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| Title: | | CRYSTAL STRUCTURE OF THE MUTANT 50S RIBOSOMAL SUBUNIT OF HALOARCULA MARISMORTUI CONTAINING A THREE RESIDUE DELETION IN L22 | |
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| Molecular Description: | 50S Ribosomal Subunit |
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| Structural Features: | SINGLE STRAND |
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| Nucleic Acid Sequence: |
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| Protein Sequence: |
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| Chains | 1, 2, 3, A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U, V, W, X, Y, Z | | Click here for sequences. |
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| Primary Citation: | Tu, D., Blaha, G., Moore, P.B., Steitz, T.A.
Structures of MLSBK antibiotics bound to mutated large ribosomal subunits provide a structural explanation for resistance.
Cell(Cambridge,Mass.)
, 121,
pp. 257 - 270, 2005.
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| Experimental Information: | X-RAY DIFFRACTION |
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| Space Group: |
C
2
2
21
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| Cell Constants: |
| a = 213.076 | b = 300.750 | c = 575.478 | (Ångstroms) |
 = 90.00 |  = 90.00 |  = 90.00 | (degrees) |
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| Refinement: | The structure was refined using the CNS program.
The R value is
18.4
for 400720 reflections
in the resolution range 29.94 to
2.80 Ångstroms
with Fobs > 0.0 sigma(Fobs).
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