1 75 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 UCCGUGAUAG UUPAAuGGuC AGAAUGGGCG CPUGUCgCGU GCCAGAUcGG GGuPCAAUUC CCCGUCGCGG AGCCA 13 PSU 16 H2U 19 H2U 32 PSU 37 1MG 48 5MC 53 5MU 54 PSU LOOP1 53 59 LOOP2 15 20 LOOP3 33 37 Crystallography ? ? Angstroms 1 U P 36.589 3.124 -4.704 O3' 35.745 3.779 -8.621 2 C P 35.426 5.184 -9.298 O3' 35.164 6.852 -14.172 3 C P 33.609 6.950 -14.627 O3' 30.860 7.605 -18.448 4 G P 29.341 7.663 -17.889 O3' 26.039 6.333 -21.415 5 U P 24.479 6.070 -21.068 O3' 20.425 3.380 -21.008 6 G P 19.124 3.878 -20.229 O3' 15.269 0.648 -17.884 7 A P 14.445 1.905 -17.307 O3' 12.005 -0.273 -12.396 8 U P 10.968 -1.483 -12.653 O3' 6.105 -0.001 -10.878 9 A P 6.364 -1.438 -10.203 O3' 1.532 -2.871 -7.070 10 G P 2.634 -3.148 -5.909 O3' 5.392 -7.332 -6.937 11 U P 6.179 -6.961 -8.276 O3' 7.597 -9.784 -11.666 12 U P 8.212 -9.240 -13.044 O3' 8.536 -8.966 -17.695 13 P P 9.151 -7.727 -18.488 O3' 6.717 -3.998 -22.055 14 A P 7.074 -2.577 -22.678 O3' 4.690 2.039 -24.963 15 A P 6.226 2.440 -25.269 O3' 5.818 8.045 -25.514 16 u P 7.314 8.320 -26.021 O3' 9.543 13.933 -25.226 17 G P 9.850 14.551 -23.744 O3' 4.484 15.841 -21.573 18 G P 3.100 16.141 -22.346 O3' -2.368 15.718 -21.232 19 u P -3.634 15.457 -22.159 O3' -6.312 16.697 -17.359 20 C P -5.228 16.479 -16.146 O3' -3.932 11.218 -13.282 21 A P -2.695 10.171 -13.307 O3' -3.455 6.978 -16.416 22 G P -4.207 5.561 -16.401 O3' -5.739 2.386 -20.125 23 A P -6.535 1.274 -19.249 O3' -5.802 -4.176 -20.888 24 A P -6.957 -4.820 -19.981 O3' -5.822 -9.661 -19.870 25 U P -6.454 -10.482 -18.628 O3' -5.214 -13.915 -15.545 26 G P -6.201 -14.213 -14.297 O3' -6.498 -14.458 -9.211 27 G P -8.001 -14.187 -8.701 O3' -9.526 -11.602 -4.384 28 G P -11.004 -12.170 -4.693 O3' -14.435 -9.473 -2.622 29 C P -15.868 -10.069 -3.082 O3' -19.964 -7.562 -4.636 30 G P -21.258 -8.383 -5.161 O3' -25.034 -7.658 -9.537 31 C P -25.965 -8.909 -9.874 O3' -27.457 -9.037 -14.287 32 P P -28.524 -10.186 -13.936 O3' -28.944 -13.567 -17.439 33 U P -30.411 -13.931 -16.937 O3' -31.063 -18.590 -17.302 34 G P -32.490 -18.910 -16.659 O3' -31.624 -20.172 -11.599 35 U P -30.468 -19.058 -11.740 O3' -26.232 -20.374 -9.431 36 C P -24.651 -20.168 -9.331 O3' -20.073 -21.176 -9.943 37 g P -19.529 -19.991 -10.923 O3' -15.947 -20.934 -15.152 38 C P -15.643 -19.999 -16.442 O3' -14.411 -18.742 -19.630 39 G P -13.845 -17.314 -20.132 O3' -16.657 -13.160 -22.758 40 U P -15.330 -12.254 -22.857 O3' -17.128 -7.580 -21.999 41 G P -15.850 -6.703 -21.538 O3' -16.680 -2.345 -18.611 42 C P -15.363 -1.684 -17.948 O3' -15.301 1.338 -14.059 43 C P -14.153 1.867 -13.073 O3' -12.394 2.890 -8.834 44 A P -10.910 3.481 -8.844 O3' -7.126 2.563 -5.449 45 G P -6.167 3.591 -6.230 O3' -1.502 1.557 -5.711 46 A P -0.791 2.916 -6.144 O3' 4.719 3.760 -7.625 47 U P 4.757 5.326 -7.271 O3' 9.301 4.425 -11.049 48 c P 10.927 4.553 -10.999 O3' 11.418 4.367 -5.806 49 G P 10.920 5.853 -5.569 O3' 12.637 7.915 -1.986 50 G P 12.323 9.474 -2.109 O3' 15.385 14.257 -0.982 51 G P 14.343 15.433 -1.255 O3' 16.391 19.442 -3.214 52 G P 15.680 20.531 -4.158 O3' 17.271 23.440 -8.864 53 u P 15.904 24.292 -9.020 