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| Title: |  | CRYSTAL STRUCTURE OF A BULGED RNA TETRAPLEX: IMPLICATIONS FOR A NOVEL BINDING SITE IN RNA TETRAPLEX |  |
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| Molecular Description: | 5'-D(UpG)-R(pUpGpGpU)-3' |
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| Structural Features: | QUADRUPLE HELIX, bulge |
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| Nucleic Acid Sequence: |
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| Primary Citation: | Pan, B., Xiong, Y., Shi, K., Sundaralingam, M.
Crystal Structure of a Bulged RNA Tetraplex at 1.1 A Resolution: Implications for a Novel Binding Site in RNA Tetraplex
STRUCTURE
, 11,
pp. 1423 - 1430, 2003.
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| Experimental Information: | X-RAY DIFFRACTION |
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| Space Group: |
P
4
21
2
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| Cell Constants: |
| a = 35.014 | b = 35.014 | c = 22.257 | (Ångstroms) |
= 90.00 | = 90.00 | = 90.00 | (degrees) |
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| Crystallization Conditions: |
| Method: | | VAPOR DIFFUSION, HANGING DROP |
| Drop: | | spermine, potassium chloride, MPD, cacodylate |
| Reservoir: | | potassium chloride, MPD |
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| Refinement: | The structure was refined using the REFMAC 5.1.24 program.
The R value is
12.678
for 5382 reflections
in the resolution range 16.55 to
1.10 Ångstroms
with Fobs > 2.0 sigma(Fobs).
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