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| Title: | | CRYSTAL STRUCTURE OF BACKBONE MODIFIED PNA HEXAMER | |
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| Molecular Description: | PEPTIDE NUCLEIC ACID 5'-(CP1GPNTP1APNCP1
GPNLYS)-3' |
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| Structural Features: | DOUBLE HELIX, RIGH AND LEFT HANDED HELICES |
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| Nucleic Acid Sequence: |
| | | |
| Chains | A, B, C, D, E, F, G, H: | |
(CP1) (GPN) (TP1) (APN) (CP1) (GPN) K
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| Primary Citation: | Haima, G., Rasmussen, H., Schmidt, G., Jensen, D.K., Kastrup, J.S., Stafshede, P.W., Norden, B., Buchardt, O., Nielsen, P.E.
Peptide Nucleic Acids (PNA) derived from N-(N-methylaminoethyl)glycine. Synthesis, hybridization and structural properties
New J.Chem.
, 23,
pp. 833 - 840, 1999.
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| Experimental Information: | X-RAY DIFFRACTION |
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| Space Group: |
P
1
21
1
|
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| Cell Constants: |
| a = 48.950 | b = 31.140 | c = 50.390 | (Ångstroms) |
 = 90.00 |  = 110.85 |  = 90.00 | (degrees) |
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| Crystallization Conditions: |
| Method: | | VAPOR DIFFUSION, HANGING DROP |
| Drop: | | MgCl2, TRIS, HEXANEDIOL, ETHANOL |
| Reservoir: | | MgCl2, HEXANEDIOL, ETHANOL |
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| Refinement: | The structure was refined using the X-PLOR 3.851 program.
The R value is
21.4
for 4049 reflections
in the resolution range 6.0 to
2.2 Ångstroms
with Fobs > 3.0 sigma(Fobs).
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