O3' 15.435 26.017 -13.586 54 P P 14.083 26.726 -13.054 O3' 10.584 27.331 -16.078 55 C P 9.818 28.264 -15.008 O3' 6.129 25.656 -12.988 56 A P 7.342 24.634 -12.703 O3' 5.601 20.075 -13.020 57 A P 6.525 18.834 -12.637 O3' 6.919 13.892 -14.368 58 U P 6.413 12.719 -13.392 O3' 10.934 10.199 -14.653 59 U P 11.470 11.731 -14.722 O3' 13.405 11.602 -20.348 60 C P 14.972 11.251 -20.074 O3' 18.838 13.941 -19.648 61 C P 19.972 13.350 -18.705 O3' 23.341 16.073 -15.396 62 C P 24.002 14.589 -15.251 O3' 26.317 14.067 -10.204 63 C P 26.882 12.565 -10.260 O3' 27.578 10.258 -6.084 64 G P 27.596 8.649 -6.396 O3' 26.429 4.604 -3.695 65 U P 26.456 3.031 -4.045 O3' 24.659 -1.072 -3.367 66 C P 25.293 -2.138 -4.418 O3' 23.367 -5.913 -7.021 67 G P 24.390 -6.507 -8.110 O3' 23.821 -8.689 -12.263 68 C P 24.695 -9.125 -13.526 O3' 25.279 -8.981 -18.208 69 G P 26.821 -9.451 -18.133 O3' 29.745 -8.180 -21.668 70 G P 31.356 -8.143 -21.669 O3' 35.394 -5.569 -23.416 71 A P 36.896 -5.542 -22.827 O3' 40.899 -2.869 -22.148 72 G P 42.025 -3.564 -21.217 O3' 45.105 -1.237 -17.825 73 C P 46.089 -2.394 -17.557 O3' 48.222 -3.151 -12.678 74 C P 49.140 -4.331 -12.952 O3' 49.299 -8.592 -9.937 75 A P 50.359 -9.449 -10.616 O3' 49.655 -14.701 -11.140 57 syn 1 71 - - c 2 70 + + c 3 69 + + c 4 68 + + c 5 67 W W c 6 66 + + c 7 65 - - c 8 14 W H t 9 23 H H t 10 25 W W c 10 45 H W c 11 24 - - c 12 23 - - c 13 22 W W c 14 21 W S c 15 47 W W t 22 46 H W t 26 44 W W c 27 43 + + c 28 42 + + c 29 41 + + c 30 40 W W c 31 39 + + c 48 64 + + c 49 63 + + c 50 62 + + c 51 61 + + c 52 60 + + c 53 57 W H t 17 54 ! ! ! 32 38 ! ! ! 8 21 ! ! ! 8 46 ! ! ! 16 17 ! ! ! 19 20 ! ! ! 33 35 ! ! ! 1 71 7 48 64 5 10 25 5 26 44 7 SG1 8 9 SG2 15 20 SG3 33 37 SG4 45 47 SG5 53 59 SG6 72 75 1 62.341 13.526 2 84.926 16.916 3 107.511 20.307 4 130.096 23.698 5 152.680 27.089 6 175.265 30.480 7 197.850 33.871 8 199.884 20.320 9 201.919 6.769 10 310.525 312.486 11 310.525 289.648 12 310.525 266.810 13 310.525 243.972 14 310.525 221.134 15 319.887 199.219 16 313.889 176.155 17 295.035 161.578 18 271.204 161.578 19 252.351 176.155 20 246.352 199.219 21 255.714 221.134 22 255.714 243.972 23 255.714 266.810 24 255.714 289.648 25 255.714 312.486 26 255.714 358.162 27 255.714 381.000 28 255.714 403.838 29 255.714 426.675 30 255.714 449.513 31 255.714 472.351 32 255.714 495.189 33 249.016 518.979 34 260.069 541.085 35 283.120 550.000 36 306.170 541.085 37 317.223 518.979 38 310.525 495.189 39 310.525 472.351 40 310.525 449.513 41 310.525 426.675 42 310.525 403.838 43 310.525 381.000 44 310.525 358.162 45 249.123 0.000 46 247.089 13.551 47 245.054 27.102 48 243.019 40.653 49 265.604 44.043 50 288.189 47.434 51 310.774 50.825 52 333.358 54.216 53 355.141 45.938 54 377.819 51.295 55 393.595 68.445 56 397.044 91.490 57 386.979 112.507 58 366.863 124.268 59 343.611 122.729 60 325.220 108.419 61 302.636 105.029 62 280.051 101.638 63 257.466 98.247 64 234.881 94.856 65 189.712 88.074 66 167.127 84.683 67 144.542 81.292 68 121.958 77.902 69 99.373 74.511 70 76.788 71.120 71 54.203 67.729 72 40.653 65.695 73 27.102 63.660 74 13.551 61.625 75 0.000 59.591