1 73 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 UCCGUGAUAG UUPAAuGGuC AGAAUGGGCG CPUGUCgCGU GCCAGAUcGG GGuPCAAUUC CCCGUCGCGG AGC 13 PSU 16 H2U 19 H2U 32 PSU 37 1MG 48 5MC 53 5MU 54 PSU LOOP1 53 59 LOOP2 14 21 LOOP3 32 38 Crystallography ? ? Angstroms 1 U P 35.608 2.846 -5.040 O3' 36.810 4.697 -7.883 2 C P 35.764 5.533 -8.782 O3' 35.868 7.431 -13.605 3 C P 34.376 7.729 -14.133 O3' 31.412 7.812 -18.558 4 G P 29.939 8.006 -17.922 O3' 26.310 6.233 -21.181 5 U P 24.892 6.434 -20.456 O3' 21.127 3.201 -20.637 6 G P 19.999 4.093 -19.928 O3' 16.522 0.907 -17.904 7 A P 15.392 1.778 -17.180 O3' 12.819 -0.882 -12.269 8 U P 11.440 -1.642 -12.542 O3' 6.550 0.013 -10.821 9 A P 6.836 -1.352 -10.008 O3' 2.056 -2.959 -7.007 10 G P 2.991 -3.182 -5.726 O3' 5.946 -7.083 -6.521 11 U P 6.839 -7.146 -7.823 O3' 8.360 -9.900 -11.317 12 U P 9.055 -9.146 -12.555 O3' 9.665 -9.245 -17.428 13 P O3' 7.542 -4.359 -22.012 P 10.134 -8.024 -18.365 14 A P 8.058 -2.964 -22.633 O3' 5.704 1.613 -25.018 15 A P 7.213 2.094 -25.329 O3' 6.510 7.828 -25.146 16 u P 7.750 7.721 -26.154 O3' 11.122 11.968 -25.705 17 G P 10.113 13.129 -26.190 O3' 6.510 14.613 -22.308 18 G P 5.123 14.281 -23.081 O3' -0.384 16.819 -22.589 19 u P -0.682 15.730 -21.444 O3' -4.789 16.600 -16.897 20 C P -4.748 15.089 -16.367 O3' -1.129 11.186 -14.881 21 A P -2.273 10.379 -14.071 O3' -2.771 6.064 -17.138 22 G P -3.730 4.945 -16.547 O3' -5.057 1.814 -20.539 23 A P -5.879 0.698 -19.689 O3' -4.885 -4.787 -21.034 24 A P -6.056 -5.477 -20.187 O3' -4.594 -10.345 -19.911 25 U P -5.384 -11.121 -18.726 O3' -4.080 -14.510 -15.337 26 G P -5.237 -14.544 -14.194 O3' -5.469 -14.824 -9.026 27 G P -7.064 -14.656 -8.813 O3' -8.783 -12.017 -4.511 28 G P -10.313 -12.526 -4.663 O3' -14.067 -9.859 -2.777 29 C P -15.431 -10.559 -3.286 O3' -19.653 -8.032 -5.043 30 G P -20.700 -9.159 -5.536 O3' -24.475 -8.526 -10.094 31 C P -25.361 -9.865 -10.274 O3' -26.855 -10.037 -15.008 32 P O3' -27.952 -14.607 -18.050 P -27.873 -11.242 -14.687 33 U P -29.207 -15.099 -17.119 O3' -29.853 -20.234 -17.573 34 G P -31.330 -20.253 -16.913 O3' -30.399 -20.986 -11.822 35 U P -28.954 -20.274 -11.878 O3' -24.723 -21.267 -9.511 36 C P -23.291 -20.712 -10.026 O3' -18.630 -21.946 -10.348 37 g P -18.273 -20.731 -11.386 O3' -14.563 -21.367 -14.983 38 C P -14.247 -20.257 -16.109 O3' -12.700 -19.169 -20.054 39 G P -12.441 -17.597 -20.187 O3' -14.804 -13.974 -23.146 40 U P -13.789 -12.816 -22.617 O3' -16.279 -8.412 -22.270 41 G P -15.044 -7.472 -21.775 O3' -16.004 -3.140 -18.520 42 C P -14.777 -2.349 -17.805 O3' -15.077 1.009 -13.999 43 C P -13.558 1.258 -13.467 O3' -12.037 2.459 -8.890 44 A P -10.503 2.909 -9.212 O3' -7.269 2.483 -5.663 45 G P -5.804 3.078 -5.850 O3' -0.746 1.054 -6.300 46 A P -0.425 2.630 -6.356 O3' 5.014 3.653 -7.542 47 U P 5.059 5.219 -7.203 O3' 9.664 4.365 -10.757 48 c P 11.249 4.460 -11.044 O3' 11.658 4.468 -5.820 49 G P 11.143 5.977 -5.653 O3' 12.547 8.139 -1.883 50 G P 12.232 9.670 -2.245 O3' 14.449 14.454 -0.716 51 G P 13.877 15.685 -1.596 O3' 16.062 19.923 -2.966 52 G P 15.213 20.785 -4.033 O3' 16.983 23.676 -8.849 53 u O3' 15.297 26.300 -14.440 P 15.691 24.491 -9.404 54 P O3' 10.097 27.556 -17.349 P 13.859 26.926 -14.020 55 C P 9.313 28.386 -16.196 O3' 6.127 25.225 -13.739 56 A P 7.341 24.147 -13.610 O3' 5.576 19.579 -13.856 57 A P 6.804 18.866 -13.116 O3' 7.574 13.845 -15.023 58 U P 7.260 12.610 -14.037 O3' 11.216 10.088 -14.681 59 U P 12.043 11.350 -15.207 O3' 14.314 10.846 -20.527 60 C P 15.874 11.076 -20.037 O3' 19.178 13.964 -19.669 61 C P 20.428 13.553 -18.781 O3' 23.481 16.287 -14.959 62 C P 24.270 14.862 -14.907 O3' 26.786 14.300 -10.278 63 C P 27.276 12.829 -9.844 O3' 27.535 10.701 -5.478 64 G P 27.614 9.125 -5.902 O3' 26.436 5.204 -2.617 65 U P 26.872 3.915 -3.508 O3' 24.670 -0.341 -2.446 66 C P 25.699 -1.302 -3.225 O3' 24.357 -5.532 -5.979 67 G P 25.130 -6.088 -7.273 O3' 24.522 -8.513 -11.387 68 C P 25.521 -8.756 -12.621 O3' 26.447 -8.877 -17.204 69 G P 28.084 -8.784 -17.198 O3' 30.932 -7.450 -20.893 70 G P 32.445 -7.433 -20.312 O3' 36.755 -5.026 -22.413 71 A P 38.050 -5.215 -21.436 O3' 42.016 -2.385 -20.395 72 G P 43.017 -3.219 -19.435 O3' 47.110 -0.076 -17.532 73 C P 48.324 -1.037 -17.098 O3' 52.184 -0.037 -13.236 18 syn 57 syn 1 71 - - c 2 70 + + c 3 69 + + c 4 68 + + c 5 67 W W c 6 66 + + c 7 65 - - c 8 14 W H t 9 23 H H t 10 25 W W c 10 45 H S c 11 24 - - c 12 23 - - c 13 22 W W c 14 21 W S c 15 47 W W t 18 55 + + c 22 46 H W t 26 44 W W c 27 43 + + c 28 42 + + c 29 41 + + c 30 40 W W c 31 39 + + c 48 64 + + c 49 63 + + c 50 62 + + c 51 61 + + c 52 60 + + c 53 57 W H t 7 64 ! ! ! 17 54 ! ! ! 33 36 ! ! ! 54 56 ! ! ! 59 60 ! ! ! 71 72 ! ! ! 1 71 7 48 64 5 10 25 4 26 44 6 SG1 8 9 SG2 14 21 SG3 32 38 SG4 45 47 SG5 53 59 SG6 72 73 1 508.287 27.809 2 508.287 50.983 3 508.287 74.157 4 508.287 97.331 5 508.287 120.505 6 508.287 143.679 7 508.287 166.853 8 522.191 166.853 9 536.096 166.853 10 233.328 329.369 11 256.259 326.024 12 279.190 322.679 13 302.122 319.335 14 323.033 329.678 15 346.280 327.712 16 365.156 314.002 17 374.218 292.504 18 370.851 269.419 19 356.026 251.405 20 334.020 243.658 21 311.180 248.414 22 294.094 264.299 23 271.163 267.644 24 248.232 270.989 25 225.300 274.333 26 179.438 281.023 27 156.506 284.367 28 133.575 287.712 29 110.643 291.057 30 87.712 294.401 31 64.781 297.746 32 42.713 289.253 33 19.678 294.592 34 3.598 311.928 35 0.000 335.298 36 10.123 356.666 37 30.485 368.686 38 54.085 367.223 39 72.808 352.781 40 95.739 349.437 41 118.671 346.092 42 141.602 342.747 43 164.533 339.403 44 187.465 336.058 45 550.000 213.201 46 536.096 213.201 47 522.191 213.201 48 508.287 213.201 49 508.287 236.375 50 508.287 259.549 51 508.287 282.723 52 508.287 305.897 53 519.875 326.508 54 517.917 350.072 55 503.084 368.486 56 480.478 375.419 57 457.872 368.486 58 443.039 350.072 59 441.080 326.508 60 452.669 305.897 61 452.669 282.723 62 452.669 259.549 63 452.669 236.375 64 452.669 213.201 65 452.669 166.853 66 452.669 143.679 67 452.669 120.505 68 452.669 97.331 69 452.669 74.157 70 452.669 50.983 71 452.669 27.809 72 452.669 13.904 73 452.669 0.000