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| Title: | | STRUCTURE OF THE HUMAN G-QUADRUPLEX REVEALS A NOVEL TOPOLOGY | |
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| Molecular Description: | 5'-D((BRU)pApGpGpGp(BRU)pTpApGpGpGpT)-3' |
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| Structural Features: | QUADRUPLE HELIX, LOOP |
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| Nucleic Acid Sequence: |
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| Chains | A,B: | | (BRU) (DA) (DG) (DG) (DG) (BRU) (DT) (DA) (DG) (DG) (DG) (DT) |
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| Primary Citation: | Parkinson, G.N., Lee, M.P., Neidle, S.
Crystal structure of parallel quadruplexes from human telomeric DNA.
Nature
, 417,
pp. 876 - 880, 2002.
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| Experimental Information: | X-RAY DIFFRACTION |
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| Space Group: |
P
31
2
1
|
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| Cell Constants: |
| a = 56.607 | b = 56.607 | c = 40.546 | (Ångstroms) |
 = 90.00 |  = 90.00 |  = 120.00 | (degrees) |
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| Refinement: | The structure was refined using the SHELXL-97 program.
The R value is
18.9
for 2572 reflections
in the resolution range 10. to
2.4 Ångstroms
with Fobs > 0. sigma(Fobs).
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