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| Title: | | MOLECULAR RECOGNITION BY THE VITAMIN B12 RNA APTAMER | |
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| Molecular Description: | VITAMIN B12 BINDING RNA
COBALAMIN (VITAMIN B12) |
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| Structural Features: | SINGLE STRAND, LOOPS, FLIPPED-OUT BASES, BASE TRIPLET |
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| Nucleic Acid Sequence: |
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| Chains | A, C, E, G: | |
G G A A C C G G U G C G C A U A A C C A C C U C A G U G C G A G C A A
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| Primary Citation: | Sussman, D., Nix, J.C., Wilson, C.
The structural basis for molecular recognition by the vitamin B 12 RNA aptamer.
Nat.Struct.Biol.
, 7,
pp. 53 - 57, 2000.
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| Experimental Information: | X-RAY DIFFRACTION |
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| Space Group: |
C
2
2
21
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| Cell Constants: |
| a = 91.330 | b = 161.880 | c = 100.960 | (Ångstroms) |
 = 90.00 |  = 90.00 |  = 90.00 | (degrees) |
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| Crystallization Conditions: |
| Method: | | VAPOR DIFFUSION, HANGING DROP |
| Drop: | | LiCl, MgCl2, ISOPROPANOL |
| Reservoir: | | ISOPROPANOL |
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| Refinement: | The structure was refined using the CNS program.
The R value is
20.4
for 13252 reflections
in the resolution range 12.0 to
3.0 Ångstroms
with I > 0.0 sigma(I).
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