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| Title: | | THE LEADZYME RIBOZYME BOUND TO MG(H2O)6(II) AND SR(II) AT 1.8 A RESOLUTION | |
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| Molecular Description: | 5'-R(CpGpGpApCpCpGpApGpCpCpApG)-3' |
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| Structural Features: | DOUBLE HELIX, bulge, flipped-out bases, overhanging bases |
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| Nucleic Acid Sequence: |
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| Chains | A,C,E,G: | | C G G A C C G A G C C A G |
| Chains | B,D,F,H: | | G C U G G G A G U C C |
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| Primary Citation: | Wedekind, J.E., McKay, D.B.
Crystal structure of the leadzyme at 1.8 A resolution: metal ion binding and the implications for catalytic mechanism and allo site ion regulation.
BIOCHEMISTRY
, 42,
pp. 9554 - 9563, 2003.
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| Experimental Information: | X-RAY DIFFRACTION |
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| Space Group: |
P
61
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| Cell Constants: |
| a = 60.600 | b = 60.600 | c = 133.100 | (Ångstroms) |
 = 90.00 |  = 90.00 |  = 120.00 | (degrees) |
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| Refinement: | The structure was refined using the CNS 1.1 program.
The R value is
21.0
for 23406 reflections
in the resolution range 28.10 to
1.81 Ångstroms
with Fobs > 0.0 sigma(Fobs).
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