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| Title: | | CRYSTAL STRUCTURE ANALYSIS OF THE DNA QUADRUPLEX D(TGGGGT) S1 | |
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| Molecular Description: | 5'-D(TpGpGpGpGpT)-3' |
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| Structural Features: | QUADRUPLE HELIX, PARALLEL-STRANDED TETRAPLEX |
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| Nucleic Acid Sequence: |
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| Chains | A, B, C, D, E, F, G, H: | |
(DT) (DG) (DG) (DG) (DG) (DT)
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| Primary Citation: | Caceres, C., Wright, G., Gouyette, C., Parkinson, G., Subirana, J.A.
A Thymine tetrad in d(TGGGGT) quadruplexes stabilized with Tl+1/Na+1 ions
Nucleic Acids Res.
, 32,
pp. 1097 - 1102, 2004.
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| Experimental Information: | X-RAY DIFFRACTION |
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| Space Group: |
P
1
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| Cell Constants: |
| a = 28.259 | b = 35.410 | c = 32.057 | (Ångstroms) |
 = 83.73 |  = 61.78 |  = 76.68 | (degrees) |
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| Crystallization Conditions: |
| Method: | | VAPOR DIFFUSION, HANGING DROP |
| Drop: | | MPD, sodium cacodylate, magnesium chloride, spermine tetrahydrochlorhide, thallium acetate, lysine-anthraquinone, H2O |
| Reservoir: | | sodium cacodylate, magnesium chloride, thallium acetate, H2O |
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| Refinement: | The structure was refined using the CNS 1.1 program.
The R value is
17.3
for 4721 reflections
in the resolution range 18.50 to
2.20 Ångstroms
with Fobs > 2.0 sigma(Fobs).
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