRISTIN 50S RIBOSOMAL PROTEIN L2 50S RIBOSOMAL PROTEIN L4 50S RIBOSOMAL PROTEIN L5 50S RIBOSOMAL PROTEIN L6 50S RIBOSOMAL PROTEIN L9 50S RIBOSOMAL PROTEIN L11 50S RIBOSOMAL PROTEIN L13 50S RIBOSOMAL PROTEIN L14 50S RIBOSOMAL PROTEIN L15 50S RIBOSOMAL PROTEIN L16 50S RIBOSOMAL PROTEIN L17 50S RIBOSOMAL PROTEIN L18 50S RIBOSOMAL PROTEIN L19 50S RIBOSOMAL PROTEIN L20 50S RIBOSOMAL PROTEIN L21 50S RIBOSOMAL PROTEIN L22 50S RIBOSOMAL PROTEIN L23 50S RIBOSOMAL PROTEIN L24 GENERAL STRESS PROTEIN CTC 50S RIBOSOMAL PROTEIN L27 50S RIBOSOMAL PROTEIN L29 50S RIBOSOMAL PROTEIN L30 50S RIBOSOMAL PROTEIN L31 50S RIBOSOMAL PROTEIN L32/RNA Complex
5-(2-DIETHYLAMINO-ETHANESULFONYL)-21-HYDROXY-10-ISOPROPYL-11,19-DIMETHYL-9,26-DIOXA-3,15,28-TRIAZA-TRICYCLO[23.2.1.00,255]OCTACOSA-1(27),12,17,19,25(28)-PENTAENE-2,8,14,23-TETRAONE |
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| Structural Features: | SINGLE STRAND |
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| Nucleic Acid Sequence: |
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| Protein Sequence: |
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| Chains | 1, 2, 3, 4, 5, A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U, W, X, Y, Z | | Click here for sequences. |
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| Primary Citation: | Harms, J.M., Schlunzen, F., Fucini, P., Bartels, H., Yonath, A.
Alterations at the Peptidyl Transferase Centre of the Ribosome Induced by the Synergistic Action of the Streptogramins Dalfopristin and Quinupristin.
Bmc Biol.
, 2,
pp. 4, 2004.
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| Experimental Information: | X-RAY DIFFRACTION |
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| Space Group: |
I
2
2
2
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| Cell Constants: |
| a = 168.500 | b = 406.000 | c = 693.000 | (Ångstroms) |
= 90.00 | = 90.00 | = 90.00 | (degrees) |
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| Refinement: | The structure was refined using the CNS 1.0 program.
The R value is
27.8
for 266331 reflections
in the resolution range 15.00 to
3.42 Ångstroms
with Fobs > 0.000 sigma(Fobs).
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