 | | | |
| Title: | | CRYSTAL STRUCTURE OF A PEPTIDE NUCLEIC ACID DUPLEX (BT-PNA) CONTAINING A BICYCLIC ANALOGUE OF THYMINE | |
|
| Molecular Description: | PEPTIDE NUCLEIC ACID 5'-D(GPNOPNAPNTPN
APNCPNLYSNH2)-3' |
 |
| Structural Features: | DOUBLE HELIX |
|
| Nucleic Acid Sequence: |
| | | |
| Chains | A,B,C,D: | | (GPN) (OPN) (APN) (TPN) (APN) (CPN) K (NH2) |
|
|
| Primary Citation: | Eldrup, A.B., Nielsen, B.B., Haaima, G., Rasmussen, H., Kastrup, J.S., Christensen, C., Nielsen, P.E.
1,8-Naphthyridin-2(1H)-ones. Novel Bicyclic and Tricyclic Analogues of Thymine in Peptide Nucleic Acids (PNAs)
Eur.J.Org.Chem.
, 9,
pp. 1781 - 1790, 2001.
|
|
| | | |
| Experimental Information: | X-RAY DIFFRACTION |
|
| Space Group: |
P
21
21
2
|
|
| Cell Constants: |
| a = 30.340 | b = 45.000 | c = 49.280 | (Ångstroms) |
 = 90.00 |  = 90.00 |  = 90.00 | (degrees) |
|
|
| Refinement: | The structure was refined using the X-PLOR 3.851 program.
The R value is
20.8
for 4196 reflections
in the resolution range 6.0 to
1.82 Ångstroms
with I > 0. sigma(I).
|
|
|
