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| Title: | | THREE-DIMENSIONAL STRUCTURE OF A HAMMERHEAD RIBOZYME | |
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| Molecular Description: | RNA/DNA HAMMERHEAD RIBOZYME |
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| Structural Features: | HAMMERHEAD, LOOP |
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| Nucleic Acid Sequence: |
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| Chains | A, C, E: | |
G G C G A C C C U G A U G A G G C C G A A A G G C C G A A A C C G U
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| Chains | B, D, F: | |
(DA) (DC) (DG) (DG) (DT) (DC) (DG) (DG) (DT) (DC) (DG) (DC) (DC)
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| Primary Citation: | Pley, H.W., Flaherty, K.M., McKay, D.B.
Three-dimensional structure of a hammerhead ribozyme.
Nature
, 372,
pp. 68 - 74, 1994.
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| Experimental Information: | X-RAY DIFFRACTION |
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| Space Group: |
P
32
2
1
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| Cell Constants: |
| a = 89.740 | b = 89.740 | c = 185.780 | (Ångstroms) |
 = 90.00 |  = 90.00 |  = 120.00 | (degrees) |
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| Crystallization Conditions: |
| Method: | | VAPOR DIFFUSION, HANGING DROP |
| Drop: | | WATER, NH4 SULFATE, MgCl2, SPERMINE, CACODYLATE |
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| Refinement: | The structure was refined using the X-PLOR program.
The R value is
25.7
for 24660 reflections
in the resolution range 8.000 to
2.600 Ångstroms
with Fobs > 2.000 sigma(Fobs).
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