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| Title: |  | INFLUENCE OF GROOVE INTERACTIONS ON THE FORMATION OF DNA HOLLIDAY JUNCTIONS |  |
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| Molecular Description: | 5'-D(CpCp(OIP)GpTpApCp(5CM)pGpG)-3' |
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| Structural Features: | DOUBLE HELIX, Holliday junction |
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| Nucleic Acid Sequence: |
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| Chains | A, B: | |
(DC) (DC) (DI) (DG) (DT) (DA) (DC) (5CM) (DG) (DG)
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| Primary Citation: | Hays, F.A., Jones, Z.J., Ho, P.S.
Influence of minor groove substituents on the structure of DNA holliday junctions.
Biochemistry
, 43,
pp. 9813 - 9822, 2004.
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| Experimental Information: | X-RAY DIFFRACTION |
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| Space Group: |
C
1
2
1
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| Cell Constants: |
| a = 64.923 | b = 24.869 | c = 37.095 | (Ångstroms) |
= 90.00 | = 109.22 | = 90.00 | (degrees) |
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| Crystallization Conditions: |
| Method: | | VAPOR DIFFUSION, SITTING DROP |
| Drop: | | Na Cacodylate, .5mM DNA, CaCl2, spermine |
| Reservoir: | | MPD, Na Cacodylate |
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| Refinement: | The structure was refined using the CNS 1.1 program.
The R value is
23.6
for 2852 reflections
in the resolution range 18.2 to
2.20 Ångstroms
with I > 0 sigma(I).
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