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| Title: |  | INHIBITION OF PEPTIDE BOND FORMATION BY PLEUROMUTILINS: THE STRUCTURE OF THE 50S RIBOSOMAL SUBUNIT FROM DEINOCOCCUS RADIODURANS IN COMPLEX WITH TIAMULIN |  |
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| Molecular Description: | 50S RIBOSOME |
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| Structural Features: | SINGLE STRAND |
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| Nucleic Acid Sequence: |
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| Protein Sequence: |
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| Chains | 1, 2, 3, 4, A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U, W, X, Y, Z | | Click here for sequences. |
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| Primary Citation: | Schluenzen, F., Pyetan, E., Fucini, P., Yonath, A., Harms, J.M.
Inhibition of peptide bond formation by pleuromutilins: the structure of the 50S ribosomal subunit from Deinococcus radiodurans in complex with tiamulin.
Mol.Microbiol.
, 54,
pp. 1287 - 1294, 2004.
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| Experimental Information: | X-RAY DIFFRACTION |
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| Space Group: |
I
2
2
2
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| Cell Constants: |
| a = 168.700 | b = 405.000 | c = 693.000 | (Ångstroms) |
= 90.00 | = 90.00 | = 90.00 | (degrees) |
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| Refinement: | The structure was refined using the CNS 1.0 program.
The R value is
29.0
for 258817 reflections
in the resolution range 15.00 to
3.5 Ångstroms
with Fobs > 1.000 sigma(Fobs).
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