NDB ID: UHJ055


Title:THE STRUCTURE OF AN RNA/DNA HYBRID: A SUBSTRATE OF THE RIBONUCLEASE ACTIVITY OF HIV-1 REVERSE TRANSCRIPTASE
Molecular Description:5'-R(UpUpCpGpGpGpCpGpCpC)-3'/5'-D(GpGpCp
GpCpCpCpGpApA)-3'
Structural Features:RH DOUBLE HELIX
Nucleic Acid Sequence:
ChainA:U U C G G G C G C C
ChainB:(DG) (DG) (DC) (DG) (DC) (DC) (DC) (DG) (DA) (DA)
Primary Citation:Horton, N.C., Finzel, B.C.
The structure of an RNA/DNA hybrid: a substrate of the ribonuclease activity of HIV-1 reverse transcriptase.
J.Mol.Biol. , 264, pp. 521 - 533, 1996.
Experimental Information:X-RAY DIFFRACTION
Space Group: 43   2
Cell Constants:
a = 31.300b = 31.300c = 137.700(Ångstroms)
= 90.00 = 90.00 = 90.00(degrees)
Refinement:The structure was refined using the X-PLOR program. The R value is 14.5 for 2457 reflections in the resolution range 5.000 to 2.300 Ångstroms with Fobs > 2.000 sigma(Fobs).

Biological Assembly 1
Other Views
Asymmetric Unit
Crystal Packing
RNA View
RNAML File
Enlarge Biological Assembly 1



Coordinate + Structure Data

Asymmetric Unit coordinates (pdb format, Unix compressed(.gz))

Asymmetric Unit coordinates (cif format, Unix compressed(.gz))

Biological Assembly coordinates (pdb format)

Structure Factors (cif format)

XML | Complete with coordinates (xml format, GNU compressed(.gz))
XML | Coordinates only (xml format, GNU compressed(.gz))
XML | Header only (xml format, GNU compressed(.gz))

Derivative Data

Nucleic Acid Backbone Torsions

Base Pair Parameters

Base Pair Step Parameters

Hydrogen Bonding Classification

Links

The RCSB Protein Data Bank: 1FIX

PubMed: 8969302




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