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| Title: | | CRYSTAL STRUCTURE OF THE DNA DECAMER D(AGG(BR)CATGCCT): COMPARISON WITH D(AGGCATGCCT) AND IMPLICATIONS FOR COBALT HEXAMMINE BINDING TO DNA | |
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| Molecular Description: | 5'-D(ApGpGp(CBR)pApTpGpCpCpT)-3' |
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| Structural Features: | A DOUBLE HELIX, FLIPPED-OUT BASE, BASE TRIPLET |
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| Nucleic Acid Sequence: |
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| Chain | A: | |
(DA) (DG) (DG) (CBR) (DA) (DT) (DG) (DC) (DC) (DT)
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| Primary Citation: | Nunn, C.M.
Crystal structure of d(AGGBrCATGCCT): implications for cobalt hexammine binding to DNA
J.Biomol.Struct.Dyn.
, 14,
pp. 49 - 56, 1996.
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| Experimental Information: | X-RAY DIFFRACTION |
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| Space Group: |
P
61
2
2
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| Cell Constants: |
| a = 33.200 | b = 33.200 | c = 77.100 | (Ångstroms) |
 = 90.00 |  = 90.00 |  = 120.00 | (degrees) |
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| Crystallization Conditions: |
| Method: | | VAPOR DIFFUSION, SITTING DROP |
| Drop: | | WATER, MPD, Na Cacodylate, NH4OH, [CO(NH3)6]CL3, WATER |
| Reservoir: | | MPD, WATER |
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| Refinement: | The structure was refined using the X-PLOR program.
The R value is
19.6
for 1748 reflections
in the resolution range 8.000 to
2.000 Ångstroms
with Fobs > 2.000 sigma(Fobs).
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