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| Title: | | A PREORGANIZED ACTIVE SITE IN THE CRYSTAL STRUCTURE OF THE TETRAHYMENA RIBOZYME | |
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| Molecular Description: | LSU RRNA GROUP I INTRON |
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| Structural Features: | SINGLE STRAND, LOOPS, FLIPPED-OUT BASES, OVERHANGING BASES |
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| Nucleic Acid Sequence: |
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| Chains | A,B: | | G A C C G U C A A A U U G C G G G A A A G G G G U C A A C A G C C G U U C A G U A C C A A G U C U C A G G G G A A A C U U U G A G A U G G C C U U G C A A A G G G U A U G G U A A U A A G C U G A C G G A C A U G G U C C U A A C C A C G C A G C C A A G U C C U A A G U C A A C A G G A G A C U G U U G A U A U G G A U G C A G U U C A C A G A C U A A A U G U C G G U C G G G G A A G A U G U A U U C U U C U C A U A A G A U A U A G U C G G A C C U C U C C C G A A A G G G A G U U G G A G U A C U C G |
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| Primary Citation: | Golden, B.L., Gooding, A.R., Podell, E.R., Cech, T.R.
A preorganized active site in the crystal structure of the Tetrahymena ribozyme.
Science
, 282,
pp. 259 - 264, 1998.
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| Experimental Information: | X-RAY DIFFRACTION |
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| Space Group: |
P
42
21
2
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| Cell Constants: |
| a = 179.0 | b = 179.0 | c = 199.3 | (Ångstroms) |
 = 90.0 |  = 90.0 |  = 90.0 | (degrees) |
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| Refinement: | The structure was refined using the CNS program.
The R value is
36.9
for 11156 reflections
in the resolution range 10.0 to
5.0 Ångstroms
with Fobs > 2.0 sigma(Fobs).
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