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| Title: |  | HIV-1(MAL) RNA DIMERIZATION INITIATION SITE |  |
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| Molecular Description: | HIV-1 DIS(Mal)UU RNA |
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| Structural Features: | SINGLE STRAND, FLIPPED-OUT BASES |
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| Nucleic Acid Sequence: |
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| Chains | A, B, C, D: | |
U U U G C U G A G G U G C A C A C A G C A A U
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| Primary Citation: | Ennifar, E., Walter, P., Ehresmann, B., Ehresmann, C., Dumas, P.
Crystal structures of coaxially stacked kissing complexes of the HIV-1 RNA dimerization initiation site.
Nat.Struct.Biol.
, 8,
pp. 1064 - 1068, 2001.
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| Experimental Information: | X-RAY DIFFRACTION |
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| Space Group: |
C
1
2
1
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| Cell Constants: |
| a = 122.070 | b = 27.320 | c = 92.100 | (Ångstroms) |
= 90.00 | = 93.47 | = 90.00 | (degrees) |
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| Crystallization Conditions: |
| Method: | | VAPOR DIFFUSION, HANGING DROP |
| Drop: | | Isopropanol, MgCl2, spermine, cacodylate |
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| Refinement: | The structure was refined using the CNS 0.4 program.
The R value is
22.7
for 4967 reflections
in the resolution range 8.00 to
3.10 Ångstroms
with Fobs > 2.0 sigma(Fobs).
